GB1409871A - Imidazo 4,5-f quinolin-9-ols - Google Patents
Imidazo 4,5-f quinolin-9-olsInfo
- Publication number
- GB1409871A GB1409871A GB970774A GB970774A GB1409871A GB 1409871 A GB1409871 A GB 1409871A GB 970774 A GB970774 A GB 970774A GB 970774 A GB970774 A GB 970774A GB 1409871 A GB1409871 A GB 1409871A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- prepared
- compound
- furyl
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000001037 p-tolyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)C([H])([H])[H] 0.000 abstract 2
- 238000007363 ring formation reaction Methods 0.000 abstract 2
- LXQOQPGNCGEELI-UHFFFAOYSA-N 2,4-dinitroaniline Chemical compound NC1=CC=C([N+]([O-])=O)C=C1[N+]([O-])=O LXQOQPGNCGEELI-UHFFFAOYSA-N 0.000 abstract 1
- VAOCIPZCVAFPGT-UHFFFAOYSA-N 2-(furan-2-yl)-6-nitro-1h-benzimidazole Chemical compound N1C2=CC([N+](=O)[O-])=CC=C2N=C1C1=CC=CO1 VAOCIPZCVAFPGT-UHFFFAOYSA-N 0.000 abstract 1
- 125000004182 2-chlorophenyl group Chemical group [H]C1=C([H])C(Cl)=C(*)C([H])=C1[H] 0.000 abstract 1
- OFTKFKYVSBNYEC-UHFFFAOYSA-N 2-furoyl chloride Chemical compound ClC(=O)C1=CC=CO1 OFTKFKYVSBNYEC-UHFFFAOYSA-N 0.000 abstract 1
- 125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- KAGWXVBPEQBHQH-UHFFFAOYSA-N 3,6-dihydroimidazo[4,5-f]quinolin-9-one Chemical class C1=C2N=CNC2=C2C(O)=CC=NC2=C1 KAGWXVBPEQBHQH-UHFFFAOYSA-N 0.000 abstract 1
- RAUWPNXIALNKQM-UHFFFAOYSA-N 4-nitro-1,2-phenylenediamine Chemical compound NC1=CC=C([N+]([O-])=O)C=C1N RAUWPNXIALNKQM-UHFFFAOYSA-N 0.000 abstract 1
- KVCDOVPONUELDW-UHFFFAOYSA-N 5-amino-2-(furan-2-yl)-N-phenylbenzamide Chemical compound O1C(=CC=C1)C1=C(C(=O)NC2=CC=CC=C2)C=C(C=C1)N KVCDOVPONUELDW-UHFFFAOYSA-N 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- OMLFDNIEBZUOHS-UHFFFAOYSA-N n-(2-amino-4-nitrophenyl)furan-2-carboxamide Chemical compound NC1=CC([N+]([O-])=O)=CC=C1NC(=O)C1=CC=CO1 OMLFDNIEBZUOHS-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical class C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US367499A US3868378A (en) | 1973-06-06 | 1973-06-06 | Imidazo {8 4,5-f{9 {0 quinolin-9-ols |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1409871A true GB1409871A (en) | 1975-10-15 |
Family
ID=23447421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB970774A Expired GB1409871A (en) | 1973-06-06 | 1974-03-04 | Imidazo 4,5-f quinolin-9-ols |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3868378A (enExample) |
| JP (1) | JPS5019776A (enExample) |
| BE (1) | BE816005A (enExample) |
| CH (1) | CH601295A5 (enExample) |
| DE (1) | DE2427411A1 (enExample) |
| DK (1) | DK133105C (enExample) |
| FR (1) | FR2232319B1 (enExample) |
| GB (1) | GB1409871A (enExample) |
| IL (1) | IL44283A (enExample) |
| NL (1) | NL7403667A (enExample) |
| SE (1) | SE391927B (enExample) |
| ZA (1) | ZA741268B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5265325A (en) * | 1975-11-26 | 1977-05-30 | Kogyo Gijutsuin | Ball valve |
| FR2391214A1 (fr) * | 1977-05-20 | 1978-12-15 | Chauvin Blache Sa Labo | Nouveaux derives de l'indazole, leur procede de preparation et leur application en therapeutique |
| US4716168A (en) * | 1985-01-08 | 1987-12-29 | Norwich Eaton Pharmaceuticals, Inc. | Imidazo(4,5-f)quinolines useful as immunomodulating agents |
| AU2003286757B2 (en) * | 2002-11-01 | 2009-06-04 | Merck Sharp & Dohme Corp. | Carbonylamino-benzimidazole derivatives as androgen receptor modulators |
| WO2016083490A1 (en) * | 2014-11-27 | 2016-06-02 | Remynd Nv | Compounds for the treatment of amyloid-associated diseases |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3517005A (en) * | 1967-10-26 | 1970-06-23 | Pfizer & Co C | Certain 2- and 4-substituted quinazolines |
| US3636216A (en) * | 1968-09-26 | 1972-01-18 | Salsbury Lab | Coccidiosis control with quinalinol derivatives |
| US3506667A (en) * | 1969-05-01 | 1970-04-14 | Warner Lambert Pharmaceutical | Furo quinoline carboxylates |
| CA942310A (en) * | 1969-07-09 | 1974-02-19 | Mitsuo Nakashita | Preparation of n-substituted 6,7-methylenedioxy-4-quinolone derivatives |
| GB1356937A (en) * | 1970-08-27 | 1974-06-19 | Wellcome Found | Pyrimido-isoquinolines |
| US3790576A (en) * | 1972-03-20 | 1974-02-05 | Parke Davis & Co | 9 substituted 4,9-dihydro-1,3,4,4-tetraalkyl-1h-pyrazolo(3,4-b)quinolines |
-
1973
- 1973-06-06 US US367499A patent/US3868378A/en not_active Expired - Lifetime
-
1974
- 1974-02-25 IL IL44283A patent/IL44283A/en unknown
- 1974-02-26 ZA ZA00741268A patent/ZA741268B/xx unknown
- 1974-03-04 GB GB970774A patent/GB1409871A/en not_active Expired
- 1974-03-19 NL NL7403667A patent/NL7403667A/xx not_active Application Discontinuation
- 1974-04-26 SE SE7405654A patent/SE391927B/xx unknown
- 1974-06-04 JP JP49062612A patent/JPS5019776A/ja active Pending
- 1974-06-05 FR FR7419425A patent/FR2232319B1/fr not_active Expired
- 1974-06-06 CH CH774174A patent/CH601295A5/xx not_active IP Right Cessation
- 1974-06-06 DE DE19742427411 patent/DE2427411A1/de not_active Withdrawn
- 1974-06-06 BE BE145154A patent/BE816005A/xx unknown
- 1974-06-06 DK DK302174A patent/DK133105C/da active
Also Published As
| Publication number | Publication date |
|---|---|
| NL7403667A (enExample) | 1974-12-10 |
| FR2232319A1 (enExample) | 1975-01-03 |
| CH601295A5 (enExample) | 1978-07-14 |
| US3868378A (en) | 1975-02-25 |
| ZA741268B (en) | 1975-09-24 |
| BE816005A (fr) | 1974-12-06 |
| IL44283A0 (en) | 1974-05-16 |
| DK133105B (da) | 1976-03-22 |
| JPS5019776A (enExample) | 1975-03-01 |
| DE2427411A1 (de) | 1975-03-13 |
| DK133105C (da) | 1976-08-23 |
| SE391927B (sv) | 1977-03-07 |
| FR2232319B1 (enExample) | 1978-03-24 |
| IL44283A (en) | 1976-12-31 |
| AU6910074A (en) | 1975-11-20 |
| DK302174A (enExample) | 1975-02-03 |
| SE7405654L (enExample) | 1974-12-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |