GB1414842A - 2,5-anhydro-d-alloses - Google Patents

2,5-anhydro-d-alloses

Info

Publication number
GB1414842A
GB1414842A GB5099374A GB5099374A GB1414842A GB 1414842 A GB1414842 A GB 1414842A GB 5099374 A GB5099374 A GB 5099374A GB 5099374 A GB5099374 A GB 5099374A GB 1414842 A GB1414842 A GB 1414842A
Authority
GB
United Kingdom
Prior art keywords
yloxy
benzyloxy
compounds
same
methoxytetrahydropyran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5099374A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of GB1414842A publication Critical patent/GB1414842A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals

Abstract

1414842 2,5-anhydro-D-alloses SYNTEX (USA) Inc 6 Feb 1973 [11 Feb 1972] 50993/74 Divided out of 1414841 Heading C2C Compounds II in which OR<SP>3</SP>, is a C 1-12 hydrolysable acyloxy group, t-butoxy, tetrahydropyran-2<SP>1</SP>-yloxy, 4<SP>1</SP>- methoxytetrahydropyran-4<SP>1</SP>-yloxy, benzyloxy or benzyloxy substituted by nitro, halo, C 1-6 akyl or C 1-6 alkoxy, OR<SP>1</SP> and OR<SP>2</SP> are the same and are selected from the same groups as OR<SP>3</SP> or together form an alkylidenedioxy or cycloalkylidenedioxy group having up to 10 C atoms and R is optionally substituted phenyl are prepared by (1) treating a compound I in dichloromethane with p-toluenesulphonic acid in acetone or (2) treating a compound I with an ion exchange resin in hydrogen form in a suitable solvent. Compounds II are novel except when OR<SP>1</SP>, OR<SP>2</SP> and OR<SP>3</SP> are benzyloxy. Compounds I prepared are those in which (a) OR<SP>1</SP>, OR<SP>2</SP> and OR<SP>3</SP> are the same and are benzoyloxy, benzyloxy, acetyloxy, t-butoxy, tetrahydropyran-2<SP>1</SP>- yloxy or 4<SP>1</SP>-methoxytetrahydropyran-4<SP>1</SP>-yloxy or (b) OR<SP>3</SP> is benzoyloxy and OR<SP>1</SP> and OR<SP>2</SP> are isopropylidenedioxy.
GB5099374A 1972-02-11 1973-02-06 2,5-anhydro-d-alloses Expired GB1414842A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22561372A 1972-02-11 1972-02-11

Publications (1)

Publication Number Publication Date
GB1414842A true GB1414842A (en) 1975-11-19

Family

ID=22845555

Family Applications (2)

Application Number Title Priority Date Filing Date
GB5099374A Expired GB1414842A (en) 1972-02-11 1973-02-06 2,5-anhydro-d-alloses
GB585873A Expired GB1414841A (en) 1972-02-11 1973-02-06 2,5-anhydro-dalloses derivatives thereof and c-glycosylnucleosides derived therefrom

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB585873A Expired GB1414841A (en) 1972-02-11 1973-02-06 2,5-anhydro-dalloses derivatives thereof and c-glycosylnucleosides derived therefrom

Country Status (5)

Country Link
JP (1) JPS4891053A (en)
DE (1) DE2305894A1 (en)
ES (1) ES411472A1 (en)
FR (1) FR2181721B1 (en)
GB (2) GB1414842A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2529311A1 (en) * 2003-03-28 2004-10-07 Pharmasset, Inc. Compounds for the treatment of flaviviridae infections

Also Published As

Publication number Publication date
JPS4891053A (en) 1973-11-27
ES411472A1 (en) 1976-03-16
DE2305894A1 (en) 1973-09-06
GB1414841A (en) 1975-11-19
FR2181721B1 (en) 1977-07-01
FR2181721A1 (en) 1973-12-07

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees