GB1346486A - Method and apparatus for densitometric analysis - Google Patents

Method and apparatus for densitometric analysis

Info

Publication number
GB1346486A
GB1346486A GB2649971*A GB2649971A GB1346486A GB 1346486 A GB1346486 A GB 1346486A GB 2649971 A GB2649971 A GB 2649971A GB 1346486 A GB1346486 A GB 1346486A
Authority
GB
United Kingdom
Prior art keywords
sample
values
scanning
recording
value
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2649971*A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clifford Instruments Inc
Original Assignee
Clifford Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clifford Instruments Inc filed Critical Clifford Instruments Inc
Publication of GB1346486A publication Critical patent/GB1346486A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G01N21/5907—Densitometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • G01N30/95—Detectors specially adapted therefor; Signal analysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

1346486 Photo-electric analysis CLIFFORD INSTRUMENTS Inc 19 April 1971 [9 April 1970 18 Jan 1971] 26499/71 Heading G1A A recording densitometer comprises means mounted for scanning a sample responsive to energy from the sample, means for traversing a recording chart synchronously with the sample scanning and for producing an analogue record trace, means for integrating the area under the trace, during the whole traverse means for marking manually areas of interest on the recording means for rescanning the sample and for dividing the signals obtained by the integrated value of the previous whole trace, means for responding to the detection of the marks to integrate over desired areas the said divided value, and means for printing digitally on the chart in the predetermined areas the values of the integrated divided values, "area per cent" values and such values multiplied by an inset "quantity of material" value. The size and route of traverse may be adjustable and values may be stored and fed into the circuitry for calibration purposes. The process may be automatically controlled and the energy may be light including U. V. or infrared, transmitted through, or reflected by, the sample, or, may be radiation from the sample due to fluorescence or tagging. Biological applications e.g. zone electro-phoresis including blood analysis are referred to The sample may be an electro-phoresis strip secured magnetically to the apparatus. Integration is achieved by producing pulses having a recurrence frequency proportional to the detector voltage and storing them, e.g. in a counter. The signal may be mathematically treated to indicate directly the value being measured, logarithmic conversion and inversion being exemplified. Clock pulses are used both for control and for driving, the traversing motor, separate motors being provided for sample scanning and recording, the limits of scanning being determined by up-down counters and limit switches.
GB2649971*A 1970-04-09 1971-04-19 Method and apparatus for densitometric analysis Expired GB1346486A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2706770A 1970-04-09 1970-04-09
US10714071A 1971-01-18 1971-01-18

Publications (1)

Publication Number Publication Date
GB1346486A true GB1346486A (en) 1974-02-13

Family

ID=26701999

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2649971*A Expired GB1346486A (en) 1970-04-09 1971-04-19 Method and apparatus for densitometric analysis

Country Status (5)

Country Link
US (1) US3706877A (en)
CA (1) CA927623A (en)
DE (1) DE2117385A1 (en)
FR (1) FR2089411A5 (en)
GB (1) GB1346486A (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3784789A (en) * 1972-06-22 1974-01-08 Transidyne Gen Corp Fraction computer for multi-component trace
US3828173A (en) * 1972-08-01 1974-08-06 Dickey John Corp Grain analysis computer circuit
US3767899A (en) * 1972-08-07 1973-10-23 Beckman Instruments Inc Digital integrator for evaluating operator selected portions of analog chart traces
GB1471143A (en) * 1973-04-09 1977-04-21 Joyce Loebl Ltd Automatic graphing apparatus
US3916176A (en) * 1973-08-30 1975-10-28 Imant Karlovich Alien Method for classifying supposedly cancerous cytologic preparations and apparatus for identifying supposedly cancerous cytologic preparations effecting this method
US3842422A (en) * 1973-10-12 1974-10-15 Transidyne Gen Corp Method and apparatus for recording signals
US3919530A (en) * 1974-04-10 1975-11-11 George Chiwo Cheng Color information leukocytes analysis system
US4005434A (en) * 1975-03-24 1977-01-25 Helena Laboratories Corporation Method and apparatus for graphic densitometer display
US4116565A (en) * 1977-05-24 1978-09-26 Corning Glass Works Electrophoretic analyzer with automatic reference circuit
US4118781A (en) * 1977-05-24 1978-10-03 Corning Glass Works Valley sensor for an electrophoretic analyzer
US4097735A (en) * 1977-05-24 1978-06-27 Corning Glass Works Testing the operation of a recording fluorometer/densitometer
US4130824A (en) * 1977-05-24 1978-12-19 Corning Glass Works Recording analyzer for electrophoretic samples
IT1086463B (en) * 1977-09-06 1985-05-28 Fisauli Francesco DENSITOMETER FOR THE QUANTITATIVE DETERMINATION OF PROTEIN FRACTIONS SEPARATED ELECTROPHORETICALLY, ESPECIALLY FOR CLINICAL DIAGNOSIS
US4242730A (en) * 1979-03-09 1980-12-30 Helena Laboratories Corporation Single scan microprocessor-controlled densitometer
JPS5942683Y2 (en) * 1979-06-08 1984-12-14 オリンパス光学工業株式会社 densitometer
US4352557A (en) * 1979-10-20 1982-10-05 Ernst Leitz Wetzlar Gmbh Determining a test value corresponding to blood subsidence
GB2068537B (en) * 1980-02-04 1984-11-14 Energy Conversion Devices Inc Examining biological materials
JPS5917142A (en) * 1982-07-20 1984-01-28 Olympus Optical Co Ltd Recording method of densitogram
US4720788A (en) * 1984-06-20 1988-01-19 Helena Laboratories Corporation Diagnostic densitometer
US4926356A (en) * 1988-02-29 1990-05-15 The Boeing Company Test apparatus for measuring heat release of certain materials
JP2738966B2 (en) * 1989-12-21 1998-04-08 オリンパス光学工業株式会社 Electrophoresis device
US6733645B1 (en) 2000-04-18 2004-05-11 Caliper Technologies Corp. Total analyte quantitation
US7546048B2 (en) * 2006-01-12 2009-06-09 Sun Chemical Corporation Method for determining ink usage efficiency in commercial printing processes using pigments and quantitative tests

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2732504A (en) * 1948-09-28 1956-01-24 steele
US2834247A (en) * 1955-01-26 1958-05-13 Beckman Instruments Inc Optical density analyzing apparatus
US3187168A (en) * 1960-02-23 1965-06-01 Beckman Instruments Inc Integrator
US3098689A (en) * 1960-12-13 1963-07-23 Union Carbide Corp Integral recording
US3259733A (en) * 1961-02-24 1966-07-05 Chevron Res Automatic integrator for chromatograph records
US3185820A (en) * 1962-02-12 1965-05-25 Infotronics Corp Integrator and recorder apparatus
US3251055A (en) * 1963-08-26 1966-05-10 Gen Precision Inc Solid state analog to digital display scanner
US3335408A (en) * 1964-04-15 1967-08-08 Itek Corp Apparatus for data processing

Also Published As

Publication number Publication date
CA927623A (en) 1973-06-05
US3706877A (en) 1972-12-19
FR2089411A5 (en) 1972-01-07
DE2117385A1 (en) 1971-11-04

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee