GB1325943A - Mono-acetyl derivatives of antibiotic sf 837 and sf 837-a2 substances and production thereof - Google Patents
Mono-acetyl derivatives of antibiotic sf 837 and sf 837-a2 substances and production thereofInfo
- Publication number
- GB1325943A GB1325943A GB1134071*[A GB1134071A GB1325943A GB 1325943 A GB1325943 A GB 1325943A GB 1134071 A GB1134071 A GB 1134071A GB 1325943 A GB1325943 A GB 1325943A
- Authority
- GB
- United Kingdom
- Prior art keywords
- mono
- acetates
- antibiotic
- acetate
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 3
- TYYIFWXTQAQRHI-MDWYKHENSA-N [(2s,3s,4r,6s)-6-[(2r,3s,4r,5r,6s)-4-(dimethylamino)-5-hydroxy-6-[[(4r,5s,6s,7r,9r,10r,11e,13e,16r)-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-4-propanoyloxy-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyl Chemical compound C1[C@](O)(C)[C@@H](OC(=O)CCC)[C@H](C)O[C@H]1O[C@H]1[C@H](N(C)C)[C@@H](O)[C@H](O[C@@H]2[C@H]([C@H](OC(=O)CC)CC(=O)O[C@H](C)C/C=C/C=C/[C@H](O)[C@H](C)C[C@@H]2CC=O)OC)O[C@@H]1C TYYIFWXTQAQRHI-MDWYKHENSA-N 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- DMUAPQTXSSNEDD-QALJCMCCSA-N Midecamycin Chemical compound C1[C@](O)(C)[C@@H](OC(=O)CC)[C@H](C)O[C@H]1O[C@H]1[C@H](N(C)C)[C@@H](O)[C@H](O[C@@H]2[C@H]([C@H](OC(=O)CC)CC(=O)O[C@H](C)C/C=C/C=C/[C@H](O)[C@H](C)C[C@@H]2CC=O)OC)O[C@@H]1C DMUAPQTXSSNEDD-QALJCMCCSA-N 0.000 abstract 4
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 239000003242 anti bacterial agent Substances 0.000 abstract 3
- 229940088710 antibiotic agent Drugs 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 2
- 239000007858 starting material Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
- DKPFZGUDAPQIHT-UHFFFAOYSA-N Butyl acetate Natural products CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Natural products CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3745670 | 1970-05-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1325943A true GB1325943A (en) | 1973-08-08 |
Family
ID=12498005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1134071*[A Expired GB1325943A (en) | 1970-05-04 | 1971-04-26 | Mono-acetyl derivatives of antibiotic sf 837 and sf 837-a2 substances and production thereof |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3792035A (https=) |
| BE (1) | BE766710A (https=) |
| CA (1) | CA931142A (https=) |
| CH (1) | CH557348A (https=) |
| DE (1) | DE2121648C3 (https=) |
| FR (1) | FR2100626B1 (https=) |
| GB (1) | GB1325943A (https=) |
| NL (1) | NL165177C (https=) |
| SE (1) | SE393987B (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS563359B2 (https=) * | 1972-04-06 | 1981-01-24 | ||
| US3932383A (en) * | 1974-06-03 | 1976-01-13 | Abbott Laboratories | 9-Dihydroniddamycin A compounds and related 3-(O)-esters and the process for their preparation |
| US3970642A (en) * | 1974-06-03 | 1976-07-20 | Abbott Laboratories | Process for the conversion of niddamycin to leucomycin A1, leucomycin A3, carbomycin B and other antibiotics and related 3-O-esters |
| JPS5126887A (en) * | 1974-08-27 | 1976-03-05 | Meiji Seika Co | Koseibutsushitsu sff837m1 butsushitsuno 9*3**4* toriashirujudotaino seizoho |
| US3959256A (en) * | 1974-09-12 | 1976-05-25 | Meiji Seika Kaisha, Ltd. | 9-O-Alkanoyl-3"-O-alkanoyloxymethyl-SF-837 substance and the production thereof |
| US4980992A (en) * | 1989-10-13 | 1991-01-01 | Overhead Door Corporation | Revolving door assembly with foldable door wings |
| WO2000073317A1 (fr) * | 1999-06-01 | 2000-12-07 | Meiji Seika Kaisha, Ltd. | Derives de leucomycine modifiee en position 3 |
-
1971
- 1971-04-21 US US00135858A patent/US3792035A/en not_active Expired - Lifetime
- 1971-04-23 CA CA111201A patent/CA931142A/en not_active Expired
- 1971-04-26 GB GB1134071*[A patent/GB1325943A/en not_active Expired
- 1971-04-29 SE SE7105603A patent/SE393987B/xx unknown
- 1971-05-03 DE DE2121648A patent/DE2121648C3/de not_active Expired
- 1971-05-03 FR FR7115759A patent/FR2100626B1/fr not_active Expired
- 1971-05-04 BE BE766710A patent/BE766710A/xx not_active IP Right Cessation
- 1971-05-04 NL NL7106090.A patent/NL165177C/xx not_active IP Right Cessation
- 1971-05-04 CH CH659971A patent/CH557348A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2100626A1 (https=) | 1972-03-24 |
| SE393987B (sv) | 1977-05-31 |
| BE766710A (fr) | 1971-10-01 |
| NL165177C (nl) | 1981-03-16 |
| US3792035A (en) | 1974-02-12 |
| DE2121648C3 (de) | 1974-10-10 |
| DE2121648B2 (de) | 1974-03-07 |
| DE2121648A1 (de) | 1971-12-02 |
| FR2100626B1 (https=) | 1974-05-24 |
| CA931142A (en) | 1973-07-31 |
| NL7106090A (https=) | 1971-11-08 |
| NL165177B (nl) | 1980-10-15 |
| CH557348A (de) | 1974-12-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee | ||
| PE20 | Patent expired after termination of 20 years |