GB1378277A - Proteaseinhibiting substance its extraction and its use - Google Patents
Proteaseinhibiting substance its extraction and its useInfo
- Publication number
- GB1378277A GB1378277A GB1024273A GB1024273A GB1378277A GB 1378277 A GB1378277 A GB 1378277A GB 1024273 A GB1024273 A GB 1024273A GB 1024273 A GB1024273 A GB 1024273A GB 1378277 A GB1378277 A GB 1378277A
- Authority
- GB
- United Kingdom
- Prior art keywords
- product
- ammonium sulphate
- inhibitor
- solution
- resin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000126 substance Substances 0.000 title abstract 2
- 238000000605 extraction Methods 0.000 title 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 abstract 4
- 241000237369 Helix pomatia Species 0.000 abstract 2
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 abstract 2
- 108090000631 Trypsin Proteins 0.000 abstract 2
- 102000004142 Trypsin Human genes 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 2
- 239000000137 peptide hydrolase inhibitor Substances 0.000 abstract 2
- 239000011347 resin Substances 0.000 abstract 2
- 229920005989 resin Polymers 0.000 abstract 2
- 239000012588 trypsin Substances 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 108090000317 Chymotrypsin Proteins 0.000 abstract 1
- 108010088842 Fibrinolysin Proteins 0.000 abstract 1
- 108060005987 Kallikrein Proteins 0.000 abstract 1
- 102000001399 Kallikrein Human genes 0.000 abstract 1
- 206010033645 Pancreatitis Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000011149 active material Substances 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 239000003729 cation exchange resin Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229960002376 chymotrypsin Drugs 0.000 abstract 1
- 230000020764 fibrinolysis Effects 0.000 abstract 1
- 238000002523 gelfiltration Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000010253 intravenous injection Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000007791 liquid phase Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 229940012957 plasmin Drugs 0.000 abstract 1
- 239000007790 solid phase Substances 0.000 abstract 1
- 229960001322 trypsin Drugs 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2210262A DE2210262A1 (de) | 1972-03-03 | 1972-03-03 | Polyvalente proteaseninhibitorpraeparate aus helix pomatia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1378277A true GB1378277A (en) | 1974-12-27 |
Family
ID=5837811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1024273A Expired GB1378277A (en) | 1972-03-03 | 1973-03-02 | Proteaseinhibiting substance its extraction and its use |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3885012A (https=) |
| JP (1) | JPS4899384A (https=) |
| CH (1) | CH590063A5 (https=) |
| DE (1) | DE2210262A1 (https=) |
| FR (1) | FR2174925B1 (https=) |
| GB (1) | GB1378277A (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3971736A (en) * | 1975-01-21 | 1976-07-27 | Merck & Co., Inc. | Cathepsin in D inhibitors |
| DE69221686T2 (de) * | 1991-03-01 | 1998-04-02 | Atherton Investments Ltd | Therapeutische und kosmetische zusammensetzungen zur hautbehandlung |
| FR3023717B1 (fr) * | 2014-07-21 | 2017-12-08 | Pascal Drevet | Hydrolysat peptidique d'escargots, fractions peptidiques, procede de fabrication, utilisation et compositions pour inhiber l'enzyme de conversion de l'angiotensine |
-
1972
- 1972-03-03 DE DE2210262A patent/DE2210262A1/de active Pending
-
1973
- 1973-03-01 JP JP48023828A patent/JPS4899384A/ja active Pending
- 1973-03-02 GB GB1024273A patent/GB1378277A/en not_active Expired
- 1973-03-02 FR FR7307515A patent/FR2174925B1/fr not_active Expired
- 1973-03-02 US US337699A patent/US3885012A/en not_active Expired - Lifetime
- 1973-03-02 CH CH313873A patent/CH590063A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2174925B1 (https=) | 1976-12-03 |
| US3885012A (en) | 1975-05-20 |
| DE2210262A1 (de) | 1973-09-06 |
| FR2174925A1 (https=) | 1973-10-19 |
| JPS4899384A (https=) | 1973-12-15 |
| CH590063A5 (https=) | 1977-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |