GB1383888A - Amino ether derivatives of orthothymatic esters - Google Patents
Amino ether derivatives of orthothymatic estersInfo
- Publication number
- GB1383888A GB1383888A GB3357573A GB3357573A GB1383888A GB 1383888 A GB1383888 A GB 1383888A GB 3357573 A GB3357573 A GB 3357573A GB 3357573 A GB3357573 A GB 3357573A GB 1383888 A GB1383888 A GB 1383888A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- radical
- hydrogen
- carbon atoms
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 2
- SBOJXQVPLKSXOG-UHFFFAOYSA-N o-amino-hydroxylamine Chemical class NON SBOJXQVPLKSXOG-UHFFFAOYSA-N 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- -1 aminoalkyl halide Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002269 analeptic agent Substances 0.000 abstract 1
- 230000003555 analeptic effect Effects 0.000 abstract 1
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 230000002921 anti-spasmodic effect Effects 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 239000012374 esterification agent Substances 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- BLNWTAHYTCHDJH-UHFFFAOYSA-O hydroxy(oxo)azanium Chemical compound O[NH+]=O BLNWTAHYTCHDJH-UHFFFAOYSA-O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7226158A FR2192811B1 (enExample) | 1972-07-20 | 1972-07-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1383888A true GB1383888A (en) | 1974-02-12 |
Family
ID=9102125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3357573A Expired GB1383888A (en) | 1972-07-20 | 1973-07-13 | Amino ether derivatives of orthothymatic esters |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3906030A (enExample) |
| JP (1) | JPS5720938B2 (enExample) |
| AR (1) | AR205520A1 (enExample) |
| BE (1) | BE802066A (enExample) |
| CA (1) | CA989838A (enExample) |
| CH (1) | CH575380A5 (enExample) |
| DE (1) | DE2336670A1 (enExample) |
| ES (1) | ES417042A1 (enExample) |
| FR (1) | FR2192811B1 (enExample) |
| GB (1) | GB1383888A (enExample) |
| ZA (1) | ZA734675B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54119428A (en) * | 1978-02-24 | 1979-09-17 | Hisamitsu Pharmaceut Co Inc | Novel benzoic acid derivative |
| FR2581643B1 (fr) * | 1985-05-10 | 1988-11-18 | Irceba | Compositions pharmaceutiques utiles dans le domaine de l'urologie, contenant de l'acetoxy-1 methyl-2 ((piperidino)-2 ethoxy)-4 (methyl-1 ethyl)-5 benzene ou l'un de ses sels |
| FR2614302B2 (fr) * | 1986-02-10 | 1989-07-28 | Irceba | Derives du ((pyrrolidinul-1)-2 ethoxy)-5 p-cymene, procede pour leur preparation et medicaments en contenant. |
| FR2594122B1 (fr) * | 1986-02-10 | 1988-06-10 | Irceba | ((pyrrolidinyl-1)-2 ethyoxy)-3 p cymene, les derives acetyl, acetoxy, hydroxy dudit produit et les medicaments contenant lesdits composes comme principe actif |
| FR2595357B1 (fr) * | 1986-03-04 | 1988-07-08 | Irceba | (piperidino-3 propoxy)-5 p.cymene, les derives acetyl, acetoxy et hydroxy dudit produit, les sels de ces produits, un procede de preparation desdits produits et les medicaments contenant au moins un de ces produits comme principe actif |
| ATE74600T1 (de) * | 1987-04-30 | 1992-04-15 | Inst Rech Chim Biolog | Derivate von 5-(2-(1-pyrrolidinyl)-aethoxy>-pcymen, verfahren zu ihrer herstellung und diese derivate enthaltende arzneimittel. |
| TWI356054B (en) * | 2004-03-31 | 2012-01-11 | Activus Pharma Co Ltd | Quaternary ammonium compound, producing method the |
| JP4799872B2 (ja) * | 2004-03-31 | 2011-10-26 | 株式会社アクティバスファーマ | ４級アンモニウム化合物、その製造方法及び脳血管障害治療剤 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1118219B (de) * | 1957-02-21 | 1961-11-30 | Bayer Ag | Verfahren zur Herstellung von basisch substituierten Alkylaethern von o-Kresotinsaeureestern und deren Salzen |
-
1972
- 1972-07-20 FR FR7226158A patent/FR2192811B1/fr not_active Expired
-
1973
- 1973-01-01 AR AR249155A patent/AR205520A1/es active
- 1973-07-05 CH CH983473A patent/CH575380A5/xx not_active IP Right Cessation
- 1973-07-05 US US376906A patent/US3906030A/en not_active Expired - Lifetime
- 1973-07-09 BE BE133246A patent/BE802066A/xx unknown
- 1973-07-11 ZA ZA734675A patent/ZA734675B/xx unknown
- 1973-07-13 GB GB3357573A patent/GB1383888A/en not_active Expired
- 1973-07-19 ES ES417042A patent/ES417042A1/es not_active Expired
- 1973-07-19 DE DE19732336670 patent/DE2336670A1/de not_active Withdrawn
- 1973-07-19 CA CA176,902A patent/CA989838A/en not_active Expired
- 1973-07-20 JP JP8238073A patent/JPS5720938B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA734675B (en) | 1974-06-26 |
| CH575380A5 (enExample) | 1976-05-14 |
| JPS4943936A (enExample) | 1974-04-25 |
| BE802066A (fr) | 1973-11-05 |
| CA989838A (en) | 1976-05-25 |
| US3906030A (en) | 1975-09-16 |
| AR205520A1 (es) | 1976-05-14 |
| FR2192811B1 (enExample) | 1975-08-08 |
| FR2192811A1 (enExample) | 1974-02-15 |
| DE2336670A1 (de) | 1974-01-31 |
| JPS5720938B2 (enExample) | 1982-05-04 |
| ES417042A1 (es) | 1976-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |