GB1405694A - Dynamic multistation photometric analyzer for serological testing - Google Patents

Dynamic multistation photometric analyzer for serological testing

Info

Publication number
GB1405694A
GB1405694A GB3010873A GB3010873A GB1405694A GB 1405694 A GB1405694 A GB 1405694A GB 3010873 A GB3010873 A GB 3010873A GB 3010873 A GB3010873 A GB 3010873A GB 1405694 A GB1405694 A GB 1405694A
Authority
GB
United Kingdom
Prior art keywords
cuvettes
samples
cavities
transfer
loading
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3010873A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Atomic Energy Commission (AEC)
Original Assignee
US Atomic Energy Commission (AEC)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Atomic Energy Commission (AEC) filed Critical US Atomic Energy Commission (AEC)
Publication of GB1405694A publication Critical patent/GB1405694A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/07—Centrifugal type cuvettes

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

1405694 Photometry sample holders UNITED STATES ATOMIC ENERGY COMMISSION 25 June 1973 [2 Aug 1972] 30108/73 Heading G2J A photometric analyzer of the multistation, rotary type has a rotor I comprising a circular array of loading cavities 7 within a circular array of sample analysis cuvettes 8, each cavity 7 being in radial alignment with a cuvette 8 and separated therefrom by a sloping barrier 12 to prevent transfer of liquid from 7 to 8 when the rotor 1 is static but permitting centrifugal transfer. Barrier 12 has a passageway 17 to one side at the top to assist mixing. A drain passageway 9 communicates with the radial extremity of each cuvette 8 and a central dynamic loading and distribution chamber 15 is provided which adjoins the radially inner edges of the loading cavities 7 and has a serrated periphery to cause equal distribution. The cavities 7 and cuvettes 8 may be formed in a PTFE disc 5 held between transparent plates 3, 4 in a steel body 2. In use, samples e.g. of blood are loaded via opening 19 in upper plate 4 or by using a transfer disc. The samples are then centrifugrally transferred to the cuvettes 8 to which access is afforded by recesses 13 in plate 4. The particulates of the samples are thus spread in a thin layer over the outer wall of cuvettes 8 and may be mixed with a diluent stream. After another centrifugal separation, the overlaying liquid may be removed by applying vacuum to drainline 9 or aperture 19 may be sealed and gas pressure applied to the central chamber. Optical Details: Agglomeration is measured by observing rate of sedimentation of resuspended particles using usual photometric techniques. Two radially spaced slit sources may be used to measure the time for the sedimenting boundary to pass from one radius to another. Agglomeration, lysis, fluorescence and radio-activity can be observed with appropriate detectors while supernatant liquid properties such as fluorescence, radio-activity and light absorbency can also be observed.
GB3010873A 1972-08-02 1973-06-25 Dynamic multistation photometric analyzer for serological testing Expired GB1405694A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00277192A US3813031A (en) 1972-08-02 1972-08-02 Rotor having sample holding means

Publications (1)

Publication Number Publication Date
GB1405694A true GB1405694A (en) 1975-09-10

Family

ID=23059806

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3010873A Expired GB1405694A (en) 1972-08-02 1973-06-25 Dynamic multistation photometric analyzer for serological testing

Country Status (17)

Country Link
US (1) US3813031A (en)
JP (1) JPS5536938B2 (en)
AT (1) AT324740B (en)
BE (1) BE802973A (en)
BR (1) BR7305743D0 (en)
CA (1) CA971387A (en)
CH (1) CH567722A5 (en)
DE (1) DE2336619C2 (en)
DK (1) DK148608C (en)
ES (1) ES417075A1 (en)
FR (1) FR2195345A5 (en)
GB (1) GB1405694A (en)
IL (1) IL42632A (en)
IT (1) IT995116B (en)
NL (1) NL177251B (en)
NO (1) NO137920C (en)
SE (1) SE392171B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0106536A2 (en) * 1982-09-15 1984-04-25 Ortho Diagnostic Systems Inc. Carousel microparticle separating, washing and reading device and method of use
FR2557815A1 (en) * 1984-01-11 1985-07-12 Fluilogic Systems Oy CENTRIFUGE FOR LIQUID TREATMENT AT ANALYTICAL SCALE
US4640896A (en) * 1982-11-04 1987-02-03 Unisearch Limited Whole blood clotting timer

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226531A (en) * 1977-08-29 1980-10-07 Instrumentation Laboratory Inc. Disposable multi-cuvette rotor
US4314970A (en) * 1980-08-27 1982-02-09 Instrumentation Laboratory Inc. Analysis system
US4373812A (en) * 1981-03-25 1983-02-15 Instrumentation Laboratory Inc. Cuvette assembly
FR2503866A1 (en) * 1981-04-14 1982-10-15 Guigan Jean DEVICE FOR DELIVERING A DETERMINED DOSE OF A LIQUID SAMPLE IN A CELL AND ASSOCIATED METHOD
FR2511153B1 (en) * 1981-08-05 1986-01-10 Materiel Biomedical MULTIPLE CONTAINER REACTION HOLDER FOR TESTING LIQUID DOSES
DE3315868C2 (en) * 1983-04-30 1985-09-26 Kuiper Medische Instrumenten, Zwolle Device for cleaning disk-shaped analysis cuvettes
US4580896A (en) * 1983-11-07 1986-04-08 Allied Corporation Multicuvette centrifugal analyzer rotor with annular recessed optical window channel
US4902479A (en) * 1983-11-07 1990-02-20 Fisher Scientific Company Centrifugal analyzer rotor
US4580897A (en) * 1984-05-31 1986-04-08 Allied Corporation Centrifugal analyzer rotors
US4580898A (en) * 1984-05-31 1986-04-08 Allied Corporation Analytical system
US5071625A (en) * 1985-02-27 1991-12-10 Fisher Scientific Company Cuvette handling
US4680164A (en) * 1985-07-18 1987-07-14 Fisher Scientific Company Centrifugal analyzer
US4798577A (en) * 1986-05-12 1989-01-17 Miles Inc. Separator device and method
US4828716A (en) * 1987-04-03 1989-05-09 Andronic Devices, Ltd. Apparatus and method for separating phases of blood
US4900446A (en) * 1987-06-23 1990-02-13 Large Scale Biology Centrifugal fast chromatograph
US4900435A (en) * 1988-06-09 1990-02-13 Large Scale Biolocy Centrifugal fast chromatograph
US5271852A (en) * 1992-05-01 1993-12-21 E. I. Du Pont De Nemours And Company Centrifugal methods using a phase-separation tube
US5282981A (en) * 1992-05-01 1994-02-01 E. I. Du Pont De Nemours And Company Flow restrictor-separation device
US5923431A (en) * 1998-04-14 1999-07-13 Uop Llc Spectroscopic helical separator and fluid sample interface
CN101097182B (en) * 2006-06-29 2011-06-15 中国石油化工股份有限公司 Dynamic rotating sample pool and infrared spectrum analysis general purpose accessory
US8293101B2 (en) * 2009-03-13 2012-10-23 Terrasep, Llc Methods and apparatus for centrifugal liquid chromatography

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3547547A (en) * 1969-03-13 1970-12-15 Atomic Energy Commission Analytical photometer with means for measuring,holding and transferring discrete liquid volumes and method of use thereof
US3586484A (en) * 1969-05-23 1971-06-22 Atomic Energy Commission Multistation analytical photometer and method of use

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0106536A2 (en) * 1982-09-15 1984-04-25 Ortho Diagnostic Systems Inc. Carousel microparticle separating, washing and reading device and method of use
EP0106536A3 (en) * 1982-09-15 1986-02-05 Ortho Diagnostic Systems Inc. Carousel microparticle separating, washing and reading device and method of use
US4640896A (en) * 1982-11-04 1987-02-03 Unisearch Limited Whole blood clotting timer
FR2557815A1 (en) * 1984-01-11 1985-07-12 Fluilogic Systems Oy CENTRIFUGE FOR LIQUID TREATMENT AT ANALYTICAL SCALE
US4689203A (en) * 1984-01-11 1987-08-25 Fluilogic Systems Oy Centrifuge

Also Published As

Publication number Publication date
NL7310327A (en) 1974-02-05
DE2336619C2 (en) 1986-10-16
IL42632A (en) 1975-12-31
DK148608B (en) 1985-08-12
DE2336619A1 (en) 1974-02-21
SE392171B (en) 1977-03-14
AU5802173A (en) 1975-01-16
BE802973A (en) 1973-11-16
FR2195345A5 (en) 1974-03-01
BR7305743D0 (en) 1974-07-11
JPS5536938B2 (en) 1980-09-25
NO137920B (en) 1978-02-06
DK148608C (en) 1986-01-27
CA971387A (en) 1975-07-22
CH567722A5 (en) 1975-10-15
US3813031A (en) 1974-05-28
NL177251B (en) 1985-03-18
IL42632A0 (en) 1973-10-25
IT995116B (en) 1975-11-10
JPS4946784A (en) 1974-05-04
NO137920C (en) 1978-05-24
ES417075A1 (en) 1976-03-01
AT324740B (en) 1975-09-10

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
435 Patent endorsed 'licences of right' on the date specified (sect. 35/1949)
PCNP Patent ceased through non-payment of renewal fee