GB1337105A - - Google Patents
Info
- Publication number
- GB1337105A GB1337105A GB3326172A GB3326172A GB1337105A GB 1337105 A GB1337105 A GB 1337105A GB 3326172 A GB3326172 A GB 3326172A GB 3326172 A GB3326172 A GB 3326172A GB 1337105 A GB1337105 A GB 1337105A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sodium
- amount
- sufficient amount
- solution
- preservative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 6
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 4
- 239000000243 solution Substances 0.000 abstract 4
- 239000011780 sodium chloride Substances 0.000 abstract 3
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 239000003755 preservative agent Substances 0.000 abstract 2
- 230000002335 preservative effect Effects 0.000 abstract 2
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 2
- JCZFHKOHTJMENG-VKHMYHEASA-N (2s)-2-nitrosopentanedioic acid Chemical compound OC(=O)CC[C@H](N=O)C(O)=O JCZFHKOHTJMENG-VKHMYHEASA-N 0.000 abstract 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 abstract 1
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 abstract 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 abstract 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 abstract 1
- 229920001479 Hydroxyethyl methyl cellulose Polymers 0.000 abstract 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 abstract 1
- 239000004372 Polyvinyl alcohol Substances 0.000 abstract 1
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 abstract 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal acetate Chemical class 0.000 abstract 1
- 229960000686 benzalkonium chloride Drugs 0.000 abstract 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
- 239000006177 biological buffer Substances 0.000 abstract 1
- 239000000872 buffer Substances 0.000 abstract 1
- 229960003260 chlorhexidine Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940050410 gluconate Drugs 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 229940049920 malate Drugs 0.000 abstract 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N malic acid Chemical compound OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 abstract 1
- 239000001923 methylcellulose Substances 0.000 abstract 1
- 235000010981 methylcellulose Nutrition 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- KHPXUQMNIQBQEV-UHFFFAOYSA-N oxaloacetic acid Chemical compound OC(=O)CC(=O)C(O)=O KHPXUQMNIQBQEV-UHFFFAOYSA-N 0.000 abstract 1
- 229920002451 polyvinyl alcohol Polymers 0.000 abstract 1
- 239000001103 potassium chloride Substances 0.000 abstract 1
- 235000011164 potassium chloride Nutrition 0.000 abstract 1
- 235000017281 sodium acetate Nutrition 0.000 abstract 1
- 239000001632 sodium acetate Substances 0.000 abstract 1
- 229940037001 sodium edetate Drugs 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 abstract 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00166286A US3843782A (en) | 1971-07-26 | 1971-07-26 | Eye solution and method of using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1337105A true GB1337105A (https=) | 1973-11-14 |
Family
ID=22602617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3326172A Expired GB1337105A (https=) | 1971-07-26 | 1972-07-17 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US3843782A (https=) |
| AU (1) | AU4481372A (https=) |
| CA (1) | CA943863A (https=) |
| GB (1) | GB1337105A (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2169508A (en) * | 1985-01-11 | 1986-07-16 | Smith & Nephew Ass | Ophthalmic solutions containing hydroxyethyl cellulose |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5428810A (en) * | 1977-08-01 | 1979-03-03 | American Home Prod | Pharmaceutical composition for eye disease containing 1*33dioxoo1hhbenzo *d * e* isoquinolinee2*3h**acetic acid |
| US4120949A (en) * | 1977-10-05 | 1978-10-17 | Cooper Laboratories, Inc. | Ophthalmic solution |
| US4131651A (en) * | 1977-10-25 | 1978-12-26 | Barnes-Hind Pharmaceuticals, Inc. | Treatment of dry eye |
| US4199567A (en) * | 1979-01-02 | 1980-04-22 | Burton, Parsons & Company, Inc. | Method for imparting freeze stability to chlorhexidine-containing medicaments |
| US4409205A (en) * | 1979-03-05 | 1983-10-11 | Cooper Laboratories, Inc. | Ophthalmic solution |
| US4271144A (en) * | 1979-06-06 | 1981-06-02 | Holles Laboratories, Inc. | Dextran composition for controlling corneal hydration |
| US4597965A (en) * | 1979-06-06 | 1986-07-01 | Holles Laboratories, Inc. | Method and composition for controlling corneal hydration |
| EP0055515B1 (en) | 1980-12-18 | 1985-02-20 | Smith and Nephew Associated Companies p.l.c. | Lens sterilising solutions and their use |
| US4443432A (en) * | 1981-10-05 | 1984-04-17 | Alcon Laboratories, Inc. | Ophthmalic irrigating solution |
| US4550022A (en) * | 1981-10-05 | 1985-10-29 | Alcon Laboratories, Inc. | Tissue irrigating solution |
| US4581226A (en) * | 1983-04-07 | 1986-04-08 | Dillon Richard S | Method of treating sensitive animal tissue with a specially processed seawater solution |
| AU4500085A (en) * | 1984-06-22 | 1986-01-24 | R.L. Veech | Electrolyte solutions containing polyanionic materials |
| US5209927A (en) * | 1985-01-23 | 1993-05-11 | Alcon Laboratories, Inc. | Ophthalmic solution |
| US4826871A (en) * | 1985-03-13 | 1989-05-02 | Gressel Philip D | Topical ophthalmic compositions containing one or more retinoids |
| CA1263606A (en) * | 1985-05-29 | 1989-12-05 | Jeffrey P. Gilbard | Non-toxic opthalmic preparations |
| US4966773A (en) * | 1986-11-25 | 1990-10-30 | Alcon Laboratories, Inc. | Topical ophthalmic compositions containing microfine retinoid particles |
| US5500230A (en) * | 1987-01-23 | 1996-03-19 | The General Hospital Corporation | Method for treatment of glaucoma with nitrogen containing guanylate cyclase activators |
| EP0362277A4 (en) * | 1987-06-01 | 1990-11-28 | Allergan, Inc | Preservative free ophthalmic ointments |
| GR1000176B (el) * | 1989-01-10 | 1991-12-30 | Gerasimos Antypas | Αντίδοτο υδρο?είου. |
| CA2159706A1 (en) * | 1994-02-04 | 1995-08-10 | Peter John Mcdonnell | Method for preventing keratocyte loss |
| US5683709A (en) * | 1994-05-05 | 1997-11-04 | Ciba Vision Corporation | Poly(benzalkonium salt) as an anti-microbial agent for aqueous drug compositions |
| DK0999825T3 (da) | 1997-07-29 | 2004-02-09 | Alcon Lab Inc | Oftalmiske sammensætninger indeholdende galactomannanpolymerer og borater |
| DE102008064065B9 (de) * | 2008-12-19 | 2011-01-05 | Fluoron Gmbh | Farbstofflösung |
| TWI544922B (zh) | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物 |
-
1971
- 1971-07-26 US US00166286A patent/US3843782A/en not_active Expired - Lifetime
-
1972
- 1972-07-17 GB GB3326172A patent/GB1337105A/en not_active Expired
- 1972-07-20 AU AU44813/72A patent/AU4481372A/en not_active Expired
- 1972-07-25 CA CA147,874A patent/CA943863A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2169508A (en) * | 1985-01-11 | 1986-07-16 | Smith & Nephew Ass | Ophthalmic solutions containing hydroxyethyl cellulose |
Also Published As
| Publication number | Publication date |
|---|---|
| US3843782A (en) | 1974-10-22 |
| CA943863A (en) | 1974-03-19 |
| AU4481372A (en) | 1974-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |