GB1337389A - Pyrimidine derivatives - Google Patents
Pyrimidine derivativesInfo
- Publication number
- GB1337389A GB1337389A GB1337389DA GB1337389A GB 1337389 A GB1337389 A GB 1337389A GB 1337389D A GB1337389D A GB 1337389DA GB 1337389 A GB1337389 A GB 1337389A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- pyrimidine derivatives
- dec
- group
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Abstract
1337389 Pyrimidine derivatives IMPERIAL CHEMICAL INDUSTRIES Ltd 2 Dec 1970 [10 Dec 1969] 60323/69 Heading C2C Novel 2 - amino - 4 - hydroxy pyrimidines of formula wherein R<SP>1</SP> is an aryl or aralkyl group, R<SP>11</SP> is a C 1-8 alkyl group, and R 5 and R 6 (which are the same or different) are C 1-8 alkyl groups, and salts thereof, are prepared by reacting a guanidine of formula (or a salt thereof) with a keto ester of formula R 6 CO.CHR 5 .CO 2 R<SP>111</SP>, where R<SP>111</SP> is a C 1-8 alkyl group, in the presence of a base. The novel pyrimidines wherein R<SP>1</SP> is a benzyl or alkylbenzyl group may be reduced with H 2 in the presence of a hydrogenation catalyst to form a 2 - alkylamino - 4 - hydroxypyrimidine such as described in Specification 1,182,584 and 1,223,686.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB6032369 | 1969-12-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1337389A true GB1337389A (en) | 1973-11-14 |
Family
ID=10485429
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1337389D Expired GB1337389A (en) | 1969-12-10 | 1969-12-10 | Pyrimidine derivatives |
Country Status (6)
Country | Link |
---|---|
AU (1) | AU2314970A (en) |
BE (1) | BE760108A (en) |
DE (1) | DE2060846A1 (en) |
FR (1) | FR2073185A5 (en) |
GB (1) | GB1337389A (en) |
NL (1) | NL7017941A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005061458A3 (en) * | 2003-12-11 | 2005-10-13 | Memory Pharm Corp | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs |
US7655802B2 (en) | 2002-07-19 | 2010-02-02 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors, including aminoindazole and aminobenzofuran analogs |
US20110105797A1 (en) * | 2009-11-02 | 2011-05-05 | Tianjin Tiancheng Pharmaceutical Co., Ltd. | Creatinol sulfate and synthesis method thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU443171B2 (en) * | 1968-02-21 | 1973-11-27 | Imperial Chemical Industries Limited | Salts of pyrimidine derivatives |
-
1969
- 1969-12-10 GB GB1337389D patent/GB1337389A/en not_active Expired
-
1970
- 1970-12-09 BE BE760108A patent/BE760108A/en unknown
- 1970-12-09 AU AU23149/70A patent/AU2314970A/en not_active Expired
- 1970-12-09 NL NL7017941A patent/NL7017941A/xx unknown
- 1970-12-09 FR FR7044378A patent/FR2073185A5/en not_active Expired
- 1970-12-10 DE DE19702060846 patent/DE2060846A1/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7655802B2 (en) | 2002-07-19 | 2010-02-02 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors, including aminoindazole and aminobenzofuran analogs |
WO2005061458A3 (en) * | 2003-12-11 | 2005-10-13 | Memory Pharm Corp | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs |
US20110105797A1 (en) * | 2009-11-02 | 2011-05-05 | Tianjin Tiancheng Pharmaceutical Co., Ltd. | Creatinol sulfate and synthesis method thereof |
Also Published As
Publication number | Publication date |
---|---|
AU2314970A (en) | 1972-06-15 |
NL7017941A (en) | 1971-06-14 |
FR2073185A5 (en) | 1971-09-24 |
DE2060846A1 (en) | 1971-06-16 |
BE760108A (en) | 1971-06-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES267248A1 (en) | Pyrazolo-pyrimidines and process for preparing same | |
GB1337389A (en) | Pyrimidine derivatives | |
GB1527563A (en) | Propionic acid derivatives | |
GB1339748A (en) | Pyrimidine derivatives | |
GB1345930A (en) | Glassy zinc a-hydroxy diphosphonic acid products and their use as corrosion and scale inhibitors | |
GB1423266A (en) | 2-substituted thio-s-triazolo-1,5-a pyrimidines | |
GB1432125A (en) | Disinfectants | |
GB1451478A (en) | Phenylguanidine derivatives and processes for their preparation | |
GB1139813A (en) | New surface active agents, and their preparation and uses | |
GB1421580A (en) | Production of benzylamine derivatives | |
GB1269776A (en) | Epoxides and halohydrins and conversion thereof to alkanolamine derivatives | |
GB1426603A (en) | Amidine derivatives | |
GB1423047A (en) | Dyeing additives | |
GB1296371A (en) | ||
GB1185039A (en) | Pyrimidine Derivatives and Compositions containing them | |
IE39853L (en) | N'-(aminoacylaminophenyl)-acetamidine anthelmintictics. | |
GB1359523A (en) | Benzalacetone amidinohydrazone derivatives and the production thereof | |
GB1311703A (en) | Carbamates their manufacture and use as pesticides | |
GB1422722A (en) | Acrylic acid derivatives | |
GB1271016A (en) | Novel pyrrolidine derivatives, and processes for their preparation | |
GB1295838A (en) | ||
GB1336138A (en) | Process for the production of pyrimidine derivatives | |
ES430900A1 (en) | Substituted indanones | |
GB1375040A (en) | ||
GB1491679A (en) | Pharmaceutical compositions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |