GB1317379A - Benzimidazoles their preparation and pharmaceutical compositions containing them - Google Patents

Benzimidazoles their preparation and pharmaceutical compositions containing them

Info

Publication number
GB1317379A
GB1317379A GB2274471A GB2274471A GB1317379A GB 1317379 A GB1317379 A GB 1317379A GB 2274471 A GB2274471 A GB 2274471A GB 2274471 A GB2274471 A GB 2274471A GB 1317379 A GB1317379 A GB 1317379A
Authority
GB
United Kingdom
Prior art keywords
alkyl
alkoxy
compounds
reacting
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2274471A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1317379A publication Critical patent/GB1317379A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB2274471A 1970-03-05 1971-04-19 Benzimidazoles their preparation and pharmaceutical compositions containing them Expired GB1317379A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1695770A 1970-03-05 1970-03-05
US14934271A 1971-06-02 1971-06-02

Publications (1)

Publication Number Publication Date
GB1317379A true GB1317379A (en) 1973-05-16

Family

ID=26689269

Family Applications (2)

Application Number Title Priority Date Filing Date
GB2274471A Expired GB1317379A (en) 1970-03-05 1971-04-19 Benzimidazoles their preparation and pharmaceutical compositions containing them
GB2273971A Expired GB1328321A (en) 1970-03-05 1971-04-19 2-heteroaryl benzimidazole derivatives useful as anthelmintics

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB2273971A Expired GB1328321A (en) 1970-03-05 1971-04-19 2-heteroaryl benzimidazole derivatives useful as anthelmintics

Country Status (9)

Country Link
US (2) US3646049A (https=)
AT (1) AT310738B (https=)
BE (1) BE763781R (https=)
CA (1) CA967962A (https=)
CH (1) CH566344A5 (https=)
DE (1) DE2110396A1 (https=)
FR (1) FR2085671B1 (https=)
GB (2) GB1317379A (https=)
NL (2) NL7102895A (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1221596A (en) * 1967-12-06 1971-02-03 Merck & Co Inc Benzimidazole derivatives
US3922262A (en) * 1971-04-28 1975-11-25 Nippon Kayaku Kk N-Substituted derivatives of bleomycins
US3956488A (en) * 1973-09-27 1976-05-11 Merck & Co., Inc. Compositions and methods for the treatment of helminthiasis
US4405621A (en) * 1974-02-07 1983-09-20 Smith Kline & French Laboratories Limited Heterocyclic thioureas, isothioureas, guanidines and nitromethylene-amidines
GB1493931A (en) * 1974-02-07 1977-11-30 Smith Kline French Lab Guanidines isothioureas and thioureas
US4649149A (en) * 1980-05-22 1987-03-10 Ciba-Geigy Corporation Process for the manufacture of novel benzazole derivatives, pharmaceutical preparations containing these derivatives, and their use
MA19290A1 (fr) * 1980-05-22 1982-04-01 Ciba Geigy Ag Derives du benzole,leur preparaton et leur utilisations therapeutiques .
PT89098B (pt) * 1987-11-30 1993-03-31 Beecham Group Plc Processo para a preparacao de derivados de guanina
US5247085A (en) * 1987-11-30 1993-09-21 Beecham Group P.L.C. Antiviral purine compounds
US5693515A (en) * 1995-04-28 1997-12-02 Arris Pharmaceutical Corporation Metal complexed serine protease inhibitors
US6255091B1 (en) * 1995-04-28 2001-07-03 Axys Pharmaceuticals, Inc. Potentiating metal mediated serine protease inhibitors with cobalt or zinc ions
WO2001000214A1 (en) 1999-06-30 2001-01-04 Merck & Co., Inc. Src kinase inhibitor compounds
AU5636900A (en) 1999-06-30 2001-01-31 Merck & Co., Inc. Src kinase inhibitor compounds
JP2003503351A (ja) 1999-06-30 2003-01-28 メルク エンド カムパニー インコーポレーテッド Ｓｒｃキナーゼ阻害化合物
US7405235B2 (en) * 2001-05-04 2008-07-29 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
WO2004041209A2 (en) * 2002-11-01 2004-05-21 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
EP1581217A4 (en) * 2002-11-01 2007-07-11 Merck & Co Inc CARBONYLAMINO-BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF ANDROGENIC RECEPTORS
EP1742637A4 (en) 2004-04-23 2011-06-08 Paratek Pharm Innc TRANSCRIPTION FACTOR MODULATION COMPOUNDS AND METHODS OF USE
CA2656157A1 (en) * 2006-06-23 2008-10-30 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
CA2681813A1 (en) * 2007-03-27 2009-01-08 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
US20090191138A1 (en) * 2008-01-30 2009-07-30 Mediquest Therapeutics, Inc. Novel topical formulations for improving the appearance of nails
EP2732819B1 (en) 2008-02-07 2019-10-16 Massachusetts Eye & Ear Infirmary Compounds that enhance Atoh-1 expression
US20110059962A1 (en) * 2009-04-22 2011-03-10 Alekshun Michael N Transcription factor modulating compounds and methods of use thereof
WO2021236717A1 (en) * 2020-05-20 2021-11-25 Senda Biosciences, Inc. Fused imidazole derivatives as ahr antagonists

Also Published As

Publication number Publication date
BE763781R (fr) 1971-09-06
NL7102895A (https=) 1971-09-07
FR2085671A1 (https=) 1971-12-31
GB1328321A (en) 1973-08-30
AT310738B (de) 1973-10-10
US3743738A (en) 1973-07-03
CH566344A5 (https=) 1975-09-15
DE2110396A1 (de) 1971-09-23
US3646049A (en) 1972-02-29
CA967962A (en) 1975-05-20
FR2085671B1 (https=) 1975-04-18
NL7102896A (https=) 1971-09-07

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee