GB1351558A - Dibenzothiazocine oxides - Google Patents
Dibenzothiazocine oxidesInfo
- Publication number
- GB1351558A GB1351558A GB4644772A GB4644772A GB1351558A GB 1351558 A GB1351558 A GB 1351558A GB 4644772 A GB4644772 A GB 4644772A GB 4644772 A GB4644772 A GB 4644772A GB 1351558 A GB1351558 A GB 1351558A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- formula
- alkyl group
- dibenzothiazocine
- oct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/18—Eight-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
1351558 Dibenzothiazocine oxides EISAI CO Ltd 9 Oct 1972 [8 Oct 1971] 46447/72 Heading C2C Compounds having the formula wherein n = 1 or 2 and R is a C 1 to C 4 alkyl, C 1 to C 4 alkenyl or benzyl group or a C 1 to C 4 alkyl group substituted with halogen, hydroxyl or (wherein R<SP>1</SP> is a hydrogen atom or a C 1 to C 4 alkyl group and R<SP>2</SP> is a C 1 to C 4 alkyl group; or R<SP>1</SP> and R<SP>2</SP> together with the nitrogen atom to which they are attached, constitute a heterocyclic group which may optionally also contain other hetero atoms): and pharmaceutioally acceptable salts thereof are claimed per se. These compounds may be prepared by reacting a bis-(2-halomethylphenyl) sulphide S-oxide of formula (wherein n = 1 or 2 and X is a halogen atom) with a primary amine of formula H 2 N-R (wherein R has the above meaning) and if desired salifying the product of the reaction. The reaction may be carried out in the presence of an acid bonding agent. The compounds may be used in pharmaceutical compositions together with a pharmaceutical carrier or diluent.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7871571A JPS5133117B2 (en) | 1971-10-08 | 1971-10-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1351558A true GB1351558A (en) | 1974-05-01 |
Family
ID=13669552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4644772A Expired GB1351558A (en) | 1971-10-08 | 1972-10-09 | Dibenzothiazocine oxides |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS5133117B2 (en) |
| DE (1) | DE2246707A1 (en) |
| FR (1) | FR2155949B1 (en) |
| GB (1) | GB1351558A (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3803143A (en) * | 1969-09-08 | 1974-04-09 | Eisai Co Ltd | 6-amino alkylene 6,7-dihydro-5h-dibenzo (b,g),(1,5)thiazocines |
-
1971
- 1971-10-08 JP JP7871571A patent/JPS5133117B2/ja not_active Expired
-
1972
- 1972-09-22 DE DE19722246707 patent/DE2246707A1/en active Pending
- 1972-09-29 FR FR7234645A patent/FR2155949B1/fr not_active Expired
- 1972-10-09 GB GB4644772A patent/GB1351558A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2155949B1 (en) | 1975-10-17 |
| JPS5133117B2 (en) | 1976-09-17 |
| DE2246707A1 (en) | 1973-04-12 |
| FR2155949A1 (en) | 1973-05-25 |
| JPS4840793A (en) | 1973-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |