GB1293702A - 4,5-diphenyloxazole derivatives - Google Patents
4,5-diphenyloxazole derivativesInfo
- Publication number
- GB1293702A GB1293702A GB22899/71A GB2289971A GB1293702A GB 1293702 A GB1293702 A GB 1293702A GB 22899/71 A GB22899/71 A GB 22899/71A GB 2289971 A GB2289971 A GB 2289971A GB 1293702 A GB1293702 A GB 1293702A
- Authority
- GB
- United Kingdom
- Prior art keywords
- diphenyl
- alkyl
- phenyl
- amino
- chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ODKHOKLXMBWVOQ-UHFFFAOYSA-N 4,5-diphenyl-1,3-oxazole Chemical class O1C=NC(C=2C=CC=CC=2)=C1C1=CC=CC=C1 ODKHOKLXMBWVOQ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- VUPXKQHLZATXTR-UHFFFAOYSA-N 2,4-diphenyl-1,3-oxazole Chemical class C=1OC(C=2C=CC=CC=2)=NC=1C1=CC=CC=C1 VUPXKQHLZATXTR-UHFFFAOYSA-N 0.000 abstract 1
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- LZQSVRYXONEYIT-UHFFFAOYSA-N 2-amino-1,2-diphenylethanone;hydrochloride Chemical compound [Cl-].C=1C=CC=CC=1C([NH3+])C(=O)C1=CC=CC=C1 LZQSVRYXONEYIT-UHFFFAOYSA-N 0.000 abstract 1
- MEJOWRJWDWAODC-UHFFFAOYSA-N 4,5-diphenyl-1,3-oxazole-2-carboxylic acid Chemical compound O1C(C(=O)O)=NC(C=2C=CC=CC=2)=C1C1=CC=CC=C1 MEJOWRJWDWAODC-UHFFFAOYSA-N 0.000 abstract 1
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Natural products CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000000994 depressogenic effect Effects 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- RRRQDMLSVFUTTC-UHFFFAOYSA-N ethyl 2-(4,5-diphenyl-1,3-oxazol-2-yl)acetate Chemical compound O1C(CC(=O)OCC)=NC(C=2C=CC=CC=2)=C1C1=CC=CC=C1 RRRQDMLSVFUTTC-UHFFFAOYSA-N 0.000 abstract 1
- KWFADUNOPOSMIJ-UHFFFAOYSA-N ethyl 3-chloro-3-oxopropanoate Chemical compound CCOC(=O)CC(Cl)=O KWFADUNOPOSMIJ-UHFFFAOYSA-N 0.000 abstract 1
- JLRPAKXWJNHYIU-UHFFFAOYSA-N ethyl 3-oxo-3-[(2-oxo-1,2-diphenylethyl)amino]propanoate Chemical compound C1(=CC=CC=C1)C(C(=O)C1=CC=CC=C1)NC(CC(=O)OCC)=O JLRPAKXWJNHYIU-UHFFFAOYSA-N 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- -1 having analgesic Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000000717 hydrazino group Chemical group [H]N([*])N([H])[H] 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000004702 methyl esters Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- OFPXSFXSNFPTHF-UHFFFAOYSA-N oxaprozin Chemical compound O1C(CCC(=O)O)=NC(C=2C=CC=CC=2)=C1C1=CC=CC=C1 OFPXSFXSNFPTHF-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21550/70A IT1043805B (it) | 1970-03-05 | 1970-03-05 | Ammidi e idrazidi di acidi carbos silici derivanti dal 4,5,difenilossazolo e processo per la loro preparazione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1293702A true GB1293702A (en) | 1972-10-25 |
Family
ID=11183453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB22899/71A Expired GB1293702A (en) | 1970-03-05 | 1971-04-19 | 4,5-diphenyloxazole derivatives |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3869455A (cg-RX-API-DMAC10.html) |
| JP (1) | JPS504663B1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA949580A (cg-RX-API-DMAC10.html) |
| CH (1) | CH555846A (cg-RX-API-DMAC10.html) |
| DE (1) | DE2110363A1 (cg-RX-API-DMAC10.html) |
| FR (1) | FR2085675B1 (cg-RX-API-DMAC10.html) |
| GB (1) | GB1293702A (cg-RX-API-DMAC10.html) |
| IT (1) | IT1043805B (cg-RX-API-DMAC10.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5262540A (en) * | 1989-12-20 | 1993-11-16 | Bristol-Myers Squibb Company | [2(4,5-diaryl-2 oxazoyl substituted phenoxy alkanoic acid and esters |
| FR2677477B1 (fr) * | 1991-06-06 | 1993-08-20 | Bellon Labor Sa Roger | Nouveaux derives de l'oxazole leur preparation, leur utilisation et les compositions pharmaceutiques qui les contiennent. |
| FR2677355B1 (fr) * | 1991-06-06 | 1993-08-20 | Bellon Labor Sa Roger | Nouveaux derives de l'oxazole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| RU2005135927A (ru) * | 2003-04-21 | 2006-05-10 | Дайити Фармасьютикал Ко., Лтд. (JP) | Пятичленное гетероциклическое производное |
| FR2866340B1 (fr) * | 2004-02-13 | 2006-11-24 | Sanofi Synthelabo | Derives d'oxazole, leur preparation et leur utilisation en therapeutique. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2166118A (en) * | 1936-10-03 | 1939-07-18 | Du Pont | Insecticidal compositions containing heterocyclic amides |
| US3401120A (en) * | 1965-10-23 | 1968-09-10 | Gaf Corp | Corrosion inhibitors |
| US3578671A (en) * | 1967-11-06 | 1971-05-11 | Wyeth John & Brother Ltd | Oxazoles |
| IT1053674B (it) * | 1968-01-31 | 1981-10-10 | Istituto Farmacobiologico Sero | N amidino carbossiamidi ossazoliche ad azione natriuretica |
-
1970
- 1970-03-05 IT IT21550/70A patent/IT1043805B/it active
-
1971
- 1971-02-26 CH CH283971A patent/CH555846A/it not_active IP Right Cessation
- 1971-03-01 US US119832A patent/US3869455A/en not_active Expired - Lifetime
- 1971-03-04 CA CA106,905A patent/CA949580A/en not_active Expired
- 1971-03-04 DE DE19712110363 patent/DE2110363A1/de active Pending
- 1971-03-05 FR FR7107751A patent/FR2085675B1/fr not_active Expired
- 1971-03-05 JP JP46011584A patent/JPS504663B1/ja active Pending
- 1971-04-19 GB GB22899/71A patent/GB1293702A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2110363A1 (de) | 1971-09-16 |
| FR2085675B1 (cg-RX-API-DMAC10.html) | 1974-04-12 |
| FR2085675A1 (cg-RX-API-DMAC10.html) | 1971-12-31 |
| CA949580A (en) | 1974-06-18 |
| CH555846A (it) | 1974-11-15 |
| US3869455A (en) | 1975-03-04 |
| JPS504663B1 (cg-RX-API-DMAC10.html) | 1975-02-22 |
| IT1043805B (it) | 1980-02-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |