GB1392658A - Preparation of beta-lactamic antibiotics - Google Patents
Preparation of beta-lactamic antibioticsInfo
- Publication number
- GB1392658A GB1392658A GB2275072A GB2275072A GB1392658A GB 1392658 A GB1392658 A GB 1392658A GB 2275072 A GB2275072 A GB 2275072A GB 2275072 A GB2275072 A GB 2275072A GB 1392658 A GB1392658 A GB 1392658A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- chloro
- prepared
- acid
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- 229940124587 cephalosporin Drugs 0.000 abstract 3
- 150000001780 cephalosporins Chemical class 0.000 abstract 3
- -1 acetoacetamido Chemical group 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XQUJVGVNTYDLIG-UHFFFAOYSA-N 2-chloro-6-fluoro-n-hydroxybenzenecarboximidoyl chloride Chemical compound ON=C(Cl)C1=C(F)C=CC=C1Cl XQUJVGVNTYDLIG-UHFFFAOYSA-N 0.000 abstract 1
- VJTMYAKRYZHPPO-UHFFFAOYSA-N 2-chloro-6-fluorobenzonitrile oxide Chemical compound [O-][N+]#CC1=C(F)C=CC=C1Cl VJTMYAKRYZHPPO-UHFFFAOYSA-N 0.000 abstract 1
- HIPCWHZXBUDQJH-UHFFFAOYSA-N 2-chlorobenzonitrile oxide Chemical compound [O-][N+]#CC1=CC=CC=C1Cl HIPCWHZXBUDQJH-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- WASQWSOJHCZDFK-UHFFFAOYSA-N diketene Chemical compound C=C1CC(=O)O1 WASQWSOJHCZDFK-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/02—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2275072A GB1392658A (en) | 1972-05-15 | 1972-05-15 | Preparation of beta-lactamic antibiotics |
| ZA732952A ZA732952B (en) | 1972-05-15 | 1973-05-01 | Process for the preparation of antibiotics |
| AU55424/73A AU5542473A (en) | 1972-05-15 | 1973-05-08 | Isoxazolyl penicillins and cephalosporins isoxazolyl penicillins and cephalosporins |
| DE2323809A DE2323809A1 (de) | 1972-05-15 | 1973-05-11 | Beta-lactamische antibiotica und verfahren zu ihrer herstellung |
| ES414747A ES414747A1 (es) | 1972-05-15 | 1973-05-14 | Procedimiento para la preparacion de antibioticos. |
| BE2052769A BE799468A (fr) | 1972-05-15 | 1973-05-14 | Procede de preparation d'antibiotiques, |
| AR248030A AR201000A1 (es) | 1972-05-15 | 1973-05-15 | Procedimiento para la preparacion de isoxazolil-penicilinas |
| CA171,475A CA1001614A (en) | 1972-05-15 | 1973-05-15 | Isoxazolyl penicillins and isoxazolyl cephalosoporins and their derivatives |
| AT423773A AT327379B (de) | 1972-05-15 | 1973-05-15 | Verfahren zur herstellung von isoxazolyl-beta-lactam-antibiotika |
| NL7306720A NL7306720A (enrdf_load_stackoverflow) | 1972-05-15 | 1973-05-15 | |
| JP48054008A JPS4961191A (enrdf_load_stackoverflow) | 1972-05-15 | 1973-05-15 | |
| FR7317505A FR2184851B1 (enrdf_load_stackoverflow) | 1972-05-15 | 1973-05-15 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2275072A GB1392658A (en) | 1972-05-15 | 1972-05-15 | Preparation of beta-lactamic antibiotics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1392658A true GB1392658A (en) | 1975-04-30 |
Family
ID=10184484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2275072A Expired GB1392658A (en) | 1972-05-15 | 1972-05-15 | Preparation of beta-lactamic antibiotics |
Country Status (12)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2221801C1 (ru) * | 2002-06-10 | 2004-01-20 | Савельев Евгений Александрович | Способ получения натриевой соли 6-(3-фенил-5-метилизоксазол-4-карбамино)-пенициллановой кислоты |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1382596A (en) * | 1971-06-15 | 1975-02-05 | Koninklijke Gist Spiritus | Penicillin and cephalosporin compounds |
-
1972
- 1972-05-15 GB GB2275072A patent/GB1392658A/en not_active Expired
-
1973
- 1973-05-01 ZA ZA732952A patent/ZA732952B/xx unknown
- 1973-05-08 AU AU55424/73A patent/AU5542473A/en not_active Expired
- 1973-05-11 DE DE2323809A patent/DE2323809A1/de active Pending
- 1973-05-14 BE BE2052769A patent/BE799468A/xx unknown
- 1973-05-14 ES ES414747A patent/ES414747A1/es not_active Expired
- 1973-05-15 NL NL7306720A patent/NL7306720A/xx not_active Application Discontinuation
- 1973-05-15 FR FR7317505A patent/FR2184851B1/fr not_active Expired
- 1973-05-15 AR AR248030A patent/AR201000A1/es active
- 1973-05-15 AT AT423773A patent/AT327379B/de active
- 1973-05-15 CA CA171,475A patent/CA1001614A/en not_active Expired
- 1973-05-15 JP JP48054008A patent/JPS4961191A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2221801C1 (ru) * | 2002-06-10 | 2004-01-20 | Савельев Евгений Александрович | Способ получения натриевой соли 6-(3-фенил-5-метилизоксазол-4-карбамино)-пенициллановой кислоты |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4961191A (enrdf_load_stackoverflow) | 1974-06-13 |
| DE2323809A1 (de) | 1973-11-29 |
| ZA732952B (en) | 1974-04-24 |
| AR201000A1 (es) | 1975-02-06 |
| FR2184851B1 (enrdf_load_stackoverflow) | 1977-07-29 |
| NL7306720A (enrdf_load_stackoverflow) | 1973-11-19 |
| AT327379B (de) | 1976-01-26 |
| ES414747A1 (es) | 1976-02-01 |
| ATA423773A (de) | 1975-04-15 |
| BE799468A (fr) | 1973-08-31 |
| CA1001614A (en) | 1976-12-14 |
| AU5542473A (en) | 1974-11-14 |
| FR2184851A1 (enrdf_load_stackoverflow) | 1973-12-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |