GB1366391A - Benzodiazepine derivates processes for producing them and composi tions containing them - Google Patents

Benzodiazepine derivates processes for producing them and composi tions containing them

Info

Publication number
GB1366391A
GB1366391A GB4825971A GB4825971A GB1366391A GB 1366391 A GB1366391 A GB 1366391A GB 4825971 A GB4825971 A GB 4825971A GB 4825971 A GB4825971 A GB 4825971A GB 1366391 A GB1366391 A GB 1366391A
Authority
GB
United Kingdom
Prior art keywords
dec
alkyl
aralkyl
nov
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4825971A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9220170A external-priority patent/JPS4843916B1/ja
Priority claimed from JP10133270A external-priority patent/JPS4948555B1/ja
Priority claimed from JP10295170A external-priority patent/JPS49189B1/ja
Priority claimed from JP10510570A external-priority patent/JPS494467B1/ja
Priority claimed from JP10510370A external-priority patent/JPS4948556B1/ja
Priority claimed from JP10510670A external-priority patent/JPS49190B1/ja
Priority claimed from JP10996670A external-priority patent/JPS4914755B1/ja
Priority claimed from JP11446270A external-priority patent/JPS4839954B1/ja
Priority claimed from JP11599770A external-priority patent/JPS494468B1/ja
Priority claimed from JP12900870A external-priority patent/JPS502517B1/ja
Priority claimed from JP13038070A external-priority patent/JPS4843515B1/ja
Priority claimed from JP12996470A external-priority patent/JPS4835277B1/ja
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of GB1366391A publication Critical patent/GB1366391A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/36Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB4825971A 1970-10-19 1971-10-18 Benzodiazepine derivates processes for producing them and composi tions containing them Expired GB1366391A (en)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
JP9220170A JPS4843916B1 (enrdf_load_stackoverflow) 1970-10-19 1970-10-19
JP10133270A JPS4948555B1 (enrdf_load_stackoverflow) 1970-11-16 1970-11-16
JP10295170A JPS49189B1 (enrdf_load_stackoverflow) 1970-11-21 1970-11-21
JP10510370A JPS4948556B1 (enrdf_load_stackoverflow) 1970-11-28 1970-11-28
JP10510570A JPS494467B1 (enrdf_load_stackoverflow) 1970-11-28 1970-11-28
JP10510670A JPS49190B1 (enrdf_load_stackoverflow) 1970-11-28 1970-11-28
JP10996670A JPS4914755B1 (enrdf_load_stackoverflow) 1970-12-08 1970-12-08
JP10937070 1970-12-09
JP11446270A JPS4839954B1 (enrdf_load_stackoverflow) 1970-12-11 1970-12-11
JP11599770A JPS494468B1 (enrdf_load_stackoverflow) 1970-12-21 1970-12-21
JP12900870A JPS502517B1 (enrdf_load_stackoverflow) 1970-12-25 1970-12-25
JP13038070A JPS4843515B1 (enrdf_load_stackoverflow) 1970-12-26 1970-12-26
JP12996470A JPS4835277B1 (enrdf_load_stackoverflow) 1970-12-28 1970-12-28
FR7136763A FR2111689B1 (enrdf_load_stackoverflow) 1970-10-19 1971-10-13

Publications (1)

Publication Number Publication Date
GB1366391A true GB1366391A (en) 1974-09-11

Family

ID=27584710

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4825971A Expired GB1366391A (en) 1970-10-19 1971-10-18 Benzodiazepine derivates processes for producing them and composi tions containing them

Country Status (6)

Country Link
AT (5) AT314553B (enrdf_load_stackoverflow)
AU (1) AU442882B2 (enrdf_load_stackoverflow)
CH (7) CH585736A5 (enrdf_load_stackoverflow)
FR (1) FR2111689B1 (enrdf_load_stackoverflow)
GB (1) GB1366391A (enrdf_load_stackoverflow)
SE (1) SE387116B (enrdf_load_stackoverflow)

Also Published As

Publication number Publication date
CH584207A5 (enrdf_load_stackoverflow) 1977-01-31
SE387116B (sv) 1976-08-30
FR2111689A1 (enrdf_load_stackoverflow) 1972-06-09
CH585734A5 (enrdf_load_stackoverflow) 1977-03-15
AU3475571A (en) 1973-05-03
AT314551B (de) 1974-04-10
CH585736A5 (enrdf_load_stackoverflow) 1977-03-15
AT314552B (de) 1974-04-10
CH585735A5 (enrdf_load_stackoverflow) 1977-03-15
AU442882B2 (en) 1973-12-06
AT314550B (de) 1974-04-10
CH593949A5 (enrdf_load_stackoverflow) 1977-12-30
AT316564B (de) 1974-07-25
CH595353A5 (enrdf_load_stackoverflow) 1978-02-15
FR2111689B1 (enrdf_load_stackoverflow) 1975-08-01
AT314553B (de) 1974-04-10
CH585737A5 (enrdf_load_stackoverflow) 1977-03-15

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee