GB1334633A - Quinazoline compounds and methods for their production - Google Patents
Quinazoline compounds and methods for their productionInfo
- Publication number
- GB1334633A GB1334633A GB1623072A GB1334633DA GB1334633A GB 1334633 A GB1334633 A GB 1334633A GB 1623072 A GB1623072 A GB 1623072A GB 1334633D A GB1334633D A GB 1334633DA GB 1334633 A GB1334633 A GB 1334633A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- production
- methods
- phenyl
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 3
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- -1 biphenylyl Chemical group 0.000 abstract 2
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- QGBSISYHAICWAH-UHFFFAOYSA-N dicyandiamide Chemical compound NC(N)=NC#N QGBSISYHAICWAH-UHFFFAOYSA-N 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- XELRMPRLCPFTBH-UHFFFAOYSA-N quinazoline-2,4-diamine Chemical class C1=CC=CC2=NC(N)=NC(N)=C21 XELRMPRLCPFTBH-UHFFFAOYSA-N 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000001174 sulfone group Chemical group 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 150000003568 thioethers Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1623072 | 1972-04-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1334633A true GB1334633A (en) | 1973-10-24 |
Family
ID=10073534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1623072A Expired GB1334633A (en) | 1972-04-07 | 1972-04-07 | Quinazoline compounds and methods for their production |
Country Status (11)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2723247C2 (de) * | 1977-05-24 | 1982-09-16 | Hoechst Ag, 6000 Frankfurt | Verfahren zur kontinuierlichen Herstellung von 3-Nitro-4-acetylaminotoluol |
| US4287341A (en) * | 1979-11-01 | 1981-09-01 | Pfizer Inc. | Alkoxy-substituted-6-chloro-quinazoline-2,4-diones |
| JPS5943478U (ja) * | 1982-09-17 | 1984-03-22 | 株式会社東芝 | エスカレ−タの踏段 |
| DE19746540A1 (de) | 1997-10-22 | 1999-04-29 | Bayer Ag | S-(4-Biphenyl)-thioschwefelsäuren und ihre Salze, Verfahren zu deren Herstellung und die Herstellung von 4-Mercaptobiphenylen |
| CN108938639B (zh) * | 2017-05-17 | 2021-01-08 | 浙江立恩生物科技有限公司 | 化合物nsc305780在制备治疗或预防流感病毒的药物中的应用 |
| GB2626567A (en) * | 2023-01-26 | 2024-07-31 | De Montfort Univ | Quinazoline derivatives for use as a medicament |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2953567A (en) * | 1956-11-23 | 1960-09-20 | Burroughs Wellcome Co | 5-phenylmercaptopyrimidines and method |
| FR1490622A (fr) * | 1963-09-20 | 1967-08-04 | Parke Davis & Co | Nouveaux dérivés de 2, 4-diaminoqunazoline et procédés pour leur préparation |
| GB1143290A (en) * | 1967-12-08 | 1969-02-19 | Parke Davis & Co | New 2,4-diamino-6-quinazolinesulfonamide compounds and methods for their production |
| DE1795271A1 (de) * | 1968-08-31 | 1971-12-30 | Bayer Ag | Verfahren zur Herstellung von substituierten 4-Aminochinazolinen |
| US3663706A (en) * | 1969-09-29 | 1972-05-16 | Pfizer | Use of 2,4-diaminoquinazolines as hypotensive agents |
-
1972
- 1972-04-07 GB GB1623072A patent/GB1334633A/en not_active Expired
-
1973
- 1973-01-17 US US00324276A patent/US3853873A/en not_active Expired - Lifetime
- 1973-04-05 AU AU54137/73A patent/AU467250B2/en not_active Expired
- 1973-04-05 AR AR247407A patent/AR196759A1/es active
- 1973-04-05 JP JP48038354A patent/JPS4913188A/ja active Pending
- 1973-04-05 NL NL7304751A patent/NL7304751A/xx not_active Application Discontinuation
- 1973-04-05 FR FR7312274A patent/FR2182937B1/fr not_active Expired
- 1973-04-05 ZA ZA732393A patent/ZA732393B/xx unknown
- 1973-04-05 BE BE129689A patent/BE797824A/xx unknown
- 1973-04-05 DE DE2317142A patent/DE2317142B2/de not_active Withdrawn
- 1973-04-06 PH PH14497*UA patent/PH9479A/en unknown
- 1973-12-27 AR AR251710A patent/AR196846A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| AU5413773A (en) | 1974-10-10 |
| FR2182937B1 (enrdf_load_stackoverflow) | 1977-04-08 |
| AU467250B2 (en) | 1975-11-27 |
| DE2317142A1 (de) | 1973-10-18 |
| JPS4913188A (enrdf_load_stackoverflow) | 1974-02-05 |
| AR196846A1 (es) | 1974-02-19 |
| BE797824A (fr) | 1973-07-31 |
| ZA732393B (en) | 1974-11-27 |
| FR2182937A1 (enrdf_load_stackoverflow) | 1973-12-14 |
| US3853873A (en) | 1974-12-10 |
| AR196759A1 (es) | 1974-02-19 |
| DE2317142B2 (de) | 1979-02-08 |
| NL7304751A (enrdf_load_stackoverflow) | 1973-10-09 |
| PH9479A (en) | 1976-01-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |