GB1358413A - Sydnone imine derivatives and processes for preparing them - Google Patents
Sydnone imine derivatives and processes for preparing themInfo
- Publication number
- GB1358413A GB1358413A GB4003771A GB4003771A GB1358413A GB 1358413 A GB1358413 A GB 1358413A GB 4003771 A GB4003771 A GB 4003771A GB 4003771 A GB4003771 A GB 4003771A GB 1358413 A GB1358413 A GB 1358413A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbon atoms
- radical
- alkyl
- formula
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Sydnone imine Chemical class 0.000 title abstract 19
- 125000004432 carbon atom Chemical group C* 0.000 abstract 12
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000005843 halogen group Chemical group 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003254 radicals Chemical class 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000005018 aryl alkenyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- KHUXNRRPPZOJPT-UHFFFAOYSA-N phenoxy radical Chemical compound O=C1C=C[CH]C=C1 KHUXNRRPPZOJPT-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE788052D BE788052A (fr) | 1971-08-26 | Nouveaux derives de la sydnone imine | |
| GB4003771A GB1358413A (en) | 1971-08-26 | 1971-08-26 | Sydnone imine derivatives and processes for preparing them |
| FR7225188A FR2150306B1 (https=) | 1971-08-26 | 1972-07-12 | |
| US277213A US3898230A (en) | 1971-08-26 | 1972-08-02 | Sydnone imine compounds |
| AU45292/72A AU464368B2 (en) | 1971-08-26 | 1972-08-04 | New sydnone imine derivatives and processes for preparing them |
| CA149,785*7A CA962271A (en) | 1971-08-26 | 1972-08-15 | Procede de preparation des nouveaux derives de la sydnone imine |
| DE2241991A DE2241991C3 (de) | 1971-08-26 | 1972-08-24 | Sydnonimin-Derivate, Verfahren zu deren Herstellung und diese Verbindungen als einzigen Wirkstoff enthaltende Arzneimitte !zusammensetzungen |
| JP47084933A JPS5133913B2 (https=) | 1971-08-26 | 1972-08-24 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4003771A GB1358413A (en) | 1971-08-26 | 1971-08-26 | Sydnone imine derivatives and processes for preparing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1358413A true GB1358413A (en) | 1974-07-03 |
Family
ID=10412852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4003771A Expired GB1358413A (en) | 1971-08-26 | 1971-08-26 | Sydnone imine derivatives and processes for preparing them |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3898230A (https=) |
| JP (1) | JPS5133913B2 (https=) |
| AU (1) | AU464368B2 (https=) |
| BE (1) | BE788052A (https=) |
| CA (1) | CA962271A (https=) |
| DE (1) | DE2241991C3 (https=) |
| FR (1) | FR2150306B1 (https=) |
| GB (1) | GB1358413A (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0076952A1 (en) * | 1981-10-06 | 1983-04-20 | Hiroyoshi Hidaka | N-acyl-3-(4-(benzoylalkyl)piperazin-1-yl)-sydnonimine compound, process for production thereof, and use thereof |
| US4421754A (en) * | 1981-08-24 | 1983-12-20 | Hiroyoshi Hidaka | Syndonimine derivatives, process for production thereof, and use thereof |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4368200A (en) * | 1978-06-23 | 1983-01-11 | Janssen Pharmaceutica N.V. | Heterocyclic derivatives of (4-phenyl-piperazine-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)-methyl-1H-imidazoles and 1H-1,2,4-triazoles |
| DE2930736A1 (de) * | 1979-07-28 | 1981-02-12 | Cassella Ag | Pharmakologisch wirksame, substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
| DE3107933A1 (de) * | 1981-03-02 | 1982-09-16 | Cassella Ag, 6000 Frankfurt | Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung |
| WO1997017334A1 (en) * | 1995-11-06 | 1997-05-15 | Chugai Seiyaku Kabushiki Kaisha | Sydnone imine derivatives |
| AR104882A1 (es) * | 2015-06-05 | 2017-08-23 | Orion Corp | DERIVADOS DE 2-(1-HETEROARILPIPERAZIN-4-IL)METIL-1,4-BENZODIOXANO COMO ANTAGONISTAS DE a2C |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1496056A (fr) * | 1964-06-08 | 1967-09-29 | Takeda Chemical Industries Ltd | Nouveaux composés chimiques du type sydnonimine |
-
0
- BE BE788052D patent/BE788052A/xx unknown
-
1971
- 1971-08-26 GB GB4003771A patent/GB1358413A/en not_active Expired
-
1972
- 1972-07-12 FR FR7225188A patent/FR2150306B1/fr not_active Expired
- 1972-08-02 US US277213A patent/US3898230A/en not_active Expired - Lifetime
- 1972-08-04 AU AU45292/72A patent/AU464368B2/en not_active Expired
- 1972-08-15 CA CA149,785*7A patent/CA962271A/en not_active Expired
- 1972-08-24 DE DE2241991A patent/DE2241991C3/de not_active Expired
- 1972-08-24 JP JP47084933A patent/JPS5133913B2/ja not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4421754A (en) * | 1981-08-24 | 1983-12-20 | Hiroyoshi Hidaka | Syndonimine derivatives, process for production thereof, and use thereof |
| EP0076952A1 (en) * | 1981-10-06 | 1983-04-20 | Hiroyoshi Hidaka | N-acyl-3-(4-(benzoylalkyl)piperazin-1-yl)-sydnonimine compound, process for production thereof, and use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| US3898230A (en) | 1975-08-05 |
| CA962271A (en) | 1975-02-04 |
| JPS5133913B2 (https=) | 1976-09-22 |
| AU4529272A (en) | 1974-02-07 |
| FR2150306B1 (https=) | 1975-10-17 |
| DE2241991A1 (de) | 1973-03-15 |
| DE2241991B2 (de) | 1974-11-07 |
| AU464368B2 (en) | 1975-08-21 |
| BE788052A (fr) | 1973-02-26 |
| JPS4832890A (https=) | 1973-05-02 |
| DE2241991C3 (de) | 1975-06-26 |
| FR2150306A1 (https=) | 1973-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |