GB1405694A - Dynamic multistation photometric analyzer for serological testing - Google Patents
Dynamic multistation photometric analyzer for serological testingInfo
- Publication number
- GB1405694A GB1405694A GB3010873A GB3010873A GB1405694A GB 1405694 A GB1405694 A GB 1405694A GB 3010873 A GB3010873 A GB 3010873A GB 3010873 A GB3010873 A GB 3010873A GB 1405694 A GB1405694 A GB 1405694A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cuvettes
- samples
- cavities
- transfer
- loading
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/07—Centrifugal type cuvettes
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Optical Measuring Cells (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
1405694 Photometry sample holders UNITED STATES ATOMIC ENERGY COMMISSION 25 June 1973 [2 Aug 1972] 30108/73 Heading G2J A photometric analyzer of the multistation, rotary type has a rotor I comprising a circular array of loading cavities 7 within a circular array of sample analysis cuvettes 8, each cavity 7 being in radial alignment with a cuvette 8 and separated therefrom by a sloping barrier 12 to prevent transfer of liquid from 7 to 8 when the rotor 1 is static but permitting centrifugal transfer. Barrier 12 has a passageway 17 to one side at the top to assist mixing. A drain passageway 9 communicates with the radial extremity of each cuvette 8 and a central dynamic loading and distribution chamber 15 is provided which adjoins the radially inner edges of the loading cavities 7 and has a serrated periphery to cause equal distribution. The cavities 7 and cuvettes 8 may be formed in a PTFE disc 5 held between transparent plates 3, 4 in a steel body 2. In use, samples e.g. of blood are loaded via opening 19 in upper plate 4 or by using a transfer disc. The samples are then centrifugrally transferred to the cuvettes 8 to which access is afforded by recesses 13 in plate 4. The particulates of the samples are thus spread in a thin layer over the outer wall of cuvettes 8 and may be mixed with a diluent stream. After another centrifugal separation, the overlaying liquid may be removed by applying vacuum to drainline 9 or aperture 19 may be sealed and gas pressure applied to the central chamber. Optical Details: Agglomeration is measured by observing rate of sedimentation of resuspended particles using usual photometric techniques. Two radially spaced slit sources may be used to measure the time for the sedimenting boundary to pass from one radius to another. Agglomeration, lysis, fluorescence and radio-activity can be observed with appropriate detectors while supernatant liquid properties such as fluorescence, radio-activity and light absorbency can also be observed.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00277192A US3813031A (en) | 1972-08-02 | 1972-08-02 | Rotor having sample holding means |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1405694A true GB1405694A (en) | 1975-09-10 |
Family
ID=23059806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3010873A Expired GB1405694A (en) | 1972-08-02 | 1973-06-25 | Dynamic multistation photometric analyzer for serological testing |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3813031A (en) |
| JP (1) | JPS5536938B2 (en) |
| AT (1) | AT324740B (en) |
| BE (1) | BE802973A (en) |
| BR (1) | BR7305743D0 (en) |
| CA (1) | CA971387A (en) |
| CH (1) | CH567722A5 (en) |
| DE (1) | DE2336619C2 (en) |
| DK (1) | DK148608C (en) |
| ES (1) | ES417075A1 (en) |
| FR (1) | FR2195345A5 (en) |
| GB (1) | GB1405694A (en) |
| IL (1) | IL42632A (en) |
| IT (1) | IT995116B (en) |
| NL (1) | NL177251B (en) |
| NO (1) | NO137920C (en) |
| SE (1) | SE392171B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0106536A2 (en) * | 1982-09-15 | 1984-04-25 | Ortho Diagnostic Systems Inc. | Carousel microparticle separating, washing and reading device and method of use |
| FR2557815A1 (en) * | 1984-01-11 | 1985-07-12 | Fluilogic Systems Oy | CENTRIFUGE FOR LIQUID TREATMENT AT ANALYTICAL SCALE |
| US4640896A (en) * | 1982-11-04 | 1987-02-03 | Unisearch Limited | Whole blood clotting timer |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4226531A (en) * | 1977-08-29 | 1980-10-07 | Instrumentation Laboratory Inc. | Disposable multi-cuvette rotor |
| US4314970A (en) * | 1980-08-27 | 1982-02-09 | Instrumentation Laboratory Inc. | Analysis system |
| US4373812A (en) * | 1981-03-25 | 1983-02-15 | Instrumentation Laboratory Inc. | Cuvette assembly |
| FR2503866A1 (en) * | 1981-04-14 | 1982-10-15 | Guigan Jean | DEVICE FOR DELIVERING A DETERMINED DOSE OF A LIQUID SAMPLE IN A CELL AND ASSOCIATED METHOD |
| FR2511153B1 (en) * | 1981-08-05 | 1986-01-10 | Materiel Biomedical | MULTIPLE CONTAINER REACTION HOLDER FOR TESTING LIQUID DOSES |
| DE3315868C2 (en) * | 1983-04-30 | 1985-09-26 | Kuiper Medische Instrumenten, Zwolle | Device for cleaning disk-shaped analysis cuvettes |
| US4580896A (en) * | 1983-11-07 | 1986-04-08 | Allied Corporation | Multicuvette centrifugal analyzer rotor with annular recessed optical window channel |
| US4902479A (en) * | 1983-11-07 | 1990-02-20 | Fisher Scientific Company | Centrifugal analyzer rotor |
| US4580897A (en) * | 1984-05-31 | 1986-04-08 | Allied Corporation | Centrifugal analyzer rotors |
| US4580898A (en) * | 1984-05-31 | 1986-04-08 | Allied Corporation | Analytical system |
| US5071625A (en) * | 1985-02-27 | 1991-12-10 | Fisher Scientific Company | Cuvette handling |
| US4680164A (en) * | 1985-07-18 | 1987-07-14 | Fisher Scientific Company | Centrifugal analyzer |
| US4798577A (en) * | 1986-05-12 | 1989-01-17 | Miles Inc. | Separator device and method |
| US4828716A (en) * | 1987-04-03 | 1989-05-09 | Andronic Devices, Ltd. | Apparatus and method for separating phases of blood |
| US4900446A (en) * | 1987-06-23 | 1990-02-13 | Large Scale Biology | Centrifugal fast chromatograph |
| US4900435A (en) * | 1988-06-09 | 1990-02-13 | Large Scale Biolocy | Centrifugal fast chromatograph |
| US5271852A (en) * | 1992-05-01 | 1993-12-21 | E. I. Du Pont De Nemours And Company | Centrifugal methods using a phase-separation tube |
| US5282981A (en) * | 1992-05-01 | 1994-02-01 | E. I. Du Pont De Nemours And Company | Flow restrictor-separation device |
| US5923431A (en) * | 1998-04-14 | 1999-07-13 | Uop Llc | Spectroscopic helical separator and fluid sample interface |
| CN101097182B (en) * | 2006-06-29 | 2011-06-15 | 中国石油化工股份有限公司 | Dynamic rotating sample pool and infrared spectrum analysis general purpose accessory |
| US8277650B2 (en) * | 2009-03-13 | 2012-10-02 | Terrasep, Llc | Methods and apparatus for centrifugal liquid chromatography |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3547547A (en) * | 1969-03-13 | 1970-12-15 | Atomic Energy Commission | Analytical photometer with means for measuring,holding and transferring discrete liquid volumes and method of use thereof |
| US3586484A (en) * | 1969-05-23 | 1971-06-22 | Atomic Energy Commission | Multistation analytical photometer and method of use |
-
1972
- 1972-08-02 US US00277192A patent/US3813031A/en not_active Expired - Lifetime
-
1973
- 1973-06-25 CA CA174,850A patent/CA971387A/en not_active Expired
- 1973-06-25 GB GB3010873A patent/GB1405694A/en not_active Expired
- 1973-06-29 IL IL42632A patent/IL42632A/en unknown
- 1973-07-18 DE DE2336619A patent/DE2336619C2/en not_active Expired
- 1973-07-20 ES ES417075A patent/ES417075A1/en not_active Expired
- 1973-07-21 JP JP8261673A patent/JPS5536938B2/ja not_active Expired
- 1973-07-24 SE SE7310265A patent/SE392171B/en unknown
- 1973-07-25 CH CH1088273A patent/CH567722A5/xx not_active IP Right Cessation
- 1973-07-25 NL NLAANVRAGE7310327,A patent/NL177251B/en not_active IP Right Cessation
- 1973-07-27 BR BR5743/73A patent/BR7305743D0/en unknown
- 1973-07-30 BE BE134020A patent/BE802973A/en not_active IP Right Cessation
- 1973-08-01 DK DK422173A patent/DK148608C/en not_active IP Right Cessation
- 1973-08-01 IT IT27409/73A patent/IT995116B/en active
- 1973-08-02 FR FR7328380A patent/FR2195345A5/fr not_active Expired
- 1973-08-02 NO NO3096/73A patent/NO137920C/en unknown
- 1973-08-02 AT AT678073A patent/AT324740B/en not_active IP Right Cessation
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0106536A2 (en) * | 1982-09-15 | 1984-04-25 | Ortho Diagnostic Systems Inc. | Carousel microparticle separating, washing and reading device and method of use |
| EP0106536A3 (en) * | 1982-09-15 | 1986-02-05 | Ortho Diagnostic Systems Inc. | Carousel microparticle separating, washing and reading device and method of use |
| US4640896A (en) * | 1982-11-04 | 1987-02-03 | Unisearch Limited | Whole blood clotting timer |
| FR2557815A1 (en) * | 1984-01-11 | 1985-07-12 | Fluilogic Systems Oy | CENTRIFUGE FOR LIQUID TREATMENT AT ANALYTICAL SCALE |
| US4689203A (en) * | 1984-01-11 | 1987-08-25 | Fluilogic Systems Oy | Centrifuge |
Also Published As
| Publication number | Publication date |
|---|---|
| BE802973A (en) | 1973-11-16 |
| JPS5536938B2 (en) | 1980-09-25 |
| NL177251B (en) | 1985-03-18 |
| SE392171B (en) | 1977-03-14 |
| FR2195345A5 (en) | 1974-03-01 |
| AT324740B (en) | 1975-09-10 |
| DE2336619A1 (en) | 1974-02-21 |
| DE2336619C2 (en) | 1986-10-16 |
| DK148608C (en) | 1986-01-27 |
| NO137920C (en) | 1978-05-24 |
| IL42632A (en) | 1975-12-31 |
| NL7310327A (en) | 1974-02-05 |
| US3813031A (en) | 1974-05-28 |
| CA971387A (en) | 1975-07-22 |
| CH567722A5 (en) | 1975-10-15 |
| JPS4946784A (en) | 1974-05-04 |
| NO137920B (en) | 1978-02-06 |
| DK148608B (en) | 1985-08-12 |
| IT995116B (en) | 1975-11-10 |
| BR7305743D0 (en) | 1974-07-11 |
| AU5802173A (en) | 1975-01-16 |
| ES417075A1 (en) | 1976-03-01 |
| IL42632A0 (en) | 1973-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 435 | Patent endorsed 'licences of right' on the date specified (sect. 35/1949) | ||
| PCNP | Patent ceased through non-payment of renewal fee |