GB1374365A - Nitrosourea derivatives - Google Patents
Nitrosourea derivativesInfo
- Publication number
- GB1374365A GB1374365A GB2814372A GB2814372A GB1374365A GB 1374365 A GB1374365 A GB 1374365A GB 2814372 A GB2814372 A GB 2814372A GB 2814372 A GB2814372 A GB 2814372A GB 1374365 A GB1374365 A GB 1374365A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- nitrosoureas
- june
- prepared
- nitrosourea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OSTGTTZJOCZWJG-UHFFFAOYSA-N nitrosourea Chemical class NC(=O)N=NO OSTGTTZJOCZWJG-UHFFFAOYSA-N 0.000 title abstract 2
- 229940045719 antineoplastic alkylating agent nitrosoureas Drugs 0.000 abstract 2
- 235000013877 carbamide Nutrition 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 230000009935 nitrosation Effects 0.000 abstract 1
- 238000007034 nitrosation reaction Methods 0.000 abstract 1
- 125000000018 nitroso group Chemical group N(=O)* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003672 ureas Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/02—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4695571A JPS5314557B1 (enExample) | 1971-06-28 | 1971-06-28 | |
| JP4249672A JPS491583A (enExample) | 1972-04-27 | 1972-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1374365A true GB1374365A (en) | 1974-11-20 |
Family
ID=26382201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2814372A Expired GB1374365A (en) | 1971-06-28 | 1972-06-15 | Nitrosourea derivatives |
Country Status (14)
| Country | Link |
|---|---|
| AT (1) | AT331808B (enExample) |
| AU (1) | AU463370B2 (enExample) |
| BE (1) | BE785481A (enExample) |
| CA (1) | CA979446A (enExample) |
| CH (1) | CH589630A5 (enExample) |
| DE (1) | DE2230003A1 (enExample) |
| DK (1) | DK133464B (enExample) |
| ES (1) | ES404315A1 (enExample) |
| FI (1) | FI55332C (enExample) |
| FR (1) | FR2147952B1 (enExample) |
| GB (1) | GB1374365A (enExample) |
| NL (1) | NL7208439A (enExample) |
| NO (1) | NO138767C (enExample) |
| SE (1) | SE384210B (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006134385A3 (en) * | 2005-06-15 | 2007-03-22 | Cambridge Entpr Ltd | Anti-inflammatory agents |
| US7662967B2 (en) | 2007-08-02 | 2010-02-16 | Cambridge Enterprise Limited | Anti-inflammatory compounds and compositions |
| US8389279B2 (en) | 2004-09-02 | 2013-03-05 | Cambridge Enterprise Limited | α-aminocyclolactam ligands for G-protein coupled receptors, and methods of using same |
| RU2483730C2 (ru) * | 2007-08-02 | 2013-06-10 | Кембридж Энтерпрайз Лимитед | Противовоспалительная композиция |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2845574A1 (de) * | 1978-10-19 | 1980-04-24 | Deutsches Krebsforsch | Durch heterocyclische ringe oder alkylreste substituierte analoga von ccnu und verfahren zu deren herstellung |
-
1972
- 1972-06-12 CA CA144,399A patent/CA979446A/en not_active Expired
- 1972-06-15 AU AU43476/72A patent/AU463370B2/en not_active Expired
- 1972-06-15 GB GB2814372A patent/GB1374365A/en not_active Expired
- 1972-06-20 DE DE19722230003 patent/DE2230003A1/de active Pending
- 1972-06-20 NL NL7208439A patent/NL7208439A/xx not_active Application Discontinuation
- 1972-06-21 CH CH934672A patent/CH589630A5/xx not_active IP Right Cessation
- 1972-06-26 AT AT548472A patent/AT331808B/de not_active IP Right Cessation
- 1972-06-26 FR FR7223047A patent/FR2147952B1/fr not_active Expired
- 1972-06-27 BE BE785481A patent/BE785481A/xx unknown
- 1972-06-27 SE SE841572A patent/SE384210B/xx unknown
- 1972-06-27 ES ES404315A patent/ES404315A1/es not_active Expired
- 1972-06-27 DK DK320872A patent/DK133464B/da unknown
- 1972-06-27 NO NO228772A patent/NO138767C/no unknown
- 1972-06-27 FI FI182672A patent/FI55332C/fi active
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8389279B2 (en) | 2004-09-02 | 2013-03-05 | Cambridge Enterprise Limited | α-aminocyclolactam ligands for G-protein coupled receptors, and methods of using same |
| WO2006134385A3 (en) * | 2005-06-15 | 2007-03-22 | Cambridge Entpr Ltd | Anti-inflammatory agents |
| EP2366391A3 (en) * | 2005-06-15 | 2011-09-28 | Cambridge Enterprise Ltd. | Anti-inflammatory agents |
| CN101227901B (zh) * | 2005-06-15 | 2014-03-05 | 剑桥企业有限公司 | 抗炎药 |
| US7662967B2 (en) | 2007-08-02 | 2010-02-16 | Cambridge Enterprise Limited | Anti-inflammatory compounds and compositions |
| US7897620B2 (en) | 2007-08-02 | 2011-03-01 | Cambridge Enterprise Limited | Methods of using anti-inflammatory compounds |
| RU2483730C2 (ru) * | 2007-08-02 | 2013-06-10 | Кембридж Энтерпрайз Лимитед | Противовоспалительная композиция |
| US8853200B2 (en) | 2007-08-02 | 2014-10-07 | Cambridge Enterprise Limited | Treatment of rheumatoid arthritis with 3-amino lactam compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2147952B1 (enExample) | 1976-03-05 |
| CA979446A (en) | 1975-12-09 |
| BE785481A (fr) | 1972-10-16 |
| DK133464B (da) | 1976-05-24 |
| ES404315A1 (es) | 1975-12-16 |
| DK133464C (enExample) | 1976-10-11 |
| AU463370B2 (en) | 1975-07-07 |
| FR2147952A1 (enExample) | 1973-03-11 |
| CH589630A5 (enExample) | 1977-07-15 |
| AU4347672A (en) | 1973-12-20 |
| DE2230003A1 (de) | 1973-01-18 |
| FI55332C (fi) | 1979-07-10 |
| AT331808B (de) | 1976-08-25 |
| NL7208439A (enExample) | 1973-01-02 |
| NO138767B (no) | 1978-07-31 |
| ATA548472A (de) | 1975-12-15 |
| FI55332B (fi) | 1979-03-30 |
| NO138767C (no) | 1978-11-08 |
| SE384210B (sv) | 1976-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |