GB1425261A - Nitroimidazolyl-pyrimidines - Google Patents
Nitroimidazolyl-pyrimidinesInfo
- Publication number
- GB1425261A GB1425261A GB794173A GB794173A GB1425261A GB 1425261 A GB1425261 A GB 1425261A GB 794173 A GB794173 A GB 794173A GB 794173 A GB794173 A GB 794173A GB 1425261 A GB1425261 A GB 1425261A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydrogen
- alkyl
- compounds
- phenyl
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UTMABVXKQIDJCX-UHFFFAOYSA-N 2-(1h-imidazol-2-yl)-4-nitropyrimidine Chemical class [O-][N+](=O)C1=CC=NC(C=2NC=CN=2)=N1 UTMABVXKQIDJCX-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- -1 alkane carboxylic acid Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- GQXZMGLLNZTTNN-UHFFFAOYSA-N 2-(5-nitro-1h-imidazol-2-yl)pyrimidine Chemical class N1C([N+](=O)[O-])=CN=C1C1=NC=CC=N1 GQXZMGLLNZTTNN-UHFFFAOYSA-N 0.000 abstract 1
- NVKJOXRVEKMMHS-UHFFFAOYSA-N 5-nitro-1,2,4-triazol-3-one Chemical compound [O-][N+](=O)C1=NC(=O)N=N1 NVKJOXRVEKMMHS-UHFFFAOYSA-N 0.000 abstract 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 235000019270 ammonium chloride Nutrition 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000002081 enamines Chemical class 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000005113 hydroxyalkoxy group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000002911 monocyclic heterocycle group Chemical group 0.000 abstract 1
- 125000005188 oxoalkyl group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722208518 DE2208518A1 (de) | 1972-02-19 | 1972-02-19 | Nitroimidazole |
| DE19722255079 DE2255079A1 (de) | 1972-11-07 | 1972-11-07 | Nitroimidazolylpyrimidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1425261A true GB1425261A (en) | 1976-02-18 |
Family
ID=25762760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB794173A Expired GB1425261A (en) | 1972-02-19 | 1973-02-19 | Nitroimidazolyl-pyrimidines |
Country Status (11)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH612432A5 (enrdf_load_stackoverflow) * | 1975-05-12 | 1979-07-31 | Sandoz Ag | |
| US4256887A (en) * | 1978-04-06 | 1981-03-17 | Merck & Co., Inc. | 1,2,4-Triazoles and a method for their preparation |
| US4323570A (en) * | 1978-11-15 | 1982-04-06 | Beiersdorf Aktiengesellschaft | Substituted aminopyrimidines |
| US4434167A (en) | 1979-11-07 | 1984-02-28 | Beiersdorf Aktiengesellschaft | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia |
| US4769378A (en) * | 1986-03-31 | 1988-09-06 | Eli Lilly And Company | Indenopyrimidine aromatase inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1920635C3 (de) * | 1969-04-19 | 1979-06-28 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 2-(l-MethyI-5-nitro-2-imidazolyl)benzimidazole |
| IT1043840B (it) * | 1971-05-08 | 1980-02-29 | Poli Ind Chimica Spa | Pirimidine 2 5 disostituite e processo per la loro preparazione |
-
0
- BE BE795636D patent/BE795636A/xx unknown
-
1972
- 1972-12-27 DD DD167919A patent/DD105226A5/xx unknown
-
1973
- 1973-02-09 US US331114A patent/US3920655A/en not_active Expired - Lifetime
- 1973-02-16 FR FR7305530A patent/FR2183670B1/fr not_active Expired
- 1973-02-16 CH CH227973A patent/CH577995A5/xx not_active IP Right Cessation
- 1973-02-16 AT AT141973A patent/AT328455B/de not_active IP Right Cessation
- 1973-02-19 NL NL7302292A patent/NL7302292A/xx not_active Application Discontinuation
- 1973-02-19 JP JP48020097A patent/JPS4886881A/ja active Pending
- 1973-02-19 GB GB794173A patent/GB1425261A/en not_active Expired
- 1973-02-19 AU AU52334/73A patent/AU5233473A/en not_active Expired
- 1973-02-19 CA CA164,004A patent/CA974242A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3920655A (en) | 1975-11-18 |
| NL7302292A (enrdf_load_stackoverflow) | 1973-08-21 |
| BE795636A (fr) | 1973-08-20 |
| FR2183670A1 (enrdf_load_stackoverflow) | 1973-12-21 |
| AU5233473A (en) | 1974-08-22 |
| CH577995A5 (enrdf_load_stackoverflow) | 1976-07-30 |
| JPS4886881A (enrdf_load_stackoverflow) | 1973-11-15 |
| CA974242A (en) | 1975-09-09 |
| ATA141973A (de) | 1975-06-15 |
| FR2183670B1 (enrdf_load_stackoverflow) | 1975-10-31 |
| AT328455B (de) | 1976-03-25 |
| DD105226A5 (enrdf_load_stackoverflow) | 1974-04-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 48S | Specification amended (sect. 8/1949) | ||
| PCNP | Patent ceased through non-payment of renewal fee |