GB1313539A - Sulphonyl-ureas - Google Patents

Sulphonyl-ureas

Info

Publication number
GB1313539A
GB1313539A GB3172270A GB3172270A GB1313539A GB 1313539 A GB1313539 A GB 1313539A GB 3172270 A GB3172270 A GB 3172270A GB 3172270 A GB3172270 A GB 3172270A GB 1313539 A GB1313539 A GB 1313539A
Authority
GB
United Kingdom
Prior art keywords
optionally substituted
compounds
june
alkyl
sulphonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3172270A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691933388 external-priority patent/DE1933388A1/en
Priority claimed from DE19702027436 external-priority patent/DE2027436A1/en
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of GB1313539A publication Critical patent/GB1313539A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1313539 Sulphonyl-ureas DR KARL THOMAE GmbH 30 June 1970 [1 July 1969 4 June 1970] 31722/70 Heading C2C Novel compounds I (including salts thereof) where R 1 is C 1-4 alkyl, phenyl optionally substituted by C 1-3 alkoxy, Me or CF 3 , by one or two halogens or by 2-MeO and 5-Cl, or is biphenyl, α - naphthyl, 1,2,3,4 - tetrahydronaphthyl-(1), indanyl-(1) or benzoyl, R 2 is nbutyl, C 5-8 cycloalkyl optionally substituted by Me or Et, or is adamantyl-(1), A is a C 1-5 bivalent aliphatic hydrocarbon group optionally substituted by Ph or is a direct bond and n is 1 or 2, are made by standard methods utilizing compounds II and compounds VI (X signifies NH 2 or NHCO 2 alkyl; salts of II are also exemplified); N,N-bis-carbethoxy-2- (3 - phenylpropionyl) - 1,2,3,4 - tetrahydroisoquinoline-7-sulphonamide is also described. Pharmaceutical preparations showing, in particular, hypoglycaemic activity contain (I) as active ingredient; administration may be orally, rectally or parenterally.
GB3172270A 1969-07-01 1970-06-30 Sulphonyl-ureas Expired GB1313539A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19691933388 DE1933388A1 (en) 1969-07-01 1969-07-01 New sulfonylureas and processes for their preparation
DE19702027436 DE2027436A1 (en) 1970-06-04 1970-06-04 Sulphenylurea cpds, hypoglycaemics

Publications (1)

Publication Number Publication Date
GB1313539A true GB1313539A (en) 1973-04-11

Family

ID=25757577

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3172270A Expired GB1313539A (en) 1969-07-01 1970-06-30 Sulphonyl-ureas

Country Status (16)

Country Link
AT (1) AT301568B (en)
BE (1) BE752760A (en)
BG (1) BG18181A1 (en)
CH (1) CH536842A (en)
DK (1) DK127928B (en)
ES (2) ES381248A1 (en)
FI (1) FI49828C (en)
FR (1) FR2059465B1 (en)
GB (1) GB1313539A (en)
IE (1) IE34359B1 (en)
IL (1) IL34820A (en)
NL (1) NL7009704A (en)
NO (1) NO132094C (en)
PL (1) PL81112B1 (en)
RO (1) RO56857A (en)
SE (1) SE357745B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001087834A1 (en) * 2000-05-16 2001-11-22 Takeda Chemical Industries, Ltd. Melanin-concentrating hormone antagonist

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001087834A1 (en) * 2000-05-16 2001-11-22 Takeda Chemical Industries, Ltd. Melanin-concentrating hormone antagonist
US7229986B2 (en) 2000-05-16 2007-06-12 Takeda Pharmaceutical Company Ltd. Melanin-concentrating hormone antagonist

Also Published As

Publication number Publication date
BG18181A1 (en) 1974-09-02
PL81112B1 (en) 1975-08-30
FR2059465B1 (en) 1974-03-22
IL34820A (en) 1973-08-29
SE357745B (en) 1973-07-09
NO132094B (en) 1975-06-09
DK127928B (en) 1974-02-04
CH536842A (en) 1973-05-15
NL7009704A (en) 1971-01-05
FI49828B (en) 1975-06-30
RO56857A (en) 1974-12-15
BE752760A (en) 1970-12-30
NO132094C (en) 1975-09-17
IE34359B1 (en) 1975-04-16
ES381248A1 (en) 1972-11-01
IL34820A0 (en) 1970-09-17
FR2059465A1 (en) 1971-06-04
AT301568B (en) 1972-09-11
IE34359L (en) 1971-01-01
ES393416A1 (en) 1974-06-01
FI49828C (en) 1975-10-10

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees