GB1412617A - Substituted aryl and aralkyl amides - Google Patents

Substituted aryl and aralkyl amides

Info

Publication number
GB1412617A
GB1412617A GB5254072A GB5254072A GB1412617A GB 1412617 A GB1412617 A GB 1412617A GB 5254072 A GB5254072 A GB 5254072A GB 5254072 A GB5254072 A GB 5254072A GB 1412617 A GB1412617 A GB 1412617A
Authority
GB
United Kingdom
Prior art keywords
hydroxy
hydrogen
zero
radical derived
univalent radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5254072A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of GB1412617A publication Critical patent/GB1412617A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1412617 Substituted aryl and aralkyl amides SCHERICO Ltd 14 Nov 1972 [15 Nov 1971] 52540/72 Heading C2C Novel compounds (I): wherein R is a univalent radical derived from an acyclic aliphatic hydrocarbon having 2 to 19 carbon atoms or a univalent radical derived from a cyclic hydrocarbon and, when R is a univalent radical derived from an acyclic aliphatic hydrocarbon having 2 to 19 carbon atoms (a) n is zero or one and X and Y are hydroxy; or (b) n is two and X and Y are independently hydrogen, fluoro, trifluoromethyl or hydroxy, with the proviso that at least one of X and Y is other than hydrogen and, when X is hydrogen, Y is other than hydroxy; and when R is a univalent radical derived from a cyclic hydrocarbon (a) n is zero and X and Y are hydroxy; or (b) n is one or two and X and Y are independently hydrogen, fluoro, trifluoromethyl or hydroxy, with the proviso that, when n is one, at least one of X and Y is other than hydrogen, or (c) provided R is adamantyl, n is zero, one or two and X and Y are independently hydrogen, fluoro, trifluoromethyl or hydroxy, with the proviso that when n is zero, at least one of X and Y is other than hydrogen, are made by standard methods. Pharmaceutical preparations acting on the CNS and particularly suitable for alleviating Parkinsonism contain (I) as active ingredient.
GB5254072A 1971-11-15 1972-11-14 Substituted aryl and aralkyl amides Expired GB1412617A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19897471A 1971-11-15 1971-11-15

Publications (1)

Publication Number Publication Date
GB1412617A true GB1412617A (en) 1975-11-05

Family

ID=22735679

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5254072A Expired GB1412617A (en) 1971-11-15 1972-11-14 Substituted aryl and aralkyl amides

Country Status (11)

Country Link
JP (1) JPS4857939A (en)
AU (1) AU473705B2 (en)
BE (1) BE791392A (en)
CA (1) CA992074A (en)
DE (1) DE2254566A1 (en)
FR (1) FR2160451B1 (en)
GB (1) GB1412617A (en)
HU (1) HU169134B (en)
IL (1) IL40839A0 (en)
NL (1) NL7215389A (en)
ZA (1) ZA728057B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2168976A (en) * 1984-12-20 1986-07-02 Procter & Gamble Amides and compositions thereof having anti-inflammatory activity
CN101765367A (en) * 2007-07-30 2010-06-30 R·洛塞 Substances for the protection of cells and/or tissues
FR2964866A1 (en) * 2010-09-22 2012-03-23 Oreal Use of new of known at least one ortho-diphenol compound as antidandruff agent to treat dandruff associated with the proliferation of Malassezia yeasts on the scalp
CN107207416A (en) * 2014-08-29 2017-09-26 株式会社爱茉莉太平洋 Novel adamantine alkane derivatives compound

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62277347A (en) * 1986-02-25 1987-12-02 Microbial Chem Res Found Novel performed chemical mediator aabustatin analog compound
EP2314574A1 (en) * 2005-06-17 2011-04-27 Apogee Biothechnology Corporation Sphingosine kinase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3277107A (en) * 1962-03-16 1966-10-04 Gulf Oil Corp Cyclopropanecarboxamide and cyclopropanethiocarboxamide derivatives
US3246975A (en) * 1962-03-16 1966-04-19 Gulf Oil Corp 1-cyclobutylformamides and use as herbicides

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2168976A (en) * 1984-12-20 1986-07-02 Procter & Gamble Amides and compositions thereof having anti-inflammatory activity
CN101765367A (en) * 2007-07-30 2010-06-30 R·洛塞 Substances for the protection of cells and/or tissues
FR2964866A1 (en) * 2010-09-22 2012-03-23 Oreal Use of new of known at least one ortho-diphenol compound as antidandruff agent to treat dandruff associated with the proliferation of Malassezia yeasts on the scalp
CN107207416A (en) * 2014-08-29 2017-09-26 株式会社爱茉莉太平洋 Novel adamantine alkane derivatives compound
TWI676612B (en) * 2014-08-29 2019-11-11 南韓商愛茉莉太平洋股份有限公司 Novel adamantane derivative compound
CN107207416B (en) * 2014-08-29 2020-02-07 株式会社爱茉莉太平洋 Novel adamantane derivative compound
US10696611B2 (en) 2014-08-29 2020-06-30 Amorepacific Corporation Adamantane derivative compound

Also Published As

Publication number Publication date
CA992074A (en) 1976-06-29
DE2254566A1 (en) 1973-05-24
FR2160451B1 (en) 1977-04-15
BE791392A (en) 1973-05-14
FR2160451A1 (en) 1973-06-29
NL7215389A (en) 1973-05-17
AU4889672A (en) 1974-05-16
IL40839A0 (en) 1973-01-30
JPS4857939A (en) 1973-08-14
AU473705B2 (en) 1976-07-01
HU169134B (en) 1976-09-28
ZA728057B (en) 1973-07-25

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee