GB1305007A - - Google Patents
Info
- Publication number
- GB1305007A GB1305007A GB2079771A GB2079771A GB1305007A GB 1305007 A GB1305007 A GB 1305007A GB 2079771 A GB2079771 A GB 2079771A GB 2079771 A GB2079771 A GB 2079771A GB 1305007 A GB1305007 A GB 1305007A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyrazine
- acetamidobenzenesulphonamido
- aminobenzenesulphonamido
- sulpha
- dichloropyrazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- MLCNOCRGSBCAGH-UHFFFAOYSA-N 2,3-dichloropyrazine Chemical compound ClC1=NC=CN=C1Cl MLCNOCRGSBCAGH-UHFFFAOYSA-N 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- PKOFBDHYTMYVGJ-UHFFFAOYSA-N n-(4-sulfamoylphenyl)acetamide Chemical compound CC(=O)NC1=CC=C(S(N)(=O)=O)C=C1 PKOFBDHYTMYVGJ-UHFFFAOYSA-N 0.000 abstract 1
- OPQHCQPFIZMSPX-UHFFFAOYSA-N n-[4-[(3-chloropyrazin-2-yl)sulfamoyl]phenyl]acetamide Chemical compound C1=CC(NC(=O)C)=CC=C1S(=O)(=O)NC1=NC=CN=C1Cl OPQHCQPFIZMSPX-UHFFFAOYSA-N 0.000 abstract 1
- DDBREPKUVSBGFI-UHFFFAOYSA-N phenobarbital Chemical compound C=1C=CC=CC=1C1(CC)C(=O)NC(=O)NC1=O DDBREPKUVSBGFI-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- KXRZBTAEDBELFD-UHFFFAOYSA-N sulfamethopyrazine Chemical compound COC1=NC=CN=C1NS(=O)(=O)C1=CC=C(N)C=C1 KXRZBTAEDBELFD-UHFFFAOYSA-N 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
- C07D241/22—Benzenesulfonamido pyrazines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1305007 Sulpha - pyrazines CHINOIN GYOGYSZER - ES. VEGYESZETI TERMEKEK GYARA RT 19 April 1971 [30 Jan 1970] 20797/71 Heading C2C The invention comprises a process for making therapeutic 2 - (p-aminobenzenesulphonamido ) - 3-methoxy-pyrazine and salts thereof by reacting novel 2-(p-acetamidobenzenesulphonamido)-3- chloro-pyrazine (made by interacting 2,3-dichloropyrazine and p-acetamido-benzene-sulphonamide) with methanol containing an alkali metal hydroxide and if desired acidifying to produce the free compound.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUBO001216 | 1970-01-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1305007A true GB1305007A (en) | 1973-01-31 |
Family
ID=10993692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2079771A Expired GB1305007A (en) | 1970-01-30 | 1971-04-19 |
Country Status (5)
| Country | Link |
|---|---|
| AT (1) | AT302312B (en) |
| CH (1) | CH548402A (en) |
| ES (1) | ES387761A1 (en) |
| GB (1) | GB1305007A (en) |
| SE (1) | SE381465B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT7967132A0 (en) * | 1979-01-22 | 1979-01-22 | Marxer Spa | PROCEDURE FOR THE SYNTHESIS OF 2BENZENESULFONAMIDO 3METHOXYPYRAZINE |
-
1971
- 1971-01-29 CH CH132371A patent/CH548402A/en not_active IP Right Cessation
- 1971-01-29 ES ES387761A patent/ES387761A1/en not_active Expired
- 1971-01-29 AT AT73471A patent/AT302312B/en not_active IP Right Cessation
- 1971-01-29 SE SE7101122A patent/SE381465B/en unknown
- 1971-04-19 GB GB2079771A patent/GB1305007A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH548402A (en) | 1974-04-30 |
| SE381465B (en) | 1975-12-08 |
| AT302312B (en) | 1972-10-10 |
| ES387761A1 (en) | 1973-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 429A | Application made for amendment of specification (sect. 29/1949) | ||
| 429H | Application (made) for amendment of specification now open to opposition (sect. 29/1949) | ||
| 435 | Patent endorsed 'licences of right' on the date specified (sect. 35/1949) | ||
| 429D | Case decided by the comptroller ** specification amended (sect. 29/1949) | ||
| PCNP | Patent ceased through non-payment of renewal fee |