GB1343247A - Diagnostic agent for the detection of urobilinogen bodies in body fluids - Google Patents
Diagnostic agent for the detection of urobilinogen bodies in body fluidsInfo
- Publication number
- GB1343247A GB1343247A GB2781372A GB2781372A GB1343247A GB 1343247 A GB1343247 A GB 1343247A GB 2781372 A GB2781372 A GB 2781372A GB 2781372 A GB2781372 A GB 2781372A GB 1343247 A GB1343247 A GB 1343247A
- Authority
- GB
- United Kingdom
- Prior art keywords
- nrobilinogen
- diagnostic agent
- diazonium salt
- body fluids
- detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/903—Diazo reactions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
- Y10T436/146666—Bile pigment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
1343247 Determination of nrobilinogen BOEHRINGER MANNHEIM GmbH 14 June 1972 [19 June 1971] 27813/72 Heading BIX A diagnostic agent for the detection of nrobilinogen, possibly together with bilirubin in body fluids comprises at least one stable benzene diazonium salt, the optionally polysubstituted phenyl radical of which contains in the o or p position to the diazonium group at least one polyatomic electron donor group with at least one mesomeric electron pair, the sum of the Hammett sigma values of all the substituents not exceeding 0.4; a solid or liquid organic or inorganic acid or acidic salt and optionally a wetting agent and/or stabiliser. The benzene diazonium salt may have general formula where one or both of R 1 and R 2 is or are polyatomic electron donor groups containing at least one mesomeric electron pair, and when R 1 and R 2 are different one of R 1 and R 2 may be hydrogen, halogen or a lower alkyl radical, and R 3 and R 4 which may be the same or different are hydrogen or halogen or groups which do not sterically hinder diazo coupling with nrobilinogen. The diagnostic agent may be impregnated into an absorbent carrier, for example filter paper, fleece or felts of polypropylene or polyesters, from a solution containing per 100 ml 0.05 to 5 gm diazonium salt, 2 to 30 gm acid, 0.1 to 3 gm wetting agent; or may be used as a solution. In the presence of both nrobilinogen and bilirubin two successive colour changes may take place in the test system.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2130559A DE2130559C3 (en) | 1971-06-19 | 1971-06-19 | Diagnostic means for the detection of urobihnogen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1343247A true GB1343247A (en) | 1974-01-10 |
Family
ID=5811257
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2781372A Expired GB1343247A (en) | 1971-06-19 | 1972-06-14 | Diagnostic agent for the detection of urobilinogen bodies in body fluids |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3853466A (en) |
| JP (1) | JPS5741693B1 (en) |
| AT (2) | AT317441B (en) |
| CA (1) | CA959389A (en) |
| CH (1) | CH564774A5 (en) |
| DD (1) | DD98763A5 (en) |
| DE (1) | DE2130559C3 (en) |
| DK (1) | DK143147C (en) |
| ES (1) | ES403875A1 (en) |
| FI (1) | FI53508C (en) |
| FR (1) | FR2158791A1 (en) |
| GB (1) | GB1343247A (en) |
| HU (1) | HU162948B (en) |
| IT (1) | IT956664B (en) |
| NL (1) | NL170773C (en) |
| SE (1) | SE394328B (en) |
| SU (1) | SU535914A3 (en) |
| ZA (1) | ZA724152B (en) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2521402C3 (en) * | 1975-05-14 | 1979-07-26 | Behringwerke Ag, 3550 Marburg | Diagnostic agent for the detection of urobilinogen |
| US4158546A (en) * | 1978-07-24 | 1979-06-19 | Miles Laboratories, Inc. | Composition, test device and method for determining the presence of urobilinogen in a test sample |
| DE2839931A1 (en) * | 1978-09-14 | 1980-03-27 | Behringwerke Ag | DIAGNOSTIC AGENT FOR DETECTING UROBILINOGEN |
| US4260579A (en) * | 1979-05-10 | 1981-04-07 | Miles Laboratories, Inc. | Device and method for simulating bilirubin in urine |
| US4311483A (en) * | 1979-06-18 | 1982-01-19 | Beckman Instruments, Inc. | Kinetic method for directly determining total bilirubin |
| US4246133A (en) * | 1979-06-22 | 1981-01-20 | Sherwood Medical Industries Inc. | Stabilized diazotized sulfanilic acid solutions |
| US4405718A (en) * | 1981-07-20 | 1983-09-20 | Miles Laboratories, Inc. | Method and composition for urobilinogen control standard |
| US4468467A (en) * | 1982-02-01 | 1984-08-28 | Eastman Kodak Company | Diazonium salt for bilirubin assay |
| JPS61223651A (en) * | 1985-03-29 | 1986-10-04 | Kyowa Medetsukusu Kk | Method for quantitative determination of bilirubin |
| US4816415A (en) * | 1987-05-29 | 1989-03-28 | Analytical Innovations, Inc. | Cannabinoid detection method |
| ES2079363T3 (en) * | 1988-06-09 | 1996-01-16 | Abbott Lab | METHOD AND DEVICE USING COVALENTLY IMMOBILIZED COLORED DYES. |
| JPH0270495U (en) * | 1988-11-17 | 1990-05-29 | ||
| US5736408A (en) * | 1994-11-23 | 1998-04-07 | Carter; Jesse M. | Method for the detection of urobilinogen in urine on an automated analyzer |
| US7936505B2 (en) * | 2006-08-28 | 2011-05-03 | Draper, Inc. | Tensioned projection screen |
| US8012761B2 (en) | 2006-12-14 | 2011-09-06 | Kimberly-Clark Worldwide, Inc. | Detection of formaldehyde in urine samples |
| US7846383B2 (en) | 2006-12-15 | 2010-12-07 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay device and absorbent article containing same |
| CN105954966B (en) | 2009-06-12 | 2018-11-27 | 迪瑞波有限公司 | Projection screen accessory, the method for building projection screen equipment and the method convenient for building projection screen equipment |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2854317A (en) * | 1950-08-08 | 1958-09-30 | Miles Lab | Method and composition for testing bilirubin in urine |
| US3511607A (en) * | 1967-10-06 | 1970-05-12 | Smithkline Corp | Laboratory reagent for assay of total bilirubin |
| DE1767931C3 (en) * | 1967-10-26 | 1973-09-27 | Boehringer Mannheim Gmbh, 6800 Mannheim | Diagnostic means and method for the detection of urobilinogen bodies |
| US3585001A (en) * | 1969-02-17 | 1971-06-15 | Miles Lab | Stabilized test device and process for detecting couplable compounds |
| US3585004A (en) * | 1969-03-21 | 1971-06-15 | Miles Lab | Test composition and device for detecting couplable compounds |
| US3652222A (en) * | 1969-04-07 | 1972-03-28 | American Monitor Corp | Bilirubin assay |
-
1971
- 1971-06-19 DE DE2130559A patent/DE2130559C3/en not_active Expired
-
1972
- 1972-05-11 DD DD162894A patent/DD98763A5/xx unknown
- 1972-06-13 HU HUBO1381A patent/HU162948B/hu unknown
- 1972-06-13 FI FI1685/72A patent/FI53508C/en active
- 1972-06-14 CH CH883772A patent/CH564774A5/xx not_active IP Right Cessation
- 1972-06-14 GB GB2781372A patent/GB1343247A/en not_active Expired
- 1972-06-14 US US00262923A patent/US3853466A/en not_active Expired - Lifetime
- 1972-06-15 ES ES403875A patent/ES403875A1/en not_active Expired
- 1972-06-15 FR FR7221551A patent/FR2158791A1/fr active Pending
- 1972-06-16 SU SU1799317A patent/SU535914A3/en active
- 1972-06-16 DK DK303372A patent/DK143147C/en not_active IP Right Cessation
- 1972-06-16 NL NLAANVRAGE7208232,A patent/NL170773C/en not_active IP Right Cessation
- 1972-06-16 SE SE7207961A patent/SE394328B/en unknown
- 1972-06-16 IT IT25819/72A patent/IT956664B/en active
- 1972-06-16 CA CA144,993A patent/CA959389A/en not_active Expired
- 1972-06-16 AT AT518072A patent/AT317441B/en not_active IP Right Cessation
- 1972-06-16 ZA ZA724152A patent/ZA724152B/en unknown
- 1972-06-16 AT AT841073A patent/AT322116B/en not_active IP Right Cessation
- 1972-06-19 JP JP47061253A patent/JPS5741693B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| SE394328B (en) | 1977-06-20 |
| SU535914A3 (en) | 1976-11-15 |
| ES403875A1 (en) | 1975-05-16 |
| AT317441B (en) | 1974-08-26 |
| NL170773C (en) | 1982-12-16 |
| AT322116B (en) | 1975-05-12 |
| DE2130559B2 (en) | 1973-04-26 |
| CA959389A (en) | 1974-12-17 |
| DE2130559C3 (en) | 1973-11-22 |
| FR2158791A1 (en) | 1973-06-15 |
| CH564774A5 (en) | 1975-07-31 |
| AU4354072A (en) | 1973-07-12 |
| DK143147C (en) | 1981-11-09 |
| DK143147B (en) | 1981-06-29 |
| ZA724152B (en) | 1973-04-25 |
| US3853466A (en) | 1974-12-10 |
| DD98763A5 (en) | 1973-07-05 |
| FI53508B (en) | 1978-01-31 |
| DE2130559A1 (en) | 1972-12-21 |
| NL7208232A (en) | 1972-12-21 |
| FI53508C (en) | 1978-05-10 |
| IT956664B (en) | 1973-10-10 |
| HU162948B (en) | 1973-05-28 |
| JPS5741693B1 (en) | 1982-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE20 | Patent expired after termination of 20 years |