GB1356789A - Derivatives of theophylline - Google Patents
Derivatives of theophyllineInfo
- Publication number
- GB1356789A GB1356789A GB3802570A GB3802570A GB1356789A GB 1356789 A GB1356789 A GB 1356789A GB 3802570 A GB3802570 A GB 3802570A GB 3802570 A GB3802570 A GB 3802570A GB 1356789 A GB1356789 A GB 1356789A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- theophylline
- pyridine
- reacting
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical class O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 title abstract 5
- -1 pyridine-carbonyl Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 239000012442 inert solvent Substances 0.000 abstract 2
- 229910052740 iodine Inorganic materials 0.000 abstract 2
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 2
- 229960000278 theophylline Drugs 0.000 abstract 2
- 101100294106 Caenorhabditis elegans nhr-3 gene Proteins 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000002269 analeptic agent Substances 0.000 abstract 1
- 230000003555 analeptic effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000916 dilatatory effect Effects 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000003212 lipotrophic effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 230000002107 myocardial effect Effects 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- SIOXPEMLGUPBBT-UHFFFAOYSA-N picolinic acid Chemical compound OC(=O)C1=CC=CC=N1 SIOXPEMLGUPBBT-UHFFFAOYSA-N 0.000 abstract 1
- 230000002040 relaxant effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3802570A GB1356789A (en) | 1970-08-06 | 1970-08-06 | Derivatives of theophylline |
| FR7128797A FR2102082B2 (enrdf_load_stackoverflow) | 1970-08-06 | 1971-08-05 | |
| BE771009A BE771009R (fr) | 1970-08-06 | 1971-08-05 | Derives de la |
| ES393934A ES393934A2 (es) | 1970-08-06 | 1971-08-05 | Procedimiento para la preparacion de derivados de teofili- na. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3802570A GB1356789A (en) | 1970-08-06 | 1970-08-06 | Derivatives of theophylline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1356789A true GB1356789A (en) | 1974-06-12 |
Family
ID=10400674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3802570A Expired GB1356789A (en) | 1970-08-06 | 1970-08-06 | Derivatives of theophylline |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE771009R (enrdf_load_stackoverflow) |
| ES (1) | ES393934A2 (enrdf_load_stackoverflow) |
| FR (1) | FR2102082B2 (enrdf_load_stackoverflow) |
| GB (1) | GB1356789A (enrdf_load_stackoverflow) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5641783A (en) * | 1993-11-12 | 1997-06-24 | Cell Therapeutics, Inc. | Substituted amino alcohol compounds |
| US5801181A (en) * | 1993-03-31 | 1998-09-01 | Cell Therapeutics, Inc. | Amino alcohol substituted cyclic compounds |
| US11426412B2 (en) | 2017-10-18 | 2022-08-30 | Jubilant Epipad LLC | Imidazo-pyridine compounds as PAD inhibitors |
| US11459338B2 (en) | 2017-11-24 | 2022-10-04 | Jubilant Episcribe Llc | Heterocyclic compounds as PRMT5 inhibitors |
| US11529341B2 (en) | 2018-03-13 | 2022-12-20 | Jubilant Prodel LLC | Bicyclic compounds as inhibitors of PD1/PD-L1 interaction/activation |
| US11629135B2 (en) | 2017-11-06 | 2023-04-18 | Jubilant Prodell Llc | Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation |
| US11833156B2 (en) | 2017-09-22 | 2023-12-05 | Jubilant Epipad LLC | Heterocyclic compounds as pad inhibitors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1230663A (enrdf_load_stackoverflow) * | 1968-12-10 | 1971-05-05 |
-
1970
- 1970-08-06 GB GB3802570A patent/GB1356789A/en not_active Expired
-
1971
- 1971-08-05 FR FR7128797A patent/FR2102082B2/fr not_active Expired
- 1971-08-05 BE BE771009A patent/BE771009R/xx active
- 1971-08-05 ES ES393934A patent/ES393934A2/es not_active Expired
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750575A (en) * | 1993-03-31 | 1998-05-12 | Cell Therapeutics, Inc. | Substituted amino alcohol compounds |
| US5777117A (en) * | 1993-03-31 | 1998-07-07 | Cell Therapeutics, Inc. | Method for preparing substituted amino alcohol compounds |
| US5801181A (en) * | 1993-03-31 | 1998-09-01 | Cell Therapeutics, Inc. | Amino alcohol substituted cyclic compounds |
| US5824677A (en) * | 1993-03-31 | 1998-10-20 | Cell Therapeutics, Inc. | Substituted amino alcohol compounds |
| US5837703A (en) * | 1993-03-31 | 1998-11-17 | Cell Therapeutics, Inc. | Amino-alcohol substituted cyclic compounds |
| US5641783A (en) * | 1993-11-12 | 1997-06-24 | Cell Therapeutics, Inc. | Substituted amino alcohol compounds |
| US11833156B2 (en) | 2017-09-22 | 2023-12-05 | Jubilant Epipad LLC | Heterocyclic compounds as pad inhibitors |
| US12357639B2 (en) | 2017-09-22 | 2025-07-15 | Jubilant Epipad LLC | Heterocyclic compounds as pad inhibitors |
| US11426412B2 (en) | 2017-10-18 | 2022-08-30 | Jubilant Epipad LLC | Imidazo-pyridine compounds as PAD inhibitors |
| US11629135B2 (en) | 2017-11-06 | 2023-04-18 | Jubilant Prodell Llc | Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation |
| US11459338B2 (en) | 2017-11-24 | 2022-10-04 | Jubilant Episcribe Llc | Heterocyclic compounds as PRMT5 inhibitors |
| US11529341B2 (en) | 2018-03-13 | 2022-12-20 | Jubilant Prodel LLC | Bicyclic compounds as inhibitors of PD1/PD-L1 interaction/activation |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2102082B2 (enrdf_load_stackoverflow) | 1974-10-18 |
| ES393934A2 (es) | 1974-02-16 |
| FR2102082A2 (enrdf_load_stackoverflow) | 1972-04-07 |
| BE771009R (fr) | 1971-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |