GB1389509A - Dihydropyridinepolyesters their production and their medicinal use - Google Patents
Dihydropyridinepolyesters their production and their medicinal useInfo
- Publication number
- GB1389509A GB1389509A GB4548173A GB4548173A GB1389509A GB 1389509 A GB1389509 A GB 1389509A GB 4548173 A GB4548173 A GB 4548173A GB 4548173 A GB4548173 A GB 4548173A GB 1389509 A GB1389509 A GB 1389509A
- Authority
- GB
- United Kingdom
- Prior art keywords
- radical
- alkyl
- reacted
- compound
- aldehyde
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722248150 DE2248150A1 (de) | 1972-09-30 | 1972-09-30 | Dihydropyridinpolyester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1389509A true GB1389509A (en) | 1975-04-03 |
Family
ID=5857927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4548173A Expired GB1389509A (en) | 1972-09-30 | 1973-09-28 | Dihydropyridinepolyesters their production and their medicinal use |
Country Status (22)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0206747A2 (en) | 1985-06-17 | 1986-12-30 | Warner-Lambert Company | 1,4-Dihydropyridine derivatives useful in the treatment of cardiovascular disorders, and a process for producing the derivatives |
| US4732898A (en) * | 1986-04-29 | 1988-03-22 | Warner-Lambert Company | 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3970662A (en) * | 1975-06-19 | 1976-07-20 | Sterling Drug Inc. | 4-(3-Nitrophenyl)-2,3,5,6-pyridinetetracarboxylic acid and intermediates |
| DK152285C (da) * | 1975-07-02 | 1988-10-10 | Fujisawa Pharmaceutical Co | Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater |
| GB1591089A (en) * | 1976-12-17 | 1981-06-10 | Fujisawa Pharmaceutical Co | 1,4-dihydropyridine derivatives and process for preparation thereof |
| US4338322A (en) * | 1975-07-02 | 1982-07-06 | Fujisawa Pharmaceutical Co., Ltd. | 1,4-Dihydropyridine derivatives, pharmaceutical compositions containing same and methods of effecting vasodilation using same |
| FR2320750A1 (fr) * | 1975-08-12 | 1977-03-11 | Hexachimie | Dihydro-1,4 pyridines et leur application therapeutique |
| US4055588A (en) * | 1976-02-20 | 1977-10-25 | Sterling Drug Inc. | Tetra-(lower-alkyl)3-(3-nitrophenyl)-1,5-pentanedione-1,2,4,5-tetracarboxylates |
| DE2837477A1 (de) * | 1978-08-28 | 1980-03-13 | Bayer Ag | Sila-substituierte 1,4-dihydropyridin- derivate |
| DE3022002A1 (de) * | 1980-06-12 | 1981-12-17 | Bayer Ag, 5090 Leverkusen | 1,4-dihydropyridin-4-carbonsaeureamide, verfahren zu deren herstellung, sowie diese enthaltende arzneimittel |
| CS228917B2 (en) | 1981-03-14 | 1984-05-14 | Pfizer | Method of preparing substituted derivatives of 1,4-dihydropyridine |
| US4497808A (en) * | 1981-12-30 | 1985-02-05 | Ciba-Geigy Corporation | N-Oxide compounds useful in the treatment of cardiovascular ailments |
| DE3363743D1 (en) * | 1982-07-22 | 1986-07-03 | Pfizer Ltd | Dihydropyridine anti-ischaemic and antihypertensive agents |
| PH19166A (en) * | 1982-09-04 | 1986-01-16 | Pfizer | Dihydropyridined,pharmaceutical compositions and method of use |
| EP0107293A3 (en) * | 1982-09-04 | 1984-06-06 | Pfizer Limited | Dihydropyridines |
| US4515799A (en) * | 1983-02-02 | 1985-05-07 | Pfizer Inc. | Dihydropyridine anti-ischaemic and antihypertensive agents |
| JPS59144249U (ja) * | 1983-03-16 | 1984-09-27 | 株式会社御田釦製作所 | 紐類の端末処理具 |
| EP0125803A3 (en) * | 1983-04-27 | 1987-01-21 | FISONS plc | Pharmaceutically active dihydropyridines |
| US4678796A (en) * | 1984-11-30 | 1987-07-07 | Warner-Lambert Company | 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders |
| DE3629545A1 (de) * | 1986-08-30 | 1988-03-10 | Bayer Ag | Dihydropyridinverbindungen, verfahren zu ihrer herstellung und ihre verwendung |
| JPH0688973B2 (ja) * | 1987-03-12 | 1994-11-09 | 京都薬品工業株式会社 | １，４−ジヒドロピリジン誘導体 |
| US6653481B2 (en) * | 2000-12-29 | 2003-11-25 | Synthon Bv | Process for making amlodipine |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
| DE2117572C3 (de) * | 1971-04-10 | 1980-03-20 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin ^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
-
1972
- 1972-09-30 DE DE19722248150 patent/DE2248150A1/de active Pending
-
1973
- 1973-09-24 US US399850A patent/US3905983A/en not_active Expired - Lifetime
- 1973-09-25 CA CA181,860A patent/CA1005061A/en not_active Expired
- 1973-09-26 IL IL7343329A patent/IL43329A/en unknown
- 1973-09-26 AU AU60716/73A patent/AU476129B2/en not_active Expired
- 1973-09-27 DD DD173732A patent/DD110659A5/xx unknown
- 1973-09-28 CH CH1390273A patent/CH583703A5/xx not_active IP Right Cessation
- 1973-09-28 NL NL7313422A patent/NL7313422A/xx not_active Application Discontinuation
- 1973-09-28 CH CH1113776A patent/CH605752A5/xx not_active IP Right Cessation
- 1973-09-28 IE IE1735/73A patent/IE38335B1/xx unknown
- 1973-09-28 AT AT834773A patent/AT330175B/de active
- 1973-09-28 GB GB4548173A patent/GB1389509A/en not_active Expired
- 1973-09-28 DK DK533473A patent/DK137722C/da active
- 1973-09-28 ZA ZA737659*A patent/ZA737659B/xx unknown
- 1973-09-28 FR FR7334944A patent/FR2201095B1/fr not_active Expired
- 1973-09-28 BE BE136158A patent/BE805451A/xx unknown
- 1973-09-28 JP JP10862773A patent/JPS5647905B2/ja not_active Expired
- 1973-09-28 HU HUBA2984A patent/HU166357B/hu unknown
- 1973-09-28 LU LU68530A patent/LU68530A1/xx unknown
- 1973-09-29 PL PL1973182553A patent/PL92079B1/pl unknown
- 1973-09-29 PL PL1973182552A patent/PL92084B1/pl unknown
- 1973-09-29 PL PL1973165524A patent/PL91085B1/pl unknown
- 1973-09-29 ES ES419193A patent/ES419193A1/es not_active Expired
- 1973-10-01 SE SE7313187A patent/SE403777B/xx unknown
- 1973-10-01 CS CS5596A patent/CS178440B2/cs unknown
- 1973-10-01 CS CS6765A patent/CS178435B2/cs unknown
- 1973-10-01 CS CS5597A patent/CS178441B2/cs unknown
-
1975
- 1975-12-16 ES ES443521A patent/ES443521A1/es not_active Expired
- 1975-12-16 ES ES443522A patent/ES443522A1/es not_active Expired
-
1977
- 1977-09-28 CH CH538177A patent/CH601233A5/xx not_active IP Right Cessation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0206747A2 (en) | 1985-06-17 | 1986-12-30 | Warner-Lambert Company | 1,4-Dihydropyridine derivatives useful in the treatment of cardiovascular disorders, and a process for producing the derivatives |
| US4732898A (en) * | 1986-04-29 | 1988-03-22 | Warner-Lambert Company | 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1389509A (en) | Dihydropyridinepolyesters their production and their medicinal use | |
| ATE314347T1 (de) | Sulfonylderivate | |
| GB1384031A (en) | N-substituted dihydropyridine compounds their production and their medicinal use | |
| GB1477114A (en) | 1,4-dihydropyridinecarboxylic acid aralkyl esters processes for their preparation and their use as medicaments | |
| ES401614A1 (es) | Procedimiento para la obtencion de 1,4-dihidro - piridin- carboxilatos asimetricos. | |
| GB1383625A (en) | 1,4-dihydropyridine carboxylic acid compounds their production and their medicinal use | |
| GB1173104A (en) | 0,4-Dihydropyridine Derivatives and their production | |
| KR850004463A (ko) | 디히드로피리딘 유도체의 제조방법 | |
| GB1384504A (en) | Bridgeheadheterocyclic compounds their production and their medicinal use | |
| GB1369401A (en) | Process for the manufacture of 2-amino-1,4-dihydropyridines and their use as coronary agents | |
| GB1389504A (en) | 2-amino-1,4-dihydropyridines their production and their medicinal use | |
| FI842911A0 (fi) | Dihydropyridiner som motverkar lokal blodbrist och foerhoejt tryck. | |
| GB1389505A (en) | 3,4-dihydropyridones their production and their medicinal use | |
| ES453162A1 (es) | Un procedimiento para la obtencion de compuestos heteroci- clicos. | |
| ES8504771A1 (es) | Un procedimiento para preparar derivados de piridina | |
| GB1379005A (en) | 2,6-diaminodihydropyridines their production and their medicinal use | |
| GB1437896A (en) | Substituted thiazole-2-carboxylic amides and process for the preparation thereof | |
| GB1430926A (en) | 2-amino-3,4-dihydropyridines their production and their medicinal use | |
| GB1353508A (en) | Aminoisoquinolines | |
| EP0190364A4 (en) | 1,4-DIHYDROPYRIDINE-3,5-DIKARBOXYLATE BODIES. | |
| IE37367B1 (en) | New substituted 4,5-dihydropyridines their production and their medicinal use | |
| GB1421305A (en) | 1,4-dihydroquinoline derivatives their production and their medicinal use | |
| GB1444879A (en) | 3-acylamino-6-amino-3,4-dihydro-2-pyridones and their use as medicaments | |
| IE38064B1 (en) | New 2-amino-4h-pyrane compounds their production and their medicinal use | |
| GB1463582A (en) | Pyridine derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |