GB1344792A - Production of a-l-aspartyl-l-phenyl-alanine alkyl esters - Google Patents

Production of a-l-aspartyl-l-phenyl-alanine alkyl esters

Info

Publication number
GB1344792A
GB1344792A GB3086772A GB3086772A GB1344792A GB 1344792 A GB1344792 A GB 1344792A GB 3086772 A GB3086772 A GB 3086772A GB 3086772 A GB3086772 A GB 3086772A GB 1344792 A GB1344792 A GB 1344792A
Authority
GB
United Kingdom
Prior art keywords
aspartyl
phenylalanine
alkyl esters
phenyl
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3086772A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of GB1344792A publication Critical patent/GB1344792A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Abstract

1344792 α - L - Aspartyl - L - phenylalanine alkyl esters AJINOMOTO CO Inc 30 June 1972 [9 July 1971] 30867/72 Addition to 1309605 Heading C2C An α- L - aspartyl - L - phenylalanine C 1-4 alkyl ester is prepared by reacting a strong acid salt of L-aspartic anhydride with a C 1-4 alkyl ester of phenylalanine in the presence of an inorganic acid having a dissociation constant determined at 25‹ C. or a first dissociation constant determined at 25‹ C. less than 3 x 10<SP>-2</SP> or in the presence of an oxide capable of forming said inorganic acid in the presence of water and separating the desired ester from the #-L- aspartyl-L-phenylalanine C 1-4 alhyl ester also produced.
GB3086772A 1971-07-09 1972-06-30 Production of a-l-aspartyl-l-phenyl-alanine alkyl esters Expired GB1344792A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5087771A JPS5140069B1 (en) 1971-07-09 1971-07-09

Publications (1)

Publication Number Publication Date
GB1344792A true GB1344792A (en) 1974-01-23

Family

ID=12870937

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3086772A Expired GB1344792A (en) 1971-07-09 1972-06-30 Production of a-l-aspartyl-l-phenyl-alanine alkyl esters

Country Status (7)

Country Link
JP (1) JPS5140069B1 (en)
CA (1) CA994328A (en)
CH (1) CH536818A (en)
DE (1) DE2233535C3 (en)
FR (1) FR2145979A6 (en)
GB (1) GB1344792A (en)
IE (1) IE36583B1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4941425B1 (en) * 1970-10-26 1974-11-08
CA1027112A (en) * 1973-03-05 1978-02-28 Willard M. Hoehn Process for isolation of dipeptide esters
DE2457874C2 (en) * 1974-12-06 1983-12-08 Ajinomoto Co., Inc., Tokyo Process for the preparation of α-L-aspartyl-L-phenylalanine methyl and ethyl esters
FR2295015A1 (en) * 1974-12-18 1976-07-16 Ajinomoto Kk Alpha-L-aspartyl-L-phenylalanine-lower alkyl esters prepn - from L-aspartic acid deriv and L-phenylalanine lower alkyl ester
IE810577L (en) * 1983-05-31 1982-09-16 Prendergast Angela Apparatus for fermentation

Also Published As

Publication number Publication date
DE2233535A1 (en) 1973-01-25
FR2145979A6 (en) 1973-02-23
DE2233535C3 (en) 1982-05-06
CA994328A (en) 1976-08-03
CH536818A (en) 1973-05-15
IE36583L (en) 1973-01-09
DE2233535B2 (en) 1981-07-23
IE36583B1 (en) 1976-12-08
JPS5140069B1 (en) 1976-11-01

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Legal Events

Date Code Title Description
PS Patent sealed