GB1350413A - Benzotriazepines processes for their preparation and compositions incorporating them - Google Patents
Benzotriazepines processes for their preparation and compositions incorporating themInfo
- Publication number
- GB1350413A GB1350413A GB3373571A GB3373571A GB1350413A GB 1350413 A GB1350413 A GB 1350413A GB 3373571 A GB3373571 A GB 3373571A GB 3373571 A GB3373571 A GB 3373571A GB 1350413 A GB1350413 A GB 1350413A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- oco
- alkyl
- formula
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- QVWKODLMAFCGLB-UHFFFAOYSA-N 1H-1,2,3-benzotriazepine Chemical class N1N=NC=CC2=CC=CC=C12 QVWKODLMAFCGLB-UHFFFAOYSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 15
- 125000000217 alkyl group Chemical group 0.000 abstract 8
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
- -1 CF 3 Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 229910003827 NRaRb Inorganic materials 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 229910052717 sulfur Inorganic materials 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- MLIREBYILWEBDM-UHFFFAOYSA-N cyanoacetic acid Chemical compound OC(=O)CC#N MLIREBYILWEBDM-UHFFFAOYSA-N 0.000 abstract 2
- 125000002349 hydroxyamino group Chemical group [H]ON([H])[*] 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 abstract 1
- 125000001766 1,2,4-oxadiazol-3-yl group Chemical group [H]C1=NC(*)=NO1 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000002269 analeptic agent Substances 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2757970 | 1970-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1350413A true GB1350413A (en) | 1974-04-18 |
Family
ID=11221924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3373571A Expired GB1350413A (en) | 1970-07-17 | 1971-07-19 | Benzotriazepines processes for their preparation and compositions incorporating them |
Country Status (14)
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1056710B (it) * | 1967-03-07 | 1982-02-20 | Lab Farmaceutici Maestretti So | 4 cheto ih 4,5 diidro 1,2,5 benzo triazepine utili come fafarmaci e processo per la loro preparazione |
| FR2073289B1 (enrdf_load_stackoverflow) * | 1969-12-30 | 1973-01-12 | Roussel Uclaf |
-
1971
- 1971-06-29 FR FR7123685A patent/FR2100922B1/fr not_active Expired
- 1971-07-09 CH CH1012971A patent/CH543524A/fr not_active IP Right Cessation
- 1971-07-09 CH CH1464872A patent/CH543525A/fr not_active IP Right Cessation
- 1971-07-12 IL IL37298A patent/IL37298A0/xx unknown
- 1971-07-15 BE BE770031A patent/BE770031A/xx unknown
- 1971-07-15 HU HURO619A patent/HU163435B/hu unknown
- 1971-07-16 ZA ZA714743A patent/ZA714743B/xx unknown
- 1971-07-16 NL NL7109885A patent/NL7109885A/xx unknown
- 1971-07-16 AU AU31325/71A patent/AU3132571A/en not_active Expired
- 1971-07-16 AT AT624671A patent/AT311975B/de not_active IP Right Cessation
- 1971-07-16 CA CA118,475*7A patent/CA945160A/en not_active Expired
- 1971-07-16 DE DE19712135765 patent/DE2135765A1/de active Pending
- 1971-07-16 AR AR236822A patent/AR192716A1/es active
- 1971-07-16 ES ES393364A patent/ES393364A1/es not_active Expired
- 1971-07-19 GB GB3373571A patent/GB1350413A/en not_active Expired
-
1972
- 1972-02-12 ES ES399727A patent/ES399727A1/es not_active Expired
- 1972-02-12 ES ES399728A patent/ES399728A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH543525A (fr) | 1973-12-14 |
| FR2100922B1 (enrdf_load_stackoverflow) | 1974-11-15 |
| DE2135765A1 (de) | 1972-01-20 |
| ES399727A1 (es) | 1974-11-16 |
| HU163435B (enrdf_load_stackoverflow) | 1973-08-28 |
| NL7109885A (enrdf_load_stackoverflow) | 1972-01-19 |
| ES393364A1 (es) | 1973-08-16 |
| AR192716A1 (es) | 1973-03-14 |
| FR2100922A1 (enrdf_load_stackoverflow) | 1972-03-24 |
| ZA714743B (en) | 1972-11-29 |
| CA945160A (en) | 1974-04-09 |
| AT311975B (de) | 1973-12-10 |
| CH543524A (fr) | 1973-10-31 |
| IL37298A0 (en) | 1971-10-20 |
| BE770031A (fr) | 1972-01-17 |
| ES399728A1 (es) | 1974-11-16 |
| AU3132571A (en) | 1973-01-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |