GB1353072A - Benzimidazole derivative and therapeutic compositions containing the same - Google Patents

Benzimidazole derivative and therapeutic compositions containing the same

Info

Publication number
GB1353072A
GB1353072A GB1628071A GB1628071A GB1353072A GB 1353072 A GB1353072 A GB 1353072A GB 1628071 A GB1628071 A GB 1628071A GB 1628071 A GB1628071 A GB 1628071A GB 1353072 A GB1353072 A GB 1353072A
Authority
GB
United Kingdom
Prior art keywords
hydrochloride
hypertensive
contain
sulphate
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1628071A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB1353072A publication Critical patent/GB1353072A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/38—Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1353072 Hypertensive medicines UPJOHN CO 21 May 1971 [9 June 1970] 16280/71 Heading A5B [Also in Division C2] Pharmaceutical compositions, suitable for oral or parenteral administration, contain the novel compound N-(5,6-dimethyl-2-benzimdazolyl) - acetamide or its pharmacologically acceptable acid addition salts and pharmaceutically acceptable carriers. The compound possesses hypertensive activity. The compositions may contain other hypertensive agents, such as hydralazine hydrochloride, hexamethonium bromide, mecamylamine hydrochloride, phenoxybenzamine hydrochloride, guanethidine sulphate and methyldopa, or diuretic agents such as ethoxyzolamide, hydrochlorothiazide, trichloromethazide, reserpine and acetazolamide, or sedatives and tranquilizers such as phenobarbital, pentobarbital, chloral hydrate, chorpromazine, thioridozine, diazepam butabarbital, amobarbital, chlordiazepoxide, haloperidol, meprobamate and ectylurea, or antidepressants such as amitriptyline hydrochloride, methylphenidate hydrochloride, d-amphetamine sulphate and methomphetamine hydrochloride, or analgesics such as aspirin and acetaminophen.
GB1628071A 1970-06-09 1971-05-21 Benzimidazole derivative and therapeutic compositions containing the same Expired GB1353072A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4490370A 1970-06-09 1970-06-09

Publications (1)

Publication Number Publication Date
GB1353072A true GB1353072A (en) 1974-05-15

Family

ID=21934952

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1628071A Expired GB1353072A (en) 1970-06-09 1971-05-21 Benzimidazole derivative and therapeutic compositions containing the same

Country Status (10)

Country Link
AU (1) AU2982071A (en)
BE (1) BE768300A (en)
CA (1) CA952911A (en)
DE (1) DE2127960A1 (en)
FR (1) FR2100740B1 (en)
GB (1) GB1353072A (en)
IL (1) IL36892A (en)
NL (1) NL7107851A (en)
PH (1) PH9420A (en)
ZA (1) ZA713189B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US340A (en) * 1837-07-31 Cooking-stove
DE71C (en) * 1877-07-01 W. SENNECKE, Berlin W., Charlottenstrafse 27 Device to save on mashing room in fermentation vats and at the same time to regulate the fermentation process

Also Published As

Publication number Publication date
BE768300A (en) 1971-12-09
PH9420A (en) 1975-11-14
CA952911A (en) 1974-08-13
IL36892A (en) 1974-05-16
FR2100740B1 (en) 1975-04-18
DE2127960A1 (en) 1971-12-16
ZA713189B (en) 1972-01-26
NL7107851A (en) 1971-12-13
IL36892A0 (en) 1971-07-28
FR2100740A1 (en) 1972-03-24
AU2982071A (en) 1972-12-14

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees