GB1376588A - Piperazine derivatives - Google Patents
Piperazine derivativesInfo
- Publication number
- GB1376588A GB1376588A GB3373273A GB3373273A GB1376588A GB 1376588 A GB1376588 A GB 1376588A GB 3373273 A GB3373273 A GB 3373273A GB 3373273 A GB3373273 A GB 3373273A GB 1376588 A GB1376588 A GB 1376588A
- Authority
- GB
- United Kingdom
- Prior art keywords
- july
- halogen
- iii
- reacting
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2235597A DE2235597A1 (de) | 1972-07-20 | 1972-07-20 | 1-eckige klammer auf 3-(5,6,7,8tetrahydronaphth-1-yl-oxy) -propyl eckige klammer zu -piperazin-derivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1376588A true GB1376588A (en) | 1974-12-04 |
Family
ID=5851155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3373273A Expired GB1376588A (en) | 1972-07-20 | 1973-07-16 | Piperazine derivatives |
Country Status (14)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL175059C (nl) * | 1974-02-23 | Boehringer Mannheim Gmbh | Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten. | |
| DE2658762A1 (de) * | 1976-12-24 | 1978-06-29 | Hoechst Ag | Neue o-alkylierte oxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| GB1583372A (en) * | 1977-04-04 | 1981-01-28 | Degussa | 1-(3-(3,4,5-trimethoxyphenoxy)-2-hydroxypropyl)-4-aryl piperazine derivatives |
| US4101723A (en) * | 1977-04-05 | 1978-07-18 | E. R. Squibb & Sons, Inc. | Substituted piperazinopropanols |
| US4259327A (en) * | 1979-04-02 | 1981-03-31 | Merck & Co., Inc. | Substituted aminoalkoxypyridines, compositions and use thereof |
| US4255426A (en) * | 1979-07-09 | 1981-03-10 | Pfizer Inc. | 1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted-piperazines and piperidines |
| DE3918542A1 (de) * | 1989-06-07 | 1990-12-13 | Boehringer Mannheim Gmbh | Hydroxylierte 1-phenyl-4-(3-(napthth-1-yl-oxy)-2-hydroxy -propyl)-piperazine, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| FR2658818B1 (fr) * | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| IT1255178B (it) * | 1992-06-26 | 1995-10-20 | Pierrel Spa | N(eter0)-aril-n(etero)-tetralinalchil piperazine aventi attivita' serotoninergica,dopaminergica e adrenergica |
| CA2332275A1 (en) * | 1998-05-14 | 1999-11-18 | Zoltan Tamas Nagy | Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient |
| EP1425261A2 (de) * | 2001-08-31 | 2004-06-09 | Bayer Chemicals AG | Verfahren zur herstellung von 4-amino-1-naphtholethern |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1317034A (en) * | 1970-11-06 | 1973-05-16 | Pfizer Ltd | 1-2-hydroxy-3-phenoxy- or -phenylthiopropyl-piperazine derivatives |
-
1972
- 1972-07-20 DE DE2235597A patent/DE2235597A1/de active Pending
-
1973
- 1973-06-14 US US05/370,068 patent/US3947446A/en not_active Expired - Lifetime
- 1973-07-13 CA CA176,440A patent/CA1003836A/en not_active Expired
- 1973-07-14 ES ES416929A patent/ES416929A1/es not_active Expired
- 1973-07-16 GB GB3373273A patent/GB1376588A/en not_active Expired
- 1973-07-16 ZA ZA734811A patent/ZA734811B/xx unknown
- 1973-07-16 AR AR249099A patent/AR196775A1/es active
- 1973-07-17 CH CH1042073A patent/CH583721A5/xx not_active IP Right Cessation
- 1973-07-17 CH CH1191576A patent/CH583722A5/xx not_active IP Right Cessation
- 1973-07-18 DD DD172339A patent/DD106842A5/xx unknown
- 1973-07-19 FR FR7326491A patent/FR2193598B1/fr not_active Expired
- 1973-07-19 NL NL737310041A patent/NL149168B/xx unknown
- 1973-07-19 HU HUBO1452A patent/HU165887B/hu unknown
- 1973-07-19 AT AT636673A patent/AT330188B/de not_active IP Right Cessation
- 1973-07-20 JP JP8249373A patent/JPS5331158B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3947446A (en) | 1976-03-30 |
| FR2193598A1 (US20020167097A1-20021114-C00005.png) | 1974-02-22 |
| DD106842A5 (US20020167097A1-20021114-C00005.png) | 1974-07-05 |
| JPS4943990A (US20020167097A1-20021114-C00005.png) | 1974-04-25 |
| FR2193598B1 (US20020167097A1-20021114-C00005.png) | 1977-07-15 |
| HU165887B (US20020167097A1-20021114-C00005.png) | 1974-12-28 |
| AR196775A1 (es) | 1974-02-19 |
| ES416929A1 (es) | 1976-03-01 |
| CH583722A5 (US20020167097A1-20021114-C00005.png) | 1977-01-14 |
| AT330188B (de) | 1976-06-25 |
| ZA734811B (en) | 1974-07-31 |
| NL149168B (nl) | 1976-04-15 |
| CA1003836A (en) | 1977-01-18 |
| DE2235597A1 (de) | 1974-01-31 |
| NL7310041A (US20020167097A1-20021114-C00005.png) | 1974-01-22 |
| CH583721A5 (US20020167097A1-20021114-C00005.png) | 1977-01-14 |
| JPS5331158B2 (US20020167097A1-20021114-C00005.png) | 1978-08-31 |
| ATA636673A (de) | 1975-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |