GB1320031A - Process for the manufacture of imidazole derivatives - Google Patents

Process for the manufacture of imidazole derivatives

Info

Publication number
GB1320031A
GB1320031A GB3079570A GB3079570A GB1320031A GB 1320031 A GB1320031 A GB 1320031A GB 3079570 A GB3079570 A GB 3079570A GB 3079570 A GB3079570 A GB 3079570A GB 1320031 A GB1320031 A GB 1320031A
Authority
GB
United Kingdom
Prior art keywords
reacting
formula
prepared
compound
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3079570A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1320031A publication Critical patent/GB1320031A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB3079570A 1969-06-26 1970-06-25 Process for the manufacture of imidazole derivatives Expired GB1320031A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83694269A 1969-06-26 1969-06-26

Publications (1)

Publication Number Publication Date
GB1320031A true GB1320031A (en) 1973-06-13

Family

ID=25273099

Family Applications (2)

Application Number Title Priority Date Filing Date
GB3079570A Expired GB1320031A (en) 1969-06-26 1970-06-25 Process for the manufacture of imidazole derivatives
GB5938072A Expired GB1320032A (en) 1969-06-26 1970-06-25 Imidazole derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB5938072A Expired GB1320032A (en) 1969-06-26 1970-06-25 Imidazole derivatives

Country Status (6)

Country Link
US (1) US3652579A (https=)
BR (1) BR7019965D0 (https=)
ES (1) ES381138A1 (https=)
GB (2) GB1320031A (https=)
IE (1) IE34340B1 (https=)
PL (1) PL80719B1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7017486A (https=) * 1969-12-15 1971-06-17
BE793407A (fr) * 1971-12-28 1973-06-28 Hoechst Ag Imidazolyl - (2) -carbinols ayant une activite hypolipidemique et leur procede de preparation
US4007200A (en) * 1974-05-06 1977-02-08 American Cyanamid Company Imidazolines and a method for their production
GB1480192A (en) * 1975-01-15 1977-07-20 Lepetit Spa 1-methyl-2-nitro-imidazole-5-methanol derivatives
GB1526451A (en) * 1976-01-27 1978-09-27 Lepetit Spa Alpha,alpha,1-trimethyl-2-nitroimidazole-5-methanol derivatives
FR2717474B1 (fr) * 1994-03-15 1996-06-21 Hoechst France Procédé de préparation d'acétals du formyl-2 imidazole.
ZA200507752B (en) * 2003-03-28 2007-01-31 Threshold Pharmaceuticals Inc Compositions and methods for treating cancer
MY140748A (en) 2004-12-06 2010-01-15 Astrazeneca Ab Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
EP1896040B1 (en) 2005-06-29 2012-08-01 Threshold Pharmaceuticals, Inc. Phosphoramidate alkylator prodrugs
ES2884044T3 (es) * 2006-12-26 2021-12-10 Immunogenesis Inc Profármaco alquilante de fosforamidato para el tratamiento del cáncer
US20090118031A1 (en) * 2007-11-01 2009-05-07 Qualizza Gregory K Shaft Structure with Configurable Bending Profile

Also Published As

Publication number Publication date
ES381138A1 (es) 1972-11-16
GB1320032A (en) 1973-06-13
US3652579A (en) 1972-03-28
IE34340L (en) 1970-12-26
PL80719B1 (https=) 1975-08-30
IE34340B1 (en) 1975-04-16
BR7019965D0 (pt) 1973-03-07

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee