GB1375770A - - Google Patents
Info
- Publication number
- GB1375770A GB1375770A GB4461672A GB4461672A GB1375770A GB 1375770 A GB1375770 A GB 1375770A GB 4461672 A GB4461672 A GB 4461672A GB 4461672 A GB4461672 A GB 4461672A GB 1375770 A GB1375770 A GB 1375770A
- Authority
- GB
- United Kingdom
- Prior art keywords
- diacylate
- acetonide
- compounds
- give
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 1
- 229910004373 HOAc Inorganic materials 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal acetate Chemical class 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 229960001347 fluocinolone acetonide Drugs 0.000 abstract 1
- FEBLZLNTKCEFIT-VSXGLTOVSA-N fluocinolone acetonide Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O FEBLZLNTKCEFIT-VSXGLTOVSA-N 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000005907 ketalization reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 150000003116 prednisolone derivatives Chemical class 0.000 abstract 1
- 230000035484 reaction time Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229960002117 triamcinolone acetonide Drugs 0.000 abstract 1
- YNDXUCZADRHECN-JNQJZLCISA-N triamcinolone acetonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O YNDXUCZADRHECN-JNQJZLCISA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1022672A CH578590A5 (US06826419-20041130-M00005.png) | 1972-07-07 | 1972-07-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1375770A true GB1375770A (US06826419-20041130-M00005.png) | 1974-11-27 |
Family
ID=4360817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4461672A Expired GB1375770A (US06826419-20041130-M00005.png) | 1972-07-07 | 1972-09-27 |
Country Status (14)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101348516B (zh) * | 2008-09-08 | 2010-08-18 | 天津太平洋化学制药有限公司 | 曲安奈德原料药精制的工艺 |
| CN112358521A (zh) * | 2019-10-15 | 2021-02-12 | 河南利华制药有限公司 | 一种利用切向流管式反应器合成倍他米松的生产工艺 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57147859U (US06826419-20041130-M00005.png) * | 1981-03-13 | 1982-09-17 | ||
| JPS592744U (ja) * | 1982-06-25 | 1984-01-09 | 日本ビクター株式会社 | テ−プ巻取機構 |
| JPS5918720U (ja) * | 1982-07-27 | 1984-02-04 | 株式会社都島鉄工所 | コンベアにおける被搬送物の反転倒伏装置 |
| JPS6296013U (US06826419-20041130-M00005.png) * | 1985-12-06 | 1987-06-19 | ||
| DE102005009194B4 (de) * | 2005-03-01 | 2006-12-14 | Hpp-Hommel Pharmaceuticals Production Gmbh | Verfahren zur Herstellung von polymorph stabilem Triamcinolonacetonid |
-
0
- BE BE789387D patent/BE789387A/xx unknown
-
1972
- 1972-07-07 CH CH1022672A patent/CH578590A5/xx not_active IP Right Cessation
- 1972-08-16 NL NL727211172A patent/NL155267B/xx not_active IP Right Cessation
- 1972-08-23 JP JP8439472A patent/JPS5327275B2/ja not_active Expired
- 1972-09-04 SE SE7211425A patent/SE385589B/xx unknown
- 1972-09-04 DK DK435672AA patent/DK129039B/da unknown
- 1972-09-05 DE DE2243480A patent/DE2243480A1/de not_active Ceased
- 1972-09-06 AU AU46359/72A patent/AU475485B2/en not_active Expired
- 1972-09-26 ZA ZA726559A patent/ZA726559B/xx unknown
- 1972-09-27 GB GB4461672A patent/GB1375770A/en not_active Expired
- 1972-11-02 FR FR7238763A patent/FR2192557A5/fr not_active Expired
- 1972-12-29 PH PH14215A patent/PH12606A/en unknown
-
1973
- 1973-01-24 CA CA161,978A patent/CA998665A/en not_active Expired
- 1973-03-02 AT AT187873A patent/AT337370B/de not_active IP Right Cessation
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101348516B (zh) * | 2008-09-08 | 2010-08-18 | 天津太平洋化学制药有限公司 | 曲安奈德原料药精制的工艺 |
| CN112358521A (zh) * | 2019-10-15 | 2021-02-12 | 河南利华制药有限公司 | 一种利用切向流管式反应器合成倍他米松的生产工艺 |
| CN112358521B (zh) * | 2019-10-15 | 2022-02-01 | 河南利华制药有限公司 | 一种利用切向流管式反应器合成倍他米松的生产工艺 |
Also Published As
| Publication number | Publication date |
|---|---|
| SE385589B (sv) | 1976-07-12 |
| DK129039B (da) | 1974-08-12 |
| AT337370B (de) | 1977-06-27 |
| CH578590A5 (US06826419-20041130-M00005.png) | 1976-08-13 |
| JPS5327275B2 (US06826419-20041130-M00005.png) | 1978-08-07 |
| BE789387A (fr) | 1973-01-15 |
| ATA187873A (de) | 1975-11-15 |
| JPS4935382A (US06826419-20041130-M00005.png) | 1974-04-01 |
| FR2192557A5 (US06826419-20041130-M00005.png) | 1974-02-08 |
| PH12606A (en) | 1979-06-27 |
| CA998665A (en) | 1976-10-19 |
| AU475485B2 (en) | 1976-08-26 |
| NL155267B (nl) | 1977-12-15 |
| NL7211172A (US06826419-20041130-M00005.png) | 1974-01-09 |
| AU4635972A (en) | 1974-03-14 |
| ZA726559B (en) | 1973-07-25 |
| DE2243480A1 (de) | 1974-01-24 |
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| GB1375770A (US06826419-20041130-M00005.png) | ||
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 414F | Notice of opposition given (sect. 14/1949) | ||
| 414B | Case decided by the comptroller ** grants allowed (sect. 14/1949) | ||
| PS | Patent sealed [section 19, patents act 1949] | ||
| 732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |