GB1301795A - - Google Patents
Info
- Publication number
- GB1301795A GB1301795A GB4358771A GB4358771A GB1301795A GB 1301795 A GB1301795 A GB 1301795A GB 4358771 A GB4358771 A GB 4358771A GB 4358771 A GB4358771 A GB 4358771A GB 1301795 A GB1301795 A GB 1301795A
- Authority
- GB
- United Kingdom
- Prior art keywords
- antigens
- bacilli
- esterification
- purifying
- purified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000427 antigen Substances 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 244000052616 bacterial pathogen Species 0.000 abstract 4
- 229960005486 vaccine Drugs 0.000 abstract 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 230000032050 esterification Effects 0.000 abstract 3
- 238000005886 esterification reaction Methods 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 230000024932 T cell mediated immunity Effects 0.000 abstract 2
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 230000003053 immunization Effects 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- 239000000725 suspension Substances 0.000 abstract 2
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 abstract 1
- 108090000317 Chymotrypsin Proteins 0.000 abstract 1
- YXHKONLOYHBTNS-UHFFFAOYSA-N Diazomethane Chemical compound C=[N+]=[N-] YXHKONLOYHBTNS-UHFFFAOYSA-N 0.000 abstract 1
- 108090000631 Trypsin Proteins 0.000 abstract 1
- 102000004142 Trypsin Human genes 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 abstract 1
- 239000001166 ammonium sulphate Substances 0.000 abstract 1
- 235000011130 ammonium sulphate Nutrition 0.000 abstract 1
- 230000002365 anti-tubercular Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 229960002376 chymotrypsin Drugs 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000012153 distilled water Substances 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008363 phosphate buffer Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- 239000012588 trypsin Substances 0.000 abstract 1
- 229960002109 tuberculosis vaccine Drugs 0.000 abstract 1
- 239000007762 w/o emulsion Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10572771A | 1971-01-11 | 1971-01-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1301795A true GB1301795A (enExample) | 1973-01-04 |
Family
ID=22307466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4358771A Expired GB1301795A (enExample) | 1971-01-11 | 1971-09-17 |
Country Status (3)
| Country | Link |
|---|---|
| DE (1) | DE2139610A1 (enExample) |
| FR (1) | FR2121499B1 (enExample) |
| GB (1) | GB1301795A (enExample) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE417443C (de) * | 1923-06-09 | 1925-08-12 | Hoechst Ag | Verfahren zur Darstellung von wasser-, alkohol- und oelloeslichen Tuberkulinpraeparaten |
-
1971
- 1971-08-04 DE DE19712139610 patent/DE2139610A1/de active Pending
- 1971-09-17 GB GB4358771A patent/GB1301795A/en not_active Expired
- 1971-10-12 FR FR7137754A patent/FR2121499B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2139610A1 (de) | 1972-07-27 |
| FR2121499A1 (enExample) | 1972-08-25 |
| FR2121499B1 (enExample) | 1975-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |