GB1291657A - Indole derivatives - Google Patents

Indole derivatives

Info

Publication number
GB1291657A
GB1291657A GB57292/70D GB5729270D GB1291657A GB 1291657 A GB1291657 A GB 1291657A GB 57292/70 D GB57292/70 D GB 57292/70D GB 5729270 D GB5729270 D GB 5729270D GB 1291657 A GB1291657 A GB 1291657A
Authority
GB
United Kingdom
Prior art keywords
alkyl
halo
substituted
alkoxy
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB57292/70D
Other languages
English (en)
Inventor
C Ronney
C Gleason
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Merck Sharp & Dohme (I.A.) Corp
Original Assignee
Merck Sharp and Dohme Ltd
Merck Sharp & Dohme (I.A.) Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd, Merck Sharp & Dohme (I.A.) Corp filed Critical Merck Sharp and Dohme Ltd
Publication of GB1291657A publication Critical patent/GB1291657A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/12—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom
    • C07C245/14—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB57292/70D 1970-02-03 1970-12-02 Indole derivatives Expired GB1291657A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA73875 1970-02-03

Publications (1)

Publication Number Publication Date
GB1291657A true GB1291657A (en) 1972-10-04

Family

ID=4086280

Family Applications (1)

Application Number Title Priority Date Filing Date
GB57292/70D Expired GB1291657A (en) 1970-02-03 1970-12-02 Indole derivatives

Country Status (14)

Country Link
US (1) US3758500A (enExample)
JP (1) JPS4829224B1 (enExample)
BE (1) BE759743A (enExample)
CA (1) CA903210A (enExample)
DE (1) DE2062017A1 (enExample)
DK (1) DK129993B (enExample)
ES (1) ES386460A1 (enExample)
FR (1) FR2081481B1 (enExample)
GB (1) GB1291657A (enExample)
HU (1) HU162286B (enExample)
IL (1) IL35771A (enExample)
NL (1) NL7017488A (enExample)
SE (1) SE372266B (enExample)
ZA (1) ZA707949B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7119214B2 (en) * 2004-04-13 2006-10-10 Cephalon France Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives
US12168653B2 (en) 2018-03-02 2024-12-17 Inflazome Limited Sulfonamide derivates as NLRP3 inhibitors
US20220227707A1 (en) * 2019-01-22 2022-07-21 Novartis Ag Compounds and compositions for treating conditions associated with nlrp activity
WO2020249669A1 (en) * 2019-06-12 2020-12-17 NodThera Limited Sulfonamide derivatives and uses thereof

Also Published As

Publication number Publication date
DK129993B (da) 1974-12-09
IL35771A0 (en) 1971-02-25
CA903210A (en) 1972-06-20
DK129993C (enExample) 1975-05-20
ZA707949B (en) 1972-07-26
FR2081481A1 (enExample) 1971-12-03
JPS4829224B1 (enExample) 1973-09-08
US3758500A (en) 1973-09-11
BE759743A (fr) 1971-06-02
IL35771A (en) 1974-12-31
HU162286B (enExample) 1973-01-29
SE372266B (enExample) 1974-12-16
DE2062017A1 (de) 1971-08-12
NL7017488A (enExample) 1971-08-05
ES386460A1 (es) 1973-04-01
FR2081481B1 (enExample) 1974-03-22

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees