GB1328979A - Dicarbonyl dicyano and carbonylcyano compounds - Google Patents
Dicarbonyl dicyano and carbonylcyano compoundsInfo
- Publication number
- GB1328979A GB1328979A GB4401070A GB4401070A GB1328979A GB 1328979 A GB1328979 A GB 1328979A GB 4401070 A GB4401070 A GB 4401070A GB 4401070 A GB4401070 A GB 4401070A GB 1328979 A GB1328979 A GB 1328979A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oxo
- compounds
- sulphide
- dioxo
- free
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 7
- 125000004989 dicarbonyl group Chemical group 0.000 title abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 5
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- -1 aliphatic amines Chemical class 0.000 abstract 3
- 239000004215 Carbon black (E152) Substances 0.000 abstract 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 2
- 239000002585 base Substances 0.000 abstract 2
- DGAODIKUWGRDBO-UHFFFAOYSA-N butanethioic s-acid Chemical compound CCCC(O)=S DGAODIKUWGRDBO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 229930195733 hydrocarbon Natural products 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 239000007858 starting material Substances 0.000 abstract 2
- DTPYZUHERNIIBR-UHFFFAOYSA-N 1-(4-bromophenyl)hexane-1,3-dione octane-3,5-dione Chemical compound O=C(CC)CC(CCC)=O.BrC1=CC=C(C=C1)C(CC(CCC)=O)=O DTPYZUHERNIIBR-UHFFFAOYSA-N 0.000 abstract 1
- MOMFXATYAINJML-UHFFFAOYSA-N 2-Acetylthiazole Chemical group CC(=O)C1=NC=CS1 MOMFXATYAINJML-UHFFFAOYSA-N 0.000 abstract 1
- FKJSFKCZZIXQIP-UHFFFAOYSA-N 2-bromo-1-(4-bromophenyl)ethanone Chemical compound BrCC(=O)C1=CC=C(Br)C=C1 FKJSFKCZZIXQIP-UHFFFAOYSA-N 0.000 abstract 1
- RGHQKFQZGLKBCF-UHFFFAOYSA-N 2-bromoethyl acetate Chemical compound CC(=O)OCCBr RGHQKFQZGLKBCF-UHFFFAOYSA-N 0.000 abstract 1
- BNBOUFHCTIFWHN-UHFFFAOYSA-N 3-bromobutan-2-one Chemical compound CC(Br)C(C)=O BNBOUFHCTIFWHN-UHFFFAOYSA-N 0.000 abstract 1
- UQOOCVASVGYQCY-UHFFFAOYSA-N 3-methylheptane-2,4-dione Chemical compound CCCC(=O)C(C)C(C)=O UQOOCVASVGYQCY-UHFFFAOYSA-N 0.000 abstract 1
- 101100188552 Arabidopsis thaliana OCT3 gene Proteins 0.000 abstract 1
- YJOAANYBBUWXFG-UHFFFAOYSA-N C(C)OC(CCCCC(=O)SC(CCCCC(OCC)=O)=O)=O Chemical compound C(C)OC(CCCCC(=O)SC(CCCCC(OCC)=O)=O)=O YJOAANYBBUWXFG-UHFFFAOYSA-N 0.000 abstract 1
- CRVXLMAQLHMDSC-UHFFFAOYSA-N C(CCC)(=O)CCC(CSCC(CCC(CCC)=O)=O)=O Chemical compound C(CCC)(=O)CCC(CSCC(CCC(CCC)=O)=O)=O CRVXLMAQLHMDSC-UHFFFAOYSA-N 0.000 abstract 1
- OAOQREIPWDFOTM-UHFFFAOYSA-N CC(C(C)=O)CCCC(=O)SC(CCCC(C(C)=O)C)=O Chemical compound CC(C(C)=O)CCCC(=O)SC(CCCC(C(C)=O)C)=O OAOQREIPWDFOTM-UHFFFAOYSA-N 0.000 abstract 1
- JGFZNNIVVJXRND-UHFFFAOYSA-N N,N-Diisopropylethylamine (DIPEA) Chemical class CCN(C(C)C)C(C)C JGFZNNIVVJXRND-UHFFFAOYSA-N 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- KWACQFQIFSBXOK-UHFFFAOYSA-N S-(2-methyl-3-oxobutanoyl) 2-methyl-3-oxobutanethioate Chemical compound CC(C(C)=O)C(=O)SC(=O)C(C(C)=O)C KWACQFQIFSBXOK-UHFFFAOYSA-N 0.000 abstract 1
- AFJYFSYGXQEDKF-UHFFFAOYSA-N S-[6-(4-bromophenyl)-6-oxohexanoyl] 6-(4-bromophenyl)-6-oxohexanethioate Chemical compound BrC1=CC=C(C=C1)C(CCCCC(=O)SC(CCCCC(C1=CC=C(C=C1)Br)=O)=O)=O AFJYFSYGXQEDKF-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002015 acyclic group Chemical group 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000719 anti-leukaemic effect Effects 0.000 abstract 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical class 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- ZHDUQUQKEAZVPG-UHFFFAOYSA-N ethyl 2-methyl-3-oxohexanoate Chemical compound CCCC(=O)C(C)C(=O)OCC ZHDUQUQKEAZVPG-UHFFFAOYSA-N 0.000 abstract 1
- KQWWVLVLVYYYDT-UHFFFAOYSA-N ethyl 3-oxohexanoate Chemical compound CCCC(=O)CC(=O)OCC KQWWVLVLVYYYDT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229910003002 lithium salt Inorganic materials 0.000 abstract 1
- 159000000002 lithium salts Chemical class 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- APARIAFVBSRIHF-UHFFFAOYSA-M sodium;methanethioate Chemical compound [Na+].[O-]C=S APARIAFVBSRIHF-UHFFFAOYSA-M 0.000 abstract 1
- 230000003096 thymolvtic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/807—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen all halogen atoms bound to the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/12—Ketones containing more than one keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/185—Saturated compounds containing keto groups bound to acyclic carbon atoms containing —CHO groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1411769A CH555791A (de) | 1969-09-18 | 1969-09-18 | Verfahren zur entschwefelung organischer verbindungen. |
| CH1495769 | 1969-10-03 | ||
| CH1634569 | 1969-11-03 | ||
| CH1924469A CH565201A5 (en) | 1969-09-18 | 1969-12-24 | Dicarbonyl compds and 21-alkanoyl-pregna- - 4-ene-3, 20-diones prepn |
| CH328670 | 1970-03-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1328979A true GB1328979A (en) | 1973-09-05 |
Family
ID=27509125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4401070A Expired GB1328979A (en) | 1969-09-18 | 1970-09-15 | Dicarbonyl dicyano and carbonylcyano compounds |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE756257A (enrdf_load_stackoverflow) |
| CA (1) | CA928703A (enrdf_load_stackoverflow) |
| DE (1) | DE2044831A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2070077A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1328979A (enrdf_load_stackoverflow) |
| NL (1) | NL7013783A (enrdf_load_stackoverflow) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2231374B1 (enrdf_load_stackoverflow) | 1973-05-30 | 1976-10-22 | Jouveinal Sa | |
| US4177268A (en) * | 1973-05-30 | 1979-12-04 | Jouveinal S.A. | Method of alleviating inflammation by administration of dexamethasone derivatives |
| FR2529894B2 (fr) * | 1981-07-30 | 1986-07-25 | Jouveinal | Steroides esterifies en la position 17 et thio-esterifies en la position 21 et leur application comme medicament |
| FR2510582B1 (fr) * | 1981-07-30 | 1986-05-30 | Sipsy | Steroides esterifies en la position 17 et thio-esterifies en la position 21, leur procede de preparation et leur application comme medicament |
-
1970
- 1970-09-10 DE DE19702044831 patent/DE2044831A1/de active Pending
- 1970-09-11 CA CA092885A patent/CA928703A/en not_active Expired
- 1970-09-15 FR FR7033335A patent/FR2070077A1/fr not_active Withdrawn
- 1970-09-15 GB GB4401070A patent/GB1328979A/en not_active Expired
- 1970-09-17 NL NL7013783A patent/NL7013783A/xx unknown
- 1970-09-17 BE BE756257D patent/BE756257A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE756257A (fr) | 1971-03-17 |
| CA928703A (en) | 1973-06-19 |
| NL7013783A (enrdf_load_stackoverflow) | 1971-03-22 |
| DE2044831A1 (enrdf_load_stackoverflow) | 1971-03-25 |
| FR2070077A1 (enrdf_load_stackoverflow) | 1971-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |