GB1369543A - Indenylalkanoic acid compounds - Google Patents
Indenylalkanoic acid compoundsInfo
- Publication number
- GB1369543A GB1369543A GB219472A GB219472A GB1369543A GB 1369543 A GB1369543 A GB 1369543A GB 219472 A GB219472 A GB 219472A GB 219472 A GB219472 A GB 219472A GB 1369543 A GB1369543 A GB 1369543A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cis
- hydroxy
- alkyl
- difluoro
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/455—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation with carboxylic acids or their derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10863171A | 1971-01-21 | 1971-01-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1369543A true GB1369543A (en) | 1974-10-09 |
Family
ID=22323260
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB219472A Expired GB1369543A (en) | 1971-01-21 | 1972-01-17 | Indenylalkanoic acid compounds |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3737455A (cg-RX-API-DMAC7.html) |
| AU (1) | AU470524B2 (cg-RX-API-DMAC7.html) |
| CH (1) | CH579036A5 (cg-RX-API-DMAC7.html) |
| DE (1) | DE2202728A1 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2122587B1 (cg-RX-API-DMAC7.html) |
| GB (1) | GB1369543A (cg-RX-API-DMAC7.html) |
| NL (1) | NL7200062A (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3981872A (en) * | 1972-10-06 | 1976-09-21 | A. Christiaens Societe Anonyme | Derivatives of 2-amino-(1,2,3,4-tetrahydronaphthalene) |
| US3923859A (en) * | 1973-08-31 | 1975-12-02 | Merck & Co Inc | Substituted fulvene acetic acids and derivatives |
| US3869507A (en) * | 1973-10-03 | 1975-03-04 | Merck & Co Inc | Preparation of 5-fluoro-2-methyl-1-(p-methylsulfinylbenzylidene)-indenyl-3-acetic acid |
| US4656190A (en) * | 1983-11-14 | 1987-04-07 | Merck & Co., Inc. | Indene derivatives and their use as PAF-antagonists |
| EP0405602A1 (en) * | 1989-06-30 | 1991-01-02 | Laboratorios Vinas S.A. | New Zinc derivatives of anti-inflammatory drugs having improved therapeutic activity |
| US5093356A (en) * | 1990-01-16 | 1992-03-03 | Merck Frosst Canada, Inc. | Indenyl hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase |
| FI942059L (fi) * | 1991-11-05 | 1994-07-04 | Smithkline Beecham Corp | Endoteliinireseptoreiden antagonisteja |
| US5817693A (en) * | 1991-11-05 | 1998-10-06 | Cousins; Russell Donovan | Endothelin receptor antagonists |
| DK0699069T3 (da) * | 1993-04-27 | 2002-05-27 | Smithkline Beecham Corp | Endothelinreceptorantagonister |
| US6121321A (en) * | 1996-06-13 | 2000-09-19 | Cell Pathways, Inc. | Substituted methoxy benzylidene indenyl acetic and propionic acids for treating patients with precancerous lesions |
| US5998477A (en) * | 1996-06-13 | 1999-12-07 | Cell Pathways Inc. | Substituted methoxy benzylidene indenyl-acetic and propionic acids for treating patients with precancerous lesions |
| US6063818A (en) * | 1996-06-13 | 2000-05-16 | Cell Pathways Inc. | Substituted benzylidene indenyl formamides, acetamides and propionamides |
| US5965619A (en) * | 1996-06-13 | 1999-10-12 | Cell Pathways Inc. | Method for treating patients having precancerous lesions with substituted indene derivatives |
| US5948779A (en) * | 1997-12-12 | 1999-09-07 | Cell Pathways, Inc. | Substituted condensation products of n-benzyl-3-indenyl acetamides with heterocyclic aldehydes |
| US6028116A (en) * | 1998-04-03 | 2000-02-22 | Cell Pathways, Inc. | Substituted condensation products of 1H-indenyl-hydroxyalkanes with aldehydes for neoplasia |
| US6479493B1 (en) | 2001-08-23 | 2002-11-12 | Cell Pathways, Inc. | Methods for treatment of type I diabetes |
| BRPI0419048A (pt) * | 2004-09-14 | 2007-12-11 | Millennium Chemicals Inc | composição útil para fornecer revestimento de remoção de nox sobre a superfìcie material |
-
1971
- 1971-01-21 US US00108631A patent/US3737455A/en not_active Expired - Lifetime
-
1972
- 1972-01-04 NL NL7200062A patent/NL7200062A/xx not_active Application Discontinuation
- 1972-01-11 AU AU37793/72A patent/AU470524B2/en not_active Expired
- 1972-01-11 CH CH37372A patent/CH579036A5/xx not_active IP Right Cessation
- 1972-01-17 GB GB219472A patent/GB1369543A/en not_active Expired
- 1972-01-20 DE DE19722202728 patent/DE2202728A1/de active Pending
- 1972-01-21 FR FR7202069A patent/FR2122587B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH579036A5 (cg-RX-API-DMAC7.html) | 1976-08-31 |
| DE2202728A1 (de) | 1972-08-03 |
| US3737455A (en) | 1973-06-05 |
| AU3779372A (en) | 1973-07-12 |
| AU470524B2 (en) | 1976-03-18 |
| FR2122587B1 (cg-RX-API-DMAC7.html) | 1976-04-16 |
| FR2122587A1 (cg-RX-API-DMAC7.html) | 1972-09-01 |
| NL7200062A (cg-RX-API-DMAC7.html) | 1972-07-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |