GB1389033A - Cardenolide- and buadienolide-glycosides and process for their preparation - Google Patents
Cardenolide- and buadienolide-glycosides and process for their preparationInfo
- Publication number
- GB1389033A GB1389033A GB3325672A GB3325672A GB1389033A GB 1389033 A GB1389033 A GB 1389033A GB 3325672 A GB3325672 A GB 3325672A GB 3325672 A GB3325672 A GB 3325672A GB 1389033 A GB1389033 A GB 1389033A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- cardenolide
- preparation
- koenigs
- july
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000006994 Koenigs-Knorr glycosidation reaction Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000010931 ester hydrolysis Methods 0.000 abstract 2
- 239000004593 Epoxy Substances 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 229940097217 cardiac glycoside Drugs 0.000 abstract 1
- 239000002368 cardiac glycoside Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229930002534 steroid glycoside Natural products 0.000 abstract 1
- 150000008143 steroidal glycosides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2136654A DE2136654A1 (de) | 1971-07-22 | 1971-07-22 | 14,15 beta-epoxycardenolid- und 14,15 beta-epoxybufadienolid-glykoside und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1389033A true GB1389033A (en) | 1975-04-03 |
Family
ID=5814458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3325672A Expired GB1389033A (en) | 1971-07-22 | 1972-07-17 | Cardenolide- and buadienolide-glycosides and process for their preparation |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3919191A (enExample) |
| AR (1) | AR194257A1 (enExample) |
| AT (1) | AT332565B (enExample) |
| AU (1) | AU4474772A (enExample) |
| BE (1) | BE786645A (enExample) |
| CA (1) | CA977334A (enExample) |
| CH (1) | CH574975A5 (enExample) |
| DD (1) | DD97417A5 (enExample) |
| DE (1) | DE2136654A1 (enExample) |
| ES (1) | ES404915A1 (enExample) |
| FR (1) | FR2146475B1 (enExample) |
| GB (1) | GB1389033A (enExample) |
| HU (1) | HU163556B (enExample) |
| IE (1) | IE36579B1 (enExample) |
| IL (1) | IL39945A0 (enExample) |
| NL (1) | NL7209860A (enExample) |
| ZA (1) | ZA725058B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2841074A1 (de) * | 1978-09-21 | 1980-04-03 | Basf Ag | 4,5-methano-bufadienolid-rhamnoside, verfahren zu deren herstellung und diese enthaltende arzneimittel |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH421093A (de) * | 1962-04-11 | 1966-09-30 | Sandoz Ag | Verfahren zur Herstellung von neuen Steroiden |
| US3398138A (en) * | 1966-05-24 | 1968-08-20 | American Home Prod | Novel cardenolides and derivatives |
| DE1812946C3 (de) * | 1968-12-05 | 1978-11-02 | Hoechst Ag, 6000 Frankfurt | Herzwirksame 14beta, lSbeta Oxidobutatrienolide und Verfahren zu ihrer Herstellung |
| US3585186A (en) * | 1969-01-31 | 1971-06-15 | American Cyanamid Co | Preparation of glycopyranosiduronides and glycopyranosides and products resulting therefrom |
-
0
- BE BE786645D patent/BE786645A/xx unknown
-
1971
- 1971-07-22 DE DE2136654A patent/DE2136654A1/de active Pending
-
1972
- 1972-07-10 CA CA146,694A patent/CA977334A/en not_active Expired
- 1972-07-15 ES ES404915A patent/ES404915A1/es not_active Expired
- 1972-07-17 NL NL7209860A patent/NL7209860A/xx unknown
- 1972-07-17 GB GB3325672A patent/GB1389033A/en not_active Expired
- 1972-07-19 DD DD164529A patent/DD97417A5/xx unknown
- 1972-07-19 IL IL39945A patent/IL39945A0/xx unknown
- 1972-07-19 CH CH1079872A patent/CH574975A5/xx not_active IP Right Cessation
- 1972-07-20 AU AU44747/72A patent/AU4474772A/en not_active Expired
- 1972-07-20 AR AR243166A patent/AR194257A1/es active
- 1972-07-21 AT AT630472A patent/AT332565B/de not_active IP Right Cessation
- 1972-07-21 ZA ZA725058A patent/ZA725058B/xx unknown
- 1972-07-21 IE IE1020/72A patent/IE36579B1/xx unknown
- 1972-07-21 FR FR7226394A patent/FR2146475B1/fr not_active Expired
- 1972-07-21 HU HUHO1501A patent/HU163556B/hu unknown
- 1972-07-21 US US274106A patent/US3919191A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IE36579B1 (en) | 1976-12-08 |
| HU163556B (enExample) | 1973-09-27 |
| IL39945A0 (en) | 1972-09-28 |
| DD97417A5 (enExample) | 1973-05-05 |
| FR2146475A1 (enExample) | 1973-03-02 |
| ES404915A1 (es) | 1975-06-16 |
| DE2136654A1 (de) | 1973-02-01 |
| US3919191A (en) | 1975-11-11 |
| AU4474772A (en) | 1974-01-24 |
| AT332565B (de) | 1976-10-11 |
| AR194257A1 (es) | 1973-06-29 |
| CA977334A (en) | 1975-11-04 |
| ATA630472A (de) | 1976-01-15 |
| BE786645A (fr) | 1973-01-24 |
| ZA725058B (en) | 1973-04-25 |
| CH574975A5 (enExample) | 1976-04-30 |
| NL7209860A (enExample) | 1973-01-24 |
| FR2146475B1 (enExample) | 1975-06-20 |
| IE36579L (en) | 1973-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |