GB1317256A - 2,4-disubstituted thiazole derivatives - Google Patents

2,4-disubstituted thiazole derivatives

Info

Publication number
GB1317256A
GB1317256A GB3559369A GB1317256DA GB1317256A GB 1317256 A GB1317256 A GB 1317256A GB 3559369 A GB3559369 A GB 3559369A GB 1317256D A GB1317256D A GB 1317256DA GB 1317256 A GB1317256 A GB 1317256A
Authority
GB
United Kingdom
Prior art keywords
alkyl
formula
atoms
compound
ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3559369A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of GB1317256A publication Critical patent/GB1317256A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1317256 Nitrofuran and nitrothiophene derivatives LILLY INDUSTRIES Ltd 6 July 1970 [15 July 1969 20 April 1970] 35593/69 and 18801/70 Heading C2C Novel compounds of Formula I (in which Y is O or S, n is 0 or 1, R is H or C 1-6 alkyl, and each of R<SP>1</SP> and R<SP>11</SP> is H, C 1-6 alkyl, hydroxy-C 1-6 alkyl or C 1-6 alkoxy-C 1-6 alkyl, or R<SP>1</SP> and R<SP>11</SP>, together with the adjacent nitrogen atom, form a heterocyclic ring having 5 to 7 ring atoms, up to 2 of which are hetero atoms selected from N, O and S atoms, and the remainder of which are C atoms, said ring being optionally substituted by one or more C 1-6 alkyl, hydroxy-C 1-6 alkyl or OH substitutes, and any sulphur atom being optionally oxidized) are prepared by reacting a compound of Formula II with a compound of formula H 2 N.NR<SP>1</SP>R<SP>11</SP>. Pharmaceutical compositions having antitrypanosomal activity, for oral or parenteral administration, comprise a compound of Formula I together with a pharmaceutical carrier.
GB3559369A 1969-07-15 1969-07-15 2,4-disubstituted thiazole derivatives Expired GB1317256A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3559369 1969-07-15

Publications (1)

Publication Number Publication Date
GB1317256A true GB1317256A (en) 1973-05-16

Family

ID=10379457

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3559369A Expired GB1317256A (en) 1969-07-15 1969-07-15 2,4-disubstituted thiazole derivatives

Country Status (3)

Country Link
BR (1) BR6915440D0 (en)
GB (1) GB1317256A (en)
ZA (1) ZA704654B (en)

Also Published As

Publication number Publication date
BR6915440D0 (en) 1973-01-04
ZA704654B (en) 1971-08-25

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees