GB1333358A - Substituted oxazino 5,6-e indoles their process of preparation and their therapeutic application - Google Patents
Substituted oxazino 5,6-e indoles their process of preparation and their therapeutic applicationInfo
- Publication number
- GB1333358A GB1333358A GB2537172A GB2537172A GB1333358A GB 1333358 A GB1333358 A GB 1333358A GB 2537172 A GB2537172 A GB 2537172A GB 2537172 A GB2537172 A GB 2537172A GB 1333358 A GB1333358 A GB 1333358A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oxazino
- indoles
- substituted
- preparation
- therapeutic application
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 150000002475 indoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 101100037762 Caenorhabditis elegans rnh-2 gene Proteins 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000003555 analeptic effect Effects 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- BSNHKSUAAMJXBB-UHFFFAOYSA-N ethyl 5-hydroxy-2-methyl-1h-indole-3-carboxylate Chemical compound C1=C(O)C=C2C(C(=O)OCC)=C(C)NC2=C1 BSNHKSUAAMJXBB-UHFFFAOYSA-N 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- TXSPITKKVMLDDL-UHFFFAOYSA-N pyrrolo[2,3-f][2,1]benzoxazine Chemical class C1=CC2=NOC=CC2=C2C1=CC=N2 TXSPITKKVMLDDL-UHFFFAOYSA-N 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7120708A FR2140280B1 (enExample) | 1971-06-08 | 1971-06-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1333358A true GB1333358A (en) | 1973-10-10 |
Family
ID=9078293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2537172A Expired GB1333358A (en) | 1971-06-08 | 1972-05-31 | Substituted oxazino 5,6-e indoles their process of preparation and their therapeutic application |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US3852284A (enExample) |
| JP (1) | JPS5238B1 (enExample) |
| BE (1) | BE784197A (enExample) |
| CA (1) | CA989836A (enExample) |
| CH (1) | CH533131A (enExample) |
| DE (1) | DE2227489A1 (enExample) |
| ES (1) | ES403547A1 (enExample) |
| FR (1) | FR2140280B1 (enExample) |
| GB (1) | GB1333358A (enExample) |
| IT (1) | IT1051602B (enExample) |
| LU (1) | LU65464A1 (enExample) |
| NL (1) | NL160565C (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4012511A (en) * | 1974-05-28 | 1977-03-15 | Ayerst Mckenna & Harrison Ltd. | Oxazinoindole derivatives useful as antidepressants |
| DE3633861A1 (de) * | 1986-10-04 | 1988-04-07 | Thomae Gmbh Dr K | Neue imidazo-benzoxazinone, ihre herstellung und diese verbindungen enthaltende arzneimittel |
-
1971
- 1971-06-08 FR FR7120708A patent/FR2140280B1/fr not_active Expired
-
1972
- 1972-05-31 BE BE784197A patent/BE784197A/xx unknown
- 1972-05-31 GB GB2537172A patent/GB1333358A/en not_active Expired
- 1972-06-02 CH CH821372A patent/CH533131A/fr not_active IP Right Cessation
- 1972-06-05 LU LU65464A patent/LU65464A1/xx unknown
- 1972-06-06 DE DE19722227489 patent/DE2227489A1/de active Pending
- 1972-06-06 ES ES403547A patent/ES403547A1/es not_active Expired
- 1972-06-06 US US00260298A patent/US3852284A/en not_active Expired - Lifetime
- 1972-06-07 NL NL7207695.A patent/NL160565C/xx active
- 1972-06-07 JP JP47056119A patent/JPS5238B1/ja active Pending
- 1972-06-07 IT IT68803/72A patent/IT1051602B/it active
- 1972-06-08 CA CA144,274A patent/CA989836A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| LU65464A1 (enExample) | 1973-01-22 |
| FR2140280B1 (enExample) | 1974-08-23 |
| JPS5238B1 (enExample) | 1977-01-05 |
| NL160565C (nl) | 1979-11-15 |
| IT1051602B (it) | 1981-05-20 |
| ES403547A1 (es) | 1975-05-01 |
| BE784197A (fr) | 1972-11-30 |
| CH533131A (fr) | 1973-01-31 |
| CA989836A (fr) | 1976-05-25 |
| FR2140280A1 (enExample) | 1973-01-19 |
| NL160565B (nl) | 1979-06-15 |
| NL7207695A (enExample) | 1972-12-12 |
| DE2227489A1 (de) | 1972-12-28 |
| US3852284A (en) | 1974-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |