GB1421006A - Imidazolidine derivatives - Google Patents

Imidazolidine derivatives

Info

Publication number
GB1421006A
GB1421006A GB1006173A GB1006173A GB1421006A GB 1421006 A GB1421006 A GB 1421006A GB 1006173 A GB1006173 A GB 1006173A GB 1006173 A GB1006173 A GB 1006173A GB 1421006 A GB1421006 A GB 1421006A
Authority
GB
United Kingdom
Prior art keywords
alkyl
acid addition
compounds
march
quaternary ammonium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1006173A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Publication of GB1421006A publication Critical patent/GB1421006A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1421006 Fused imidazolidines AKZO NV 1 March 1973 [7 March 1972] 10061/73 Heading C2C Compounds of the general formula (R 1,2 =H, OH, halogen, CF 3 , C 1-6 alkyl or alkoxy, C 1-8 acyloxy; R 3 =H, C 1-6 alkyl, C 7-10 aralkyl; X = O, S, NR 4 ; R 4 = H, C 1-6 alkyl) and their acid addition salts and quaternary ammonium compounds are prepared by reacting a compound of the formula or acid addition salt thereof with Y = CZ 1 Z 2 (Y = H 2 , O, S; Z 1,2 =leaving atom or group or Z 1+2 =reactive atom or group) followed by reduction when Y=O or S, and optionally followed by conversion to an acid addition salt or quaternary ammonium compound. The product or intermediate may be resolved, or an optically active starting material used. The above compounds are antidepressants, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
GB1006173A 1972-03-07 1973-03-01 Imidazolidine derivatives Expired GB1421006A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7202963A NL7202963A (en) 1972-03-07 1972-03-07

Publications (1)

Publication Number Publication Date
GB1421006A true GB1421006A (en) 1976-01-14

Family

ID=19815531

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1006173A Expired GB1421006A (en) 1972-03-07 1973-03-01 Imidazolidine derivatives

Country Status (16)

Country Link
US (1) US3860606A (en)
JP (1) JPS4899198A (en)
AR (3) AR202388A1 (en)
AT (1) AT326667B (en)
AU (1) AU471800B2 (en)
BE (1) BE796341A (en)
CA (1) CA1010032A (en)
CH (1) CH589083A5 (en)
DE (1) DE2311019A1 (en)
ES (1) ES412372A1 (en)
FR (1) FR2181796B1 (en)
GB (1) GB1421006A (en)
HU (1) HU166348B (en)
IE (1) IE37322B1 (en)
NL (1) NL7202963A (en)
ZA (1) ZA731086B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984002704A3 (en) * 1982-12-30 1984-08-02 Beecham Group Plc Tetracyclic compounds

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL178593C (en) * 1974-01-31 1986-04-16 Akzo Nv PROCESS FOR PREPARING A PHARMACEUTICAL PREPARATION BASED ON A TETRACYCLIC COMPOUND AND METHOD FOR PREPARING THE TETRACYCLIC COMPOUNDS TO BE USED THEREOF
NL7414038A (en) * 1974-10-28 1976-05-03 Akzo Nv NEW TETRACYCLIC PYRROLIDINO DERIVATIVES.
NL189199C (en) * 1975-04-05 1993-02-01 Akzo Nv PROCESS FOR THE PREPARATION OF PHARMACEUTICAL PREPARATIONS WITH ACTION ON THE CENTRAL NERVOUS SYSTEM BASED ON BENZ (ARYL) AZEPINE DERIVATIVES, THE PHARMACEUTICAL PREPARATIONS OBTAINED, AND METHOD FOR PREPARING THE PRODUCT TO BE USED.
DE3008944A1 (en) * 1980-03-08 1981-09-24 C.H. Boehringer Sohn, 6507 Ingelheim DIBENZIMIDAZOAZEPINE, THEIR PRODUCTION AND USE
DE3134672A1 (en) * 1981-09-02 1983-03-17 Boehringer Ingelheim KG, 6507 Ingelheim HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE
US4728735A (en) * 1984-10-15 1988-03-01 Merck & Co., Inc. 10,11-dihydro-dibenzo-[b,f][1,4]-thiazepin derivatives
HU195491B (en) * 1985-12-20 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for production of optically active 2-chlor-12-/3-/dimethil-amin/-2-methil-prophil/-12h-dibenzol /d,g/ /1,3,6/-diaxazocine and medical compositions containing such compounds
US5478934A (en) * 1994-11-23 1995-12-26 Yuan; Jun Certain 1-substituted aminomethyl imidazole and pyrrole derivatives: novel dopamine receptor subtype specific ligands

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3435042A (en) * 1965-03-30 1969-03-25 Colgate Palmolive Co Novel morphanthridine derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984002704A3 (en) * 1982-12-30 1984-08-02 Beecham Group Plc Tetracyclic compounds

Also Published As

Publication number Publication date
ATA203073A (en) 1975-03-15
AR203866A1 (en) 1975-10-31
ZA731086B (en) 1973-11-28
BE796341A (en) 1973-09-06
US3860606A (en) 1975-01-14
IE37322L (en) 1973-09-07
CA1010032A (en) 1977-05-10
NL7202963A (en) 1973-09-11
IE37322B1 (en) 1977-06-22
CH589083A5 (en) 1977-06-30
HU166348B (en) 1975-03-28
FR2181796A1 (en) 1973-12-07
FR2181796B1 (en) 1976-10-22
AR202429A1 (en) 1975-06-06
AU471800B2 (en) 1976-05-06
AR202388A1 (en) 1975-06-06
JPS4899198A (en) 1973-12-15
ES412372A1 (en) 1976-05-01
AU5230373A (en) 1974-08-22
AT326667B (en) 1975-12-29
DE2311019A1 (en) 1973-09-20

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee