GB1423065A - D-6-methyl-2,8-disubstituted ergolines - Google Patents

D-6-methyl-2,8-disubstituted ergolines

Info

Publication number
GB1423065A
GB1423065A GB3289073A GB3289073A GB1423065A GB 1423065 A GB1423065 A GB 1423065A GB 3289073 A GB3289073 A GB 3289073A GB 3289073 A GB3289073 A GB 3289073A GB 1423065 A GB1423065 A GB 1423065A
Authority
GB
United Kingdom
Prior art keywords
methyl
ergoline
formula
reacting
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3289073A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of GB1423065A publication Critical patent/GB1423065A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB3289073A 1972-07-21 1973-07-10 D-6-methyl-2,8-disubstituted ergolines Expired GB1423065A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27390272A 1972-07-21 1972-07-21

Publications (1)

Publication Number Publication Date
GB1423065A true GB1423065A (en) 1976-01-28

Family

ID=23045910

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3289073A Expired GB1423065A (en) 1972-07-21 1973-07-10 D-6-methyl-2,8-disubstituted ergolines

Country Status (24)

Country Link
JP (2) JPS576431B2 (id)
AR (3) AR206772A1 (id)
AT (1) AT331425B (id)
BE (1) BE802531A (id)
BG (3) BG22400A3 (id)
CA (1) CA1006159A (id)
CH (5) CH580625A5 (id)
CS (1) CS208164B2 (id)
DD (1) DD107690A5 (id)
DE (2) DE2335750C3 (id)
DK (1) DK140986B (id)
ES (5) ES417078A1 (id)
FR (1) FR2193606B1 (id)
GB (1) GB1423065A (id)
HU (1) HU167274B (id)
IE (1) IE37936B1 (id)
IL (3) IL42730A (id)
NL (1) NL7309969A (id)
PH (1) PH11229A (id)
RO (2) RO71305A (id)
SE (3) SE393111B (id)
SU (3) SU645581A3 (id)
YU (1) YU36953B (id)
ZA (1) ZA734627B (id)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517971A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 8alpha-substituted ergoline i derivatives
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
AU526764B2 (en) * 1978-09-08 1983-01-27 Farmitalia Carlo Erba S.P.A. Ergoline derivatives
DE3587860D1 (de) * 1984-04-09 1994-07-28 Schering Ag 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
HU196598B (en) * 1986-04-25 1988-12-28 Richter Gedeon Vegyeszet Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
JPH0596382U (ja) * 1992-05-28 1993-12-27 イビデン株式会社 ドアユニット

Also Published As

Publication number Publication date
SU645581A3 (ru) 1979-01-30
CS208164B2 (en) 1981-08-31
IL42730A (en) 1976-06-30
NL7309969A (id) 1974-01-23
IL42730A0 (en) 1973-10-25
SU584780A3 (ru) 1977-12-15
ES442885A1 (es) 1977-04-16
JPS5813541B2 (ja) 1983-03-14
JPS5781487A (en) 1982-05-21
CH580625A5 (id) 1976-10-15
SE393111B (sv) 1977-05-02
DD107690A5 (id) 1974-08-12
DK140986C (id) 1980-07-21
BE802531A (fr) 1974-01-21
SE7611467L (sv) 1976-10-15
BG21410A3 (bg) 1976-05-20
FR2193606B1 (id) 1977-07-15
AR206887A1 (es) 1976-08-31
AT331425B (de) 1976-08-25
CH580626A5 (id) 1976-10-15
RO71305A (ro) 1982-03-24
SU575029A3 (ru) 1977-09-30
ATA643473A (de) 1975-11-15
IE37936L (en) 1974-01-21
ZA734627B (en) 1974-06-26
IL48288A0 (en) 1975-12-31
DE2365974A1 (de) 1977-03-24
YU194573A (en) 1982-06-18
HU167274B (id) 1975-09-27
ES417078A1 (es) 1976-05-01
ES446789A1 (es) 1977-06-01
CH578563A5 (id) 1976-08-13
CH581135A5 (id) 1976-10-29
BG22400A3 (bg) 1977-02-20
AR206772A1 (es) 1976-08-23
FR2193606A1 (id) 1974-02-22
AR210072A1 (es) 1977-06-30
IE37936B1 (en) 1977-11-23
BG21411A3 (id) 1976-05-20
IL48288A (en) 1976-06-30
JPS4985099A (id) 1974-08-15
CH578564A5 (id) 1976-08-13
PH11229A (en) 1977-10-28
ES442887A1 (es) 1977-05-16
SE410459B (sv) 1979-10-15
JPS576431B2 (id) 1982-02-04
ES442886A1 (es) 1977-04-16
AU5792673A (en) 1975-01-16
RO63792A (fr) 1978-12-15
YU36953B (en) 1984-08-31
DE2335750C3 (de) 1978-10-19
DE2335750B2 (de) 1978-02-23
DE2335750A1 (de) 1974-02-14
CA1006159A (en) 1977-03-01
DK140986B (da) 1979-12-17
SE410603B (sv) 1979-10-22
SE7611466L (sv) 1976-10-15

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee