GB1327691A - Phenyl cyclohexenylamines and the preparation thereof - Google Patents
Phenyl cyclohexenylamines and the preparation thereofInfo
- Publication number
- GB1327691A GB1327691A GB3451071A GB3451071A GB1327691A GB 1327691 A GB1327691 A GB 1327691A GB 3451071 A GB3451071 A GB 3451071A GB 3451071 A GB3451071 A GB 3451071A GB 1327691 A GB1327691 A GB 1327691A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- ring
- compounds
- formulμ
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NMHAAZGGTJQEFL-UHFFFAOYSA-N n-(cyclohexen-1-yl)aniline Chemical class C1CCCC(NC=2C=CC=CC=2)=C1 NMHAAZGGTJQEFL-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052799 carbon Inorganic materials 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000006719 (C6-C10) aryl (C1-C6) alkyl group Chemical group 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005115 alkyl carbamoyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 125000003435 aroyl group Chemical group 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 239000003874 central nervous system depressant Substances 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- TXTHKGMZDDTZFD-UHFFFAOYSA-N n-cyclohexylaniline Chemical class C1CCCCC1NC1=CC=CC=C1 TXTHKGMZDDTZFD-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- -1 pyrrolidino, piperidino Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6857270A | 1970-08-31 | 1970-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1327691A true GB1327691A (en) | 1973-08-22 |
Family
ID=22083404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3451071A Expired GB1327691A (en) | 1970-08-31 | 1971-07-22 | Phenyl cyclohexenylamines and the preparation thereof |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE772009A (https=) |
| DE (1) | DE2142480A1 (https=) |
| FR (1) | FR2103646B1 (https=) |
| GB (1) | GB1327691A (https=) |
| NL (1) | NL7111975A (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0063793A3 (en) * | 1981-04-27 | 1983-01-19 | Hoechst-Roussel Pharmaceuticals Incorporated | (arylmethyl)aryl-amino-cyclohexanols, -cyclohexanes, -cyclohexenes and intermediates thereof, a process for preparing the same and their use as medicaments |
| US4975445A (en) * | 1989-12-06 | 1990-12-04 | Warner-Lambert Company | Substituted cyclohexenes as central nervous system agents |
| EP0982026A3 (en) * | 1998-08-18 | 2001-06-13 | F. Hoffmann-La Roche Ag | Use of aryl-cyclohexylamine derivatives in the manufacture of NMDA receptor blockers |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3965180A (en) * | 1971-11-01 | 1976-06-22 | The Upjohn Company | 4'-Fluoro-4-{[4-(phenyl)-4-alkoxy-cyclo-hexyl]amino}butyrophenones and the salts thereof |
-
1971
- 1971-07-22 GB GB3451071A patent/GB1327691A/en not_active Expired
- 1971-08-25 DE DE19712142480 patent/DE2142480A1/de active Pending
- 1971-08-30 FR FR7131381A patent/FR2103646B1/fr not_active Expired
- 1971-08-31 BE BE772009A patent/BE772009A/xx unknown
- 1971-08-31 NL NL7111975A patent/NL7111975A/xx unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0063793A3 (en) * | 1981-04-27 | 1983-01-19 | Hoechst-Roussel Pharmaceuticals Incorporated | (arylmethyl)aryl-amino-cyclohexanols, -cyclohexanes, -cyclohexenes and intermediates thereof, a process for preparing the same and their use as medicaments |
| US4975445A (en) * | 1989-12-06 | 1990-12-04 | Warner-Lambert Company | Substituted cyclohexenes as central nervous system agents |
| EP0431579A3 (en) * | 1989-12-06 | 1991-12-11 | Warner-Lambert Company | Substituted cyclohexenes as central nervous system agents |
| EP0982026A3 (en) * | 1998-08-18 | 2001-06-13 | F. Hoffmann-La Roche Ag | Use of aryl-cyclohexylamine derivatives in the manufacture of NMDA receptor blockers |
Also Published As
| Publication number | Publication date |
|---|---|
| BE772009A (fr) | 1972-02-29 |
| FR2103646B1 (https=) | 1975-02-07 |
| FR2103646A1 (https=) | 1972-04-14 |
| DE2142480A1 (https=) | 1972-03-09 |
| NL7111975A (https=) | 1972-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |