GB1343618A - Piperidine derivatives - Google Patents
Piperidine derivativesInfo
- Publication number
- GB1343618A GB1343618A GB2614771*A GB2614771A GB1343618A GB 1343618 A GB1343618 A GB 1343618A GB 2614771 A GB2614771 A GB 2614771A GB 1343618 A GB1343618 A GB 1343618A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenylpiperidine
- benzoyl
- alkyl
- methyl
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003053 piperidines Chemical class 0.000 title abstract 2
- -1 bromo- Chemical class 0.000 abstract 8
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- AIUGCCRGGIRXQC-UHFFFAOYSA-N (1-methyl-3-phenylpiperidin-4-yl)-phenylmethanone Chemical compound C1N(C)CCC(C(=O)C=2C=CC=CC=2)C1C1=CC=CC=C1 AIUGCCRGGIRXQC-UHFFFAOYSA-N 0.000 abstract 1
- PYNBGTIFODDTRW-UHFFFAOYSA-N (4-benzoyl-1-methyl-3-phenylpiperidin-4-yl) acetate Chemical compound CN1CCC(OC(C)=O)(C(C1)C1=CC=CC=C1)C(=O)C1=CC=CC=C1 PYNBGTIFODDTRW-UHFFFAOYSA-N 0.000 abstract 1
- OGWAWDBXBGRLEQ-UHFFFAOYSA-N (4-bromo-1-methyl-3-phenylpiperidin-4-yl)-phenylmethanone Chemical compound C(C1=CC=CC=C1)(=O)C1(C(CN(CC1)C)C1=CC=CC=C1)Br OGWAWDBXBGRLEQ-UHFFFAOYSA-N 0.000 abstract 1
- GADCSODZDASQJN-UHFFFAOYSA-N (4-hydroxy-1-methyl-3-phenylpiperidin-4-yl)-phenylmethanone Chemical compound C(C1=CC=CC=C1)(=O)C1(C(CN(CC1)C)C1=CC=CC=C1)O GADCSODZDASQJN-UHFFFAOYSA-N 0.000 abstract 1
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- LJAPMASBQRQOCI-UHFFFAOYSA-N ethyl 1-methyl-3-phenylpiperidine-4-carboxylate Chemical compound CCOC(=O)C1CCN(C)CC1C1=CC=CC=C1 LJAPMASBQRQOCI-UHFFFAOYSA-N 0.000 abstract 1
- VHHAMVPFHQZXNQ-UHFFFAOYSA-N ethyl 4-acetyloxy-4-benzoyl-3-phenylpiperidine-1-carboxylate Chemical compound CCOC(=O)N1CCC(OC(C)=O)(C(C1)C1=CC=CC=C1)C(=O)C1=CC=CC=C1 VHHAMVPFHQZXNQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 230000000055 hyoplipidemic effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
- C07D211/50—Aroyl radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/38—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH516770A CH528506A (de) | 1972-03-30 | 1972-03-30 | Verfahren zur Herstellung neuer Phenylpiperidinverbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1343618A true GB1343618A (en) | 1974-01-16 |
Family
ID=4289042
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2614771*A Expired GB1343618A (en) | 1972-03-30 | 1971-04-19 | Piperidine derivatives |
| GB3135973A Expired GB1343619A (en) | 1972-03-30 | 1971-04-19 | Benzoyl phenylpiperidine derivative |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3135973A Expired GB1343619A (en) | 1972-03-30 | 1971-04-19 | Benzoyl phenylpiperidine derivative |
Country Status (5)
| Country | Link |
|---|---|
| AT (1) | AT322554B (enExample) |
| CH (1) | CH528506A (enExample) |
| CS (1) | CS161902B2 (enExample) |
| GB (2) | GB1343618A (enExample) |
| ZA (1) | ZA712284B (enExample) |
-
1971
- 1971-04-06 CS CS2447A patent/CS161902B2/cs unknown
- 1971-04-07 AT AT296171A patent/AT322554B/de not_active IP Right Cessation
- 1971-04-08 ZA ZA712284A patent/ZA712284B/xx unknown
- 1971-04-19 GB GB2614771*A patent/GB1343618A/en not_active Expired
- 1971-04-19 GB GB3135973A patent/GB1343619A/en not_active Expired
-
1972
- 1972-03-30 CH CH516770A patent/CH528506A/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB1343619A (en) | 1974-01-16 |
| CH528506A (de) | 1972-09-30 |
| ZA712284B (en) | 1972-11-29 |
| AT322554B (de) | 1975-05-26 |
| CS161902B2 (enExample) | 1975-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |