GB1336155A - Preparation of 7-amino-cephalo-sporanic acid derivatives - Google Patents
Preparation of 7-amino-cephalo-sporanic acid derivativesInfo
- Publication number
- GB1336155A GB1336155A GB5375370A GB5375370A GB1336155A GB 1336155 A GB1336155 A GB 1336155A GB 5375370 A GB5375370 A GB 5375370A GB 5375370 A GB5375370 A GB 5375370A GB 1336155 A GB1336155 A GB 1336155A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- formula
- preparation
- acid derivatives
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical class S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 6
- -1 azido, thiadiazolylthio, oxadiazolylthio Chemical group 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- IJOOHPMOJXWVHK-UHFFFAOYSA-N chlorotrimethylsilane Chemical compound C[Si](C)(C)Cl IJOOHPMOJXWVHK-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- FCSKOFQQCWLGMV-UHFFFAOYSA-N 5-{5-[2-chloro-4-(4,5-dihydro-1,3-oxazol-2-yl)phenoxy]pentyl}-3-methylisoxazole Chemical compound O1N=C(C)C=C1CCCCCOC1=CC=C(C=2OCCN=2)C=C1Cl FCSKOFQQCWLGMV-UHFFFAOYSA-N 0.000 abstract 1
- FKLJPTJMIBLJAV-UHFFFAOYSA-N Compound IV Chemical compound O1N=C(C)C=C1CCCCCCCOC1=CC=C(C=2OCCN=2)C=C1 FKLJPTJMIBLJAV-UHFFFAOYSA-N 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- NVRSPIKUPKOSIY-UHFFFAOYSA-N chembl1743348 Chemical compound CC=1N=NOC=1O NVRSPIKUPKOSIY-UHFFFAOYSA-N 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 125000001715 oxadiazolyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
- 125000001113 thiadiazolyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9242169 | 1969-11-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1336155A true GB1336155A (en) | 1973-11-07 |
Family
ID=14053939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5375370A Expired GB1336155A (en) | 1969-11-17 | 1970-11-11 | Preparation of 7-amino-cephalo-sporanic acid derivatives |
Country Status (10)
| Country | Link |
|---|---|
| AT (1) | AT309676B (enrdf_load_stackoverflow) |
| BE (1) | BE758587A (enrdf_load_stackoverflow) |
| CH (1) | CH569026A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2055796C2 (enrdf_load_stackoverflow) |
| DK (1) | DK147597C (enrdf_load_stackoverflow) |
| ES (1) | ES385581A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2069363A5 (enrdf_load_stackoverflow) |
| GB (1) | GB1336155A (enrdf_load_stackoverflow) |
| NL (1) | NL171708C (enrdf_load_stackoverflow) |
| SE (1) | SE374923B (enrdf_load_stackoverflow) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE793037A (fr) * | 1971-12-23 | 1973-06-20 | Fujisawa Pharmaceutical Co | Procede de preparation de derives d'acide 7-acylamino-3-substitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus |
| GB1414324A (en) * | 1971-12-23 | 1975-11-19 | Fujisawa Pharmaceutical Co | Process for preparing 7-acylamino-3-substituted-3-cephem-4- carboxylic acid derivatives |
| GB1492435A (en) * | 1974-08-30 | 1977-11-16 | Squibb & Sons Inc | Cephalosporins |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL150798B (nl) * | 1967-08-07 | 1976-09-15 | Koninklijke Gist Spiritus | Werkwijze voor de bereiding van 7-aminocefalosoranzuur en derivaten daarvan. |
| CH527215A (de) * | 1967-04-15 | 1972-08-31 | Fujisawa Pharmaceutical Co | Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten |
-
0
- BE BE758587D patent/BE758587A/xx not_active IP Right Cessation
-
1970
- 1970-11-11 GB GB5375370A patent/GB1336155A/en not_active Expired
- 1970-11-13 DE DE19702055796 patent/DE2055796C2/de not_active Expired
- 1970-11-13 FR FR7040707A patent/FR2069363A5/fr not_active Expired
- 1970-11-16 ES ES385581A patent/ES385581A1/es not_active Expired
- 1970-11-16 AT AT1028670A patent/AT309676B/de active
- 1970-11-16 SE SE1544970A patent/SE374923B/xx unknown
- 1970-11-17 NL NL7016844A patent/NL171708C/xx not_active IP Right Cessation
- 1970-11-17 DK DK583670A patent/DK147597C/da not_active IP Right Cessation
- 1970-11-17 CH CH1708070A patent/CH569026A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2055796C2 (de) | 1982-04-01 |
| AT309676B (de) | 1973-08-27 |
| CH569026A5 (enrdf_load_stackoverflow) | 1975-11-14 |
| DK147597C (da) | 1985-04-22 |
| SE374923B (enrdf_load_stackoverflow) | 1975-03-24 |
| FR2069363A5 (enrdf_load_stackoverflow) | 1971-09-03 |
| NL7016844A (enrdf_load_stackoverflow) | 1971-05-19 |
| ES385581A1 (es) | 1973-08-16 |
| DK147597B (da) | 1984-10-15 |
| BE758587A (fr) | 1971-05-06 |
| DE2055796A1 (de) | 1971-05-27 |
| NL171708B (nl) | 1982-12-01 |
| NL171708C (nl) | 1983-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |