GB1402349A - Purification process for gn-rh - Google Patents
Purification process for gn-rhInfo
- Publication number
- GB1402349A GB1402349A GB2889873A GB2889873A GB1402349A GB 1402349 A GB1402349 A GB 1402349A GB 2889873 A GB2889873 A GB 2889873A GB 2889873 A GB2889873 A GB 2889873A GB 1402349 A GB1402349 A GB 1402349A
- Authority
- GB
- United Kingdom
- Prior art keywords
- gly
- june
- affinity
- passing
- molecular weights
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000746 purification Methods 0.000 title abstract 2
- XLXSAKCOAKORKW-AQJXLSMYSA-N gonadorelin Chemical compound C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 XLXSAKCOAKORKW-AQJXLSMYSA-N 0.000 abstract 4
- 239000000579 Gonadotropin-Releasing Hormone Substances 0.000 abstract 3
- 101000857870 Squalus acanthias Gonadoliberin Proteins 0.000 abstract 3
- 229940035638 gonadotropin-releasing hormone Drugs 0.000 abstract 3
- 229920005654 Sephadex Polymers 0.000 abstract 2
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 229910000040 hydrogen fluoride Inorganic materials 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00264657A US3816386A (en) | 1972-06-20 | 1972-06-20 | Purification process for gn-rh |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1402349A true GB1402349A (en) | 1975-08-06 |
Family
ID=23007048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2889873A Expired GB1402349A (en) | 1972-06-20 | 1973-06-18 | Purification process for gn-rh |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3816386A (https=) |
| JP (1) | JPS4949962A (https=) |
| AU (1) | AU472111B2 (https=) |
| CA (1) | CA1006509A (https=) |
| FR (1) | FR2189418B1 (https=) |
| GB (1) | GB1402349A (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4305225A1 (de) * | 1993-02-19 | 1994-08-25 | Asta Medica Ag | Neues Herstellverfahren für Cetrorelix Lyophilisat |
| US6828415B2 (en) * | 1993-02-19 | 2004-12-07 | Zentaris Gmbh | Oligopeptide lyophilisate, their preparation and use |
| WO2001002428A1 (en) * | 1999-06-30 | 2001-01-11 | Takeda Chemical Industries, Ltd. | Process for the preparation of lh-rh derivatives |
| US20030144203A1 (en) * | 2001-12-19 | 2003-07-31 | Voyager Pharmaceutical Corporation | Methods for slowing senescence and treating and preventing diseases associated with senescence |
-
1972
- 1972-06-20 US US00264657A patent/US3816386A/en not_active Expired - Lifetime
-
1973
- 1973-05-28 CA CA172,453A patent/CA1006509A/en not_active Expired
- 1973-06-04 AU AU56505/73A patent/AU472111B2/en not_active Expired
- 1973-06-15 JP JP48066975A patent/JPS4949962A/ja active Pending
- 1973-06-18 GB GB2889873A patent/GB1402349A/en not_active Expired
- 1973-06-20 FR FR7322530A patent/FR2189418B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA1006509A (en) | 1977-03-08 |
| AU472111B2 (en) | 1976-05-13 |
| JPS4949962A (https=) | 1974-05-15 |
| US3816386A (en) | 1974-06-11 |
| FR2189418B1 (https=) | 1978-05-26 |
| DE2331095B2 (de) | 1975-08-28 |
| FR2189418A1 (https=) | 1974-01-25 |
| DE2331095A1 (de) | 1974-01-17 |
| AU5650573A (en) | 1974-12-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |