GB1425636A - 15alpha,16alpha-methylene-delta4-oestren-17beta-ols - Google Patents
15alpha,16alpha-methylene-delta4-oestren-17beta-olsInfo
- Publication number
- GB1425636A GB1425636A GB682173A GB682173A GB1425636A GB 1425636 A GB1425636 A GB 1425636A GB 682173 A GB682173 A GB 682173A GB 682173 A GB682173 A GB 682173A GB 1425636 A GB1425636 A GB 1425636A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methylene
- dimethyl
- propylenedioxy
- prepared
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003431 steroids Chemical class 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 230000003152 gestagenic effect Effects 0.000 abstract 2
- RFCHIGCGVYWPJC-MBBIOIMISA-N (1R,2S,7R,10S,11R)-7-methylpentacyclo[8.8.0.02,7.03,5.011,16]octadec-15-ene Chemical class C1C2C1C[C@]1(C)[C@@H]2[C@@H]2CCC3=CCCC[C@@H]3[C@H]2CC1 RFCHIGCGVYWPJC-MBBIOIMISA-N 0.000 abstract 1
- 229910007565 Zn—Cu Inorganic materials 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001195 anabolic effect Effects 0.000 abstract 1
- 230000001548 androgenic effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003433 contraceptive agent Substances 0.000 abstract 1
- 230000002254 contraceptive effect Effects 0.000 abstract 1
- TVZPLCNGKSPOJA-UHFFFAOYSA-N copper zinc Chemical compound [Cu].[Zn] TVZPLCNGKSPOJA-UHFFFAOYSA-N 0.000 abstract 1
- NZZFYRREKKOMAT-UHFFFAOYSA-N diiodomethane Chemical compound ICI NZZFYRREKKOMAT-UHFFFAOYSA-N 0.000 abstract 1
- 229940011871 estrogen Drugs 0.000 abstract 1
- 239000000262 estrogen Substances 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- SLCVBVWXLSEKPL-UHFFFAOYSA-N neopentyl glycol Chemical compound OCC(C)(C)CO SLCVBVWXLSEKPL-UHFFFAOYSA-N 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000006213 oxygenation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2207421A DE2207421C3 (de) | 1972-02-11 | 1972-02-11 | 15α, 16α -Methylen-4-östren-17β -ole bzw. -acylate, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1425636A true GB1425636A (en) | 1976-02-18 |
Family
ID=5836211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB682173A Expired GB1425636A (en) | 1972-02-11 | 1973-02-12 | 15alpha,16alpha-methylene-delta4-oestren-17beta-ols |
Country Status (29)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007027636A1 (de) | 2007-06-12 | 2008-12-18 | Bayer Schering Pharma Aktiengesellschaft | 17ß-Cyano-18a-homo-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel |
| DE102007027637A1 (de) | 2007-06-12 | 2008-12-18 | Bayer Schering Pharma Aktiengesellschaft | 17ß-Cyano-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT274653B (de) * | 1966-11-10 | 1969-09-25 | Alexander Schoeller & Co Kg | Stapelbarer, quaderförmiger, geschlossener Transportbehälter aus Kunststoff für feinkörnige Schüttgüter und Flüssigkeiten |
-
0
- BE BE795241D patent/BE795241A/xx not_active IP Right Cessation
-
1972
- 1972-02-11 DE DE2207421A patent/DE2207421C3/de not_active Expired
- 1972-12-29 PL PL1972159970A patent/PL81084B1/pl unknown
-
1973
- 1973-01-11 DD DD168198A patent/DD102379A5/xx unknown
- 1973-01-16 DK DK24273AA patent/DK131037B/da not_active IP Right Cessation
- 1973-01-23 FI FI730169A patent/FI52225C/fi active
- 1973-01-24 ES ES410933A patent/ES410933A1/es not_active Expired
- 1973-01-31 CS CS73748A patent/CS193019B2/cs unknown
- 1973-01-31 YU YU243/73A patent/YU35035B/xx unknown
- 1973-02-06 IE IE190/73A patent/IE37266B1/xx unknown
- 1973-02-06 CA CA163,029A patent/CA997753A/en not_active Expired
- 1973-02-07 EG EG49/73A patent/EG10914A/xx active
- 1973-02-08 AT AT112473A patent/AT327413B/de not_active IP Right Cessation
- 1973-02-09 ZA ZA730944A patent/ZA73944B/xx unknown
- 1973-02-09 GR GR1318A patent/GR63160B/el unknown
- 1973-02-09 CH CH535776A patent/CH593995A5/xx not_active IP Right Cessation
- 1973-02-09 IL IL41506A patent/IL41506A/en unknown
- 1973-02-09 CH CH186373A patent/CH590883A5/xx not_active IP Right Cessation
- 1973-02-09 FR FR7304678A patent/FR2181719B1/fr not_active Expired
- 1973-02-09 NO NO528/73A patent/NO140304C/no unknown
- 1973-02-09 PH PH14330*UA patent/PH9370A/en unknown
- 1973-02-09 SU SU1891803A patent/SU513628A3/ru active
- 1973-02-10 HU HUSE1666A patent/HU165253B/hu unknown
- 1973-02-10 KR KR7300246A patent/KR780000156B1/ko not_active Expired
- 1973-02-10 RO RO7373805A patent/RO73527A/ro unknown
- 1973-02-12 NL NLAANVRAGE7301974,A patent/NL177217C/xx not_active IP Right Cessation
- 1973-02-12 GB GB682173A patent/GB1425636A/en not_active Expired
- 1973-02-12 JP JP48017357A patent/JPS5829317B2/ja not_active Expired
- 1973-02-12 SE SE7301935A patent/SE403781B/xx unknown
- 1973-02-12 AU AU52076/73A patent/AU467306B2/en not_active Expired
-
1975
- 1975-12-22 SE SE7514513A patent/SE409329B/xx not_active IP Right Cessation
-
1977
- 1977-12-07 SE SE7713896A patent/SE426834B/sv not_active IP Right Cessation
-
1978
- 1978-08-14 NO NO782754A patent/NO143065C/no unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |