GB1420411A - Pyridine compounds and process for their manufacture - Google Patents

Pyridine compounds and process for their manufacture

Info

Publication number
GB1420411A
GB1420411A GB773773A GB773773A GB1420411A GB 1420411 A GB1420411 A GB 1420411A GB 773773 A GB773773 A GB 773773A GB 773773 A GB773773 A GB 773773A GB 1420411 A GB1420411 A GB 1420411A
Authority
GB
United Kingdom
Prior art keywords
optionally substituted
group
feb
methyl
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB773773A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of GB1420411A publication Critical patent/GB1420411A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/83Thioacids; Thioesters; Thioamides; Thioimides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB773773A 1972-02-17 1973-02-16 Pyridine compounds and process for their manufacture Expired GB1420411A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH189075A CH567474A5 (US20080094685A1-20080424-C00004.png) 1972-02-17 1972-02-17
CH230172A CH570376A5 (US20080094685A1-20080424-C00004.png) 1972-02-17 1972-02-17
CH1354372 1972-09-15
CH1872972 1972-12-22

Publications (1)

Publication Number Publication Date
GB1420411A true GB1420411A (en) 1976-01-07

Family

ID=27428312

Family Applications (1)

Application Number Title Priority Date Filing Date
GB773773A Expired GB1420411A (en) 1972-02-17 1973-02-16 Pyridine compounds and process for their manufacture

Country Status (11)

Country Link
US (1) US3914239A (US20080094685A1-20080424-C00004.png)
JP (1) JPS4892376A (US20080094685A1-20080424-C00004.png)
AT (3) AT327903B (US20080094685A1-20080424-C00004.png)
AU (1) AU5219173A (US20080094685A1-20080424-C00004.png)
BE (1) BE795518A (US20080094685A1-20080424-C00004.png)
CH (2) CH567474A5 (US20080094685A1-20080424-C00004.png)
DE (1) DE2306671A1 (US20080094685A1-20080424-C00004.png)
FR (1) FR2181735B1 (US20080094685A1-20080424-C00004.png)
GB (1) GB1420411A (US20080094685A1-20080424-C00004.png)
NL (1) NL7302228A (US20080094685A1-20080424-C00004.png)
OA (1) OA04290A (US20080094685A1-20080424-C00004.png)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4055649A (en) 1976-02-05 1977-10-25 Sandoz, Inc. 4-Alkyl-2,6-di-(secondary or tertiary alkyl)amino-3-formylpyridines pharmaceutical compositions thereof and their use in the treatment of obesity and diabetes
US4070449A (en) 1972-10-24 1978-01-24 Wilkinson Sword Limited Compounds having a physiological cooling effect and compositions containing them

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5826340B2 (ja) * 1974-05-28 1983-06-02 萬有製薬株式会社 5 − ( ハロブチル ) ピコリンサンアミドノセイホウ
JPS5826341B2 (ja) * 1974-05-28 1983-06-02 萬有製薬株式会社 5 − ( ハロブチル ) ピコリンサンアミドノセイホウ
US4025333A (en) * 1975-01-17 1977-05-24 The Dow Chemical Company Selectively herbicidal 4,6-dibromo-5-hydroxy-2-pyridine carboxamide, salts and esters thereof and methods of preparation and use
US4036965A (en) * 1976-03-04 1977-07-19 Ciba-Geigy Corporation 5-Sulfinyl-2-pyridinecarboxylic acids
US4198416A (en) * 1976-09-30 1980-04-15 Meiji Seika Kaisha, Ltd. 5-Alkoxy-picolinic esters and anti-hypertensive composition containing 5-alkoxy-picolinic esters
JPS5344572A (en) * 1976-09-30 1978-04-21 Meiji Seika Kaisha Ltd 5-alkoxy-picolic acid, its preparation and hypotensives containing the same
US4273779A (en) * 1976-12-23 1981-06-16 Ciba-Geigy Corporation Treating hypertension with substituted-5-amino-2-pyridinecarboxylic acids
DE3165316D1 (en) * 1980-02-21 1984-09-13 Ishihara Sangyo Kaisha 2-substituted-5-trifluoromethylpyridines and a process for producing the same
US4487761A (en) * 1982-04-05 1984-12-11 Merck & Co., Inc. Dopamine β-hydroxylase inhibitors
FR2624857B1 (fr) * 1987-12-16 1991-03-22 Irceba Derives de nicotinoyl-piperazine, procede de preparation et utilisation en therapeutique
KR101409710B1 (ko) * 2006-09-07 2014-06-24 엔쏜 인코포레이티드 전도성 중합체의 전착 및 비전도성 기판의 금속화

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3519717A (en) * 1968-01-17 1970-07-07 Schering Corp Novel method for lowering high blood pressure and compositions therefor
GB1219176A (en) * 1968-04-05 1971-01-13 Scherico Ltd Antihypertensive compositions and their preparation
BE757336A (en) * 1970-10-09 1971-03-16 Zaidan Hotin Biseibutsu Kagaku 5-butyl-and5-pentyl-picolinic acids active - as dopamene-b-hydroxylase inhibitors

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070449A (en) 1972-10-24 1978-01-24 Wilkinson Sword Limited Compounds having a physiological cooling effect and compositions containing them
US4055649A (en) 1976-02-05 1977-10-25 Sandoz, Inc. 4-Alkyl-2,6-di-(secondary or tertiary alkyl)amino-3-formylpyridines pharmaceutical compositions thereof and their use in the treatment of obesity and diabetes

Also Published As

Publication number Publication date
FR2181735A1 (US20080094685A1-20080424-C00004.png) 1973-12-07
OA04290A (fr) 1979-12-31
CH570376A5 (US20080094685A1-20080424-C00004.png) 1975-12-15
ATA723574A (de) 1975-05-15
US3914239A (en) 1975-10-21
CH567474A5 (US20080094685A1-20080424-C00004.png) 1975-10-15
DE2306671A1 (de) 1973-08-23
JPS4892376A (US20080094685A1-20080424-C00004.png) 1973-11-30
AT326656B (de) 1975-12-29
AT327903B (de) 1976-02-25
AT326661B (de) 1975-12-29
AU5219173A (en) 1974-08-15
BE795518A (fr) 1973-08-16
NL7302228A (US20080094685A1-20080424-C00004.png) 1973-08-21
ATA140973A (de) 1975-03-15
ATA723474A (de) 1975-03-15
FR2181735B1 (US20080094685A1-20080424-C00004.png) 1976-05-14

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees