GB1355163A - Method for preparing heliomycin - Google Patents

Method for preparing heliomycin

Info

Publication number
GB1355163A
GB1355163A GB1195972A GB1195972A GB1355163A GB 1355163 A GB1355163 A GB 1355163A GB 1195972 A GB1195972 A GB 1195972A GB 1195972 A GB1195972 A GB 1195972A GB 1355163 A GB1355163 A GB 1355163A
Authority
GB
United Kingdom
Prior art keywords
heliomycin
mycelium
march
precipitate
extract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1195972A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VNII IZYSKANIJU NOVYKH ANTIBIO
Original Assignee
VNII IZYSKANIJU NOVYKH ANTIBIO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VNII IZYSKANIJU NOVYKH ANTIBIO filed Critical VNII IZYSKANIJU NOVYKH ANTIBIO
Publication of GB1355163A publication Critical patent/GB1355163A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

1355163 Producing heliomycin VSESOJUZNY NAUCHNO-ISSLEDOVATELSKY INSTITUT PO IZYSKANIJU NOVYKH ANTIBIOTIKOV AKADEMII MEDITSINSKIKH NAUK SSSR 15 March 1972 - [17 March 1971] 11959/72 Heading C2A The antibiotic heliomycin is prepared by cultivating Actinomyces variabilis var. roseolus (Strain No. 6383) under aerobic conditions on a nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts, separating the mycelium and extracting heliomycin therefrom. The medium preferably contains soya bean flour and starch as nutrients, the cultivation being carried out under submerged aerobic conditions at 28‹ C. The mycelium is filtered off and the moist filter cake is extracted four times with acetone. The first extract is discarded, the fourth extract is re-cycled for the second extraction of another batch, and the second and third extracts are combined and mixed with twice their volume of water to precipitate heliomycin. The precipitate is washed with water and then with petroleum ether and dried to give a preparation containing 80-85% by weight of heliomycin.
GB1195972A 1971-03-17 1972-03-15 Method for preparing heliomycin Expired GB1355163A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU1626871A SU350364A1 (en) 1971-03-17 1971-03-17 GELIOMYCIN PRODUCER

Publications (1)

Publication Number Publication Date
GB1355163A true GB1355163A (en) 1974-06-05

Family

ID=20467153

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1195972A Expired GB1355163A (en) 1971-03-17 1972-03-15 Method for preparing heliomycin

Country Status (5)

Country Link
CH (1) CH568387A5 (en)
DE (1) DE2212854C3 (en)
FR (1) FR2130267B1 (en)
GB (1) GB1355163A (en)
SU (1) SU350364A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6916782B1 (en) 1998-04-15 2005-07-12 Aventis Cropscience S.A. Gene coding for heliomicine and use thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6916782B1 (en) 1998-04-15 2005-07-12 Aventis Cropscience S.A. Gene coding for heliomicine and use thereof

Also Published As

Publication number Publication date
DE2212854C3 (en) 1974-11-28
DE2212854B2 (en) 1974-04-25
FR2130267B1 (en) 1975-04-25
FR2130267A1 (en) 1972-11-03
CH568387A5 (en) 1975-10-31
SU350364A1 (en) 1973-10-19
DE2212854A1 (en) 1972-11-02

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee