GB1324579A - N-substituted 3-aminoalkoxy-6-hydrazinopyridazines having antihypertensive activity and their preparation - Google Patents
N-substituted 3-aminoalkoxy-6-hydrazinopyridazines having antihypertensive activity and their preparationInfo
- Publication number
- GB1324579A GB1324579A GB5762071A GB5762071A GB1324579A GB 1324579 A GB1324579 A GB 1324579A GB 5762071 A GB5762071 A GB 5762071A GB 5762071 A GB5762071 A GB 5762071A GB 1324579 A GB1324579 A GB 1324579A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydrazinopyridazines
- antihypertensive activity
- hydroxyalkyl
- alkyl
- aminoalkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000003276 anti-hypertensive effect Effects 0.000 title abstract 2
- 125000006577 C1-C6 hydroxyalkyl group Chemical group 0.000 abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- YTRGNBTVTHPFJM-UHFFFAOYSA-N pyridazin-3-ylhydrazine Chemical class NNC1=CC=CN=N1 YTRGNBTVTHPFJM-UHFFFAOYSA-N 0.000 abstract 2
- VQAFMTSSCUETHA-UHFFFAOYSA-N 3,6-dibromopyridazine Chemical compound BrC1=CC=C(Br)N=N1 VQAFMTSSCUETHA-UHFFFAOYSA-N 0.000 abstract 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 238000010253 intravenous injection Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2523071 | 1971-05-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1324579A true GB1324579A (en) | 1973-07-25 |
Family
ID=11216066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5762071A Expired GB1324579A (en) | 1971-05-29 | 1971-12-10 | N-substituted 3-aminoalkoxy-6-hydrazinopyridazines having antihypertensive activity and their preparation |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3891641A (enExample) |
| JP (1) | JPS5117553B1 (enExample) |
| BE (1) | BE778206A (enExample) |
| DE (1) | DE2164618A1 (enExample) |
| FR (1) | FR2139798B1 (enExample) |
| GB (1) | GB1324579A (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1555751A (en) * | 1977-02-02 | 1979-11-14 | Farmaceutici Italia | Ergoline deritatives |
| JPS5827272U (ja) * | 1981-08-19 | 1983-02-22 | 三菱電機株式会社 | エレベ−タ用巻上機 |
| US4599333A (en) * | 1982-06-14 | 1986-07-08 | Teikoku Hormone Mfg. Co., Ltd. | Hydrazinopyridazine compound, process for production thereof, and use thereof as medicament |
| US5082939A (en) * | 1987-01-08 | 1992-01-21 | I.S.F. Societa Per Azioni | Pyridazine derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2858311A (en) * | 1955-08-31 | 1958-10-28 | Sterling Drug Inc | 3, 6-bis(tertiary-amino-aliphatic) substituted pyridazines, and their preparation |
| US3598822A (en) * | 1969-01-21 | 1971-08-10 | Sandoz Ag | 3-substituted amino-6-hydrazino pyridazines |
| US3579517A (en) * | 1969-09-22 | 1971-05-18 | Sandoz Ag | Secondaryamino pyridazines |
-
1971
- 1971-12-10 GB GB5762071A patent/GB1324579A/en not_active Expired
- 1971-12-16 JP JP46101527A patent/JPS5117553B1/ja active Pending
- 1971-12-24 DE DE19712164618 patent/DE2164618A1/de active Pending
- 1971-12-27 FR FR7146756A patent/FR2139798B1/fr not_active Expired
-
1972
- 1972-01-17 US US218531A patent/US3891641A/en not_active Expired - Lifetime
- 1972-01-18 BE BE778206A patent/BE778206A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE778206A (fr) | 1972-05-16 |
| FR2139798A1 (enExample) | 1973-01-12 |
| FR2139798B1 (enExample) | 1975-12-26 |
| JPS5117553B1 (enExample) | 1976-06-03 |
| DE2164618A1 (de) | 1972-12-14 |
| US3891641A (en) | 1975-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |