GB1407805A - Preservation of blood and maintenance of its 2,3-diphosphogly cerate content - Google Patents
Preservation of blood and maintenance of its 2,3-diphosphogly cerate contentInfo
- Publication number
- GB1407805A GB1407805A GB5013772A GB5013772A GB1407805A GB 1407805 A GB1407805 A GB 1407805A GB 5013772 A GB5013772 A GB 5013772A GB 5013772 A GB5013772 A GB 5013772A GB 1407805 A GB1407805 A GB 1407805A
- Authority
- GB
- United Kingdom
- Prior art keywords
- blood
- content
- diphosphogly
- cerate
- preservation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008280 blood Substances 0.000 title abstract 3
- 210000004369 blood Anatomy 0.000 title abstract 3
- XOHUEYCVLUUEJJ-UHFFFAOYSA-I 2,3-Diphosphoglycerate Chemical compound [O-]P(=O)([O-])OC(C(=O)[O-])COP([O-])([O-])=O XOHUEYCVLUUEJJ-UHFFFAOYSA-I 0.000 title abstract 2
- 238000012423 maintenance Methods 0.000 title 1
- 238000004321 preservation Methods 0.000 title 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
- RXKJFZQQPQGTFL-UHFFFAOYSA-N dihydroxyacetone Chemical compound OCC(=O)CO RXKJFZQQPQGTFL-UHFFFAOYSA-N 0.000 abstract 2
- 229930024421 Adenine Natural products 0.000 abstract 1
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 abstract 1
- 229930091371 Fructose Natural products 0.000 abstract 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 abstract 1
- 239000005715 Fructose Substances 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 229930010555 Inosine Natural products 0.000 abstract 1
- UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 229960000643 adenine Drugs 0.000 abstract 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 229940127090 anticoagulant agent Drugs 0.000 abstract 1
- 150000001860 citric acid derivatives Chemical class 0.000 abstract 1
- 239000008121 dextrose Substances 0.000 abstract 1
- 229940120503 dihydroxyacetone Drugs 0.000 abstract 1
- 229930182830 galactose Natural products 0.000 abstract 1
- 229960003786 inosine Drugs 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 239000008174 sterile solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
- A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Physiology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
1407805 Additives for preserved blood AMERICAN HOSPITAL SUPPLY CORP 31 Oct 1972 [1 Nov 1971 (2)] 50137/72 Heading A5B The 2, 3-diphosphoglycerate content of the red cells of blood under storage conditions is maintained or increased by addition of at least 1.5 millimoles/litre of dihydroxyacetone. It may be added as a sterile solution alone or together with conventional preservatives and anticoagulant agents e.g. inosine, adenine, pyruric acid and/or pyrurates, citric acid and/or citrates and a sugar e.g. dextrose fructose, mannose or galactose.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19468971A | 1971-11-01 | 1971-11-01 | |
| US00194652A US3847738A (en) | 1971-11-01 | 1971-11-01 | Blood collection and preservation unit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1407805A true GB1407805A (en) | 1975-09-24 |
Family
ID=26890254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5013772A Expired GB1407805A (en) | 1971-11-01 | 1972-10-31 | Preservation of blood and maintenance of its 2,3-diphosphogly cerate content |
Country Status (10)
| Country | Link |
|---|---|
| BE (1) | BE790740A (en) |
| CA (1) | CA1010788A (en) |
| CH (1) | CH568073A5 (en) |
| DE (1) | DE2246565A1 (en) |
| DK (1) | DK135790B (en) |
| FR (1) | FR2158372B1 (en) |
| GB (1) | GB1407805A (en) |
| IT (1) | IT1048937B (en) |
| NO (1) | NO138507C (en) |
| SE (1) | SE404990B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2581289A1 (en) * | 1985-05-06 | 1986-11-07 | Rgl Transfusion Sanguine Centr | SYNTHETIC SOLUTION FOR THE EXTENDED STORAGE OF ERYTHROCYTA CONCENTRATES |
| US4880786A (en) * | 1987-01-14 | 1989-11-14 | Ube Industries, Ltd. | Additive solution for blood preservation and activation |
-
0
- BE BE790740D patent/BE790740A/en unknown
-
1972
- 1972-09-22 DE DE2246565A patent/DE2246565A1/en not_active Withdrawn
- 1972-10-23 DK DK523472AA patent/DK135790B/en unknown
- 1972-10-27 SE SE7213962A patent/SE404990B/en unknown
- 1972-10-30 IT IT31131/72A patent/IT1048937B/en active
- 1972-10-30 CA CA155,156A patent/CA1010788A/en not_active Expired
- 1972-10-31 NO NO3923/72A patent/NO138507C/en unknown
- 1972-10-31 FR FR7238530A patent/FR2158372B1/fr not_active Expired
- 1972-10-31 GB GB5013772A patent/GB1407805A/en not_active Expired
- 1972-10-31 CH CH1589272A patent/CH568073A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BE790740A (en) | 1973-04-30 |
| SE404990B (en) | 1978-11-13 |
| IT1048937B (en) | 1980-12-20 |
| CH568073A5 (en) | 1975-10-31 |
| DE2246565A1 (en) | 1973-05-03 |
| DK135790B (en) | 1977-06-27 |
| FR2158372B1 (en) | 1976-07-02 |
| DK135790C (en) | 1977-11-28 |
| FR2158372A1 (en) | 1973-06-15 |
| NO138507B (en) | 1978-06-12 |
| CA1010788A (en) | 1977-05-24 |
| NO138507C (en) | 1978-09-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |