GB1399109A - Basically substituted alkyltheophyline derivatives - Google Patents
Basically substituted alkyltheophyline derivativesInfo
- Publication number
- GB1399109A GB1399109A GB4136472A GB4136472A GB1399109A GB 1399109 A GB1399109 A GB 1399109A GB 4136472 A GB4136472 A GB 4136472A GB 4136472 A GB4136472 A GB 4136472A GB 1399109 A GB1399109 A GB 1399109A
- Authority
- GB
- United Kingdom
- Prior art keywords
- theophylline
- group
- atom
- formula
- denotes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 10
- 229960000278 theophylline Drugs 0.000 abstract 6
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N Theophylline Natural products O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 5
- -1 3 - benzylaminopropyl Chemical group 0.000 abstract 3
- 125000003277 amino group Chemical group 0.000 abstract 3
- 229910052799 carbon Inorganic materials 0.000 abstract 3
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- WGQKYBSKWIADBV-UHFFFAOYSA-N benzylamine Chemical compound NCC1=CC=CC=C1 WGQKYBSKWIADBV-UHFFFAOYSA-N 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000000468 ketone group Chemical group 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000007858 starting material Substances 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- RVMJTHOVOXFBQR-UHFFFAOYSA-N 1,3-dimethyl-8-morpholin-4-yl-7h-purine-2,6-dione Chemical compound N1C=2C(=O)N(C)C(=O)N(C)C=2N=C1N1CCOCC1 RVMJTHOVOXFBQR-UHFFFAOYSA-N 0.000 abstract 1
- FKCAOMADEYRKQQ-UHFFFAOYSA-N 2-chloro-1-(4-hydroxy-3,5-dimethylphenyl)ethanone Chemical compound CC1=CC(C(=O)CCl)=CC(C)=C1O FKCAOMADEYRKQQ-UHFFFAOYSA-N 0.000 abstract 1
- BKFMWOOHKYHNPB-UHFFFAOYSA-N 2-chloro-1-(4-hydroxy-3-methylphenyl)ethanone Chemical compound CC1=CC(C(=O)CCl)=CC=C1O BKFMWOOHKYHNPB-UHFFFAOYSA-N 0.000 abstract 1
- OVKWXBYMGXFCRZ-UHFFFAOYSA-N 7-[3-(benzylamino)propyl]-1,3-dimethylpurine-2,6-dione Chemical compound C1=2C(=O)N(C)C(=O)N(C)C=2N=CN1CCCNCC1=CC=CC=C1 OVKWXBYMGXFCRZ-UHFFFAOYSA-N 0.000 abstract 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- MFESCIUQSIBMSM-UHFFFAOYSA-N I-BCP Chemical compound ClCCCBr MFESCIUQSIBMSM-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT774571A AT311995B (de) | 1971-09-06 | 1971-09-06 | Verfahren zur Herstellung von neuen basisch substituierten Alkyltheophyllinen |
| AT931271A AT313916B (de) | 1971-10-28 | 1971-10-28 | Verfahren zur Herstellung von neuen basisch substituierten Theophyllinen und deren Säureadditionssalzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1399109A true GB1399109A (en) | 1975-06-25 |
Family
ID=25604090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4136472A Expired GB1399109A (en) | 1971-09-06 | 1972-09-06 | Basically substituted alkyltheophyline derivatives |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE788427A (enrdf_load_stackoverflow) |
| CA (1) | CA988086A (enrdf_load_stackoverflow) |
| CH (1) | CH580629A5 (enrdf_load_stackoverflow) |
| DD (1) | DD102385A5 (enrdf_load_stackoverflow) |
| ES (1) | ES406417A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2154457B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1399109A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0011399A1 (en) * | 1978-11-11 | 1980-05-28 | FISONS plc | N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT308139B (de) * | 1970-07-27 | 1973-06-25 | Degussa | Verfahren zur Herstellung von neuen basisch substituierten Alkyltheophyllinen, ihren Isomeren und Säureadditionssalzen |
-
0
- BE BE788427D patent/BE788427A/xx unknown
-
1972
- 1972-09-04 DD DD165427A patent/DD102385A5/xx unknown
- 1972-09-04 FR FR7231262A patent/FR2154457B1/fr not_active Expired
- 1972-09-05 ES ES406417A patent/ES406417A1/es not_active Expired
- 1972-09-06 GB GB4136472A patent/GB1399109A/en not_active Expired
- 1972-09-06 CH CH1310672A patent/CH580629A5/xx not_active IP Right Cessation
- 1972-09-06 CA CA151,076A patent/CA988086A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES406417A1 (es) | 1975-07-01 |
| FR2154457A1 (enrdf_load_stackoverflow) | 1973-05-11 |
| FR2154457B1 (enrdf_load_stackoverflow) | 1975-06-20 |
| CH580629A5 (enrdf_load_stackoverflow) | 1976-10-15 |
| CA988086A (en) | 1976-04-27 |
| DD102385A5 (enrdf_load_stackoverflow) | 1973-12-12 |
| BE788427A (fr) | 1973-03-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1461209A (en) | Thienyl and thietyl compounds | |
| ES357247A1 (es) | Procedimiento para la preparacion de un nuevo derivado de tetrahidroacepina. | |
| FR2435479A1 (fr) | Procede de preparation de composes d'acide 3-cephem-4-carboxylique 3, 7-disubstitue et de leurs sels pharmaceutiquement acceptables, nouveaux produits ainsi obtenus et leur utilisation pour leurs activites antimicrobiennes | |
| IL71617A (en) | 3-(amino-1-carboxylalkyl)amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-acetic acid derivatives,method for producing them and pharmaceutical compositions containing them | |
| GB1488692A (en) | Pyrazolo(3,4,6)quinolines | |
| GB1355147A (en) | Oxoprostanoic acid derivatives | |
| IL33846A (en) | Derivatives of 1-thiachromone and 4-thionchromone,their preparation and pharmaceutical compositions containing them | |
| ES474232A1 (es) | Un metodo para producir 2,6-diaminonebularinas | |
| US2878158A (en) | Carbamic acid ester of phenyl isopropyl carbinol | |
| GB1399109A (en) | Basically substituted alkyltheophyline derivatives | |
| GB1317034A (en) | 1-2-hydroxy-3-phenoxy- or -phenylthiopropyl-piperazine derivatives | |
| ES8401926A1 (es) | Un procedimiento para la preparacion de un compuesto de hidroxibencilaminobenceno, dotado de propiedades antiinflamatorias. | |
| GB1431414A (en) | Prostanoic acid derivatives | |
| DE3483881D1 (de) | 1,3-dioxan-4-ylalkensaeure. | |
| GB1490486A (en) | 4-imino-1,3-diazobicyclo-(3.1.0)hexan-2-one | |
| GB1373900A (en) | Corticoid ester and method of preparing it | |
| MY102090A (en) | Compounds with antiinflammatory activity, process for preparation thereof and pharmaceutical compositions therefrom | |
| US3763169A (en) | Isonipecotic acid compounds | |
| GB1369173A (en) | 5-cinnamoyl-pyrrole-2-acetic acids and esters and pharmaceutical compositions containing them | |
| PL244610A1 (en) | Process for preparing novel derivatives of benzazepine | |
| GB1425729A (en) | 1,4-dihydropyridine compounds | |
| GB1322069A (en) | Aminoalkanoylaminocyclohexane derivatives | |
| GB1205687A (en) | Aminoalkanol esters and their pharmaceutically acceptable acid-addition salts, and production thereof | |
| GB1357711A (en) | Substituted thiazines a process for their p'eparation and phar maceutical compositions comprising them | |
| ES458932A1 (es) | Procedimiento para la obtencion de derivados del 2-oxa-7,9- diaza-bicilo (4,2,2) decano. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |