GB1289209A - - Google Patents
Info
- Publication number
- GB1289209A GB1289209A GB1289209DA GB1289209A GB 1289209 A GB1289209 A GB 1289209A GB 1289209D A GB1289209D A GB 1289209DA GB 1289209 A GB1289209 A GB 1289209A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- group
- carbon atoms
- specified above
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 3
- LLBZPESJRQGYMB-UHFFFAOYSA-N 4-one Natural products O1C(C(=O)CC)CC(C)C11C2(C)CCC(C3(C)C(C(C)(CO)C(OC4C(C(O)C(O)C(COC5C(C(O)C(O)CO5)OC5C(C(OC6C(C(O)C(O)C(CO)O6)O)C(O)C(CO)O5)OC5C(C(O)C(O)C(C)O5)O)O4)O)CC3)CC3)=C3C2(C)CC1 LLBZPESJRQGYMB-UHFFFAOYSA-N 0.000 abstract 2
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- ATTZFSUZZUNHBP-UHFFFAOYSA-N Piperonyl sulfoxide Chemical compound CCCCCCCCS(=O)C(C)CC1=CC=C2OCOC2=C1 ATTZFSUZZUNHBP-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 239000000376 reactant Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- HRJYGQAACVZSEO-UHFFFAOYSA-N 2-chloro-9h-thioxanthene Chemical compound C1=CC=C2CC3=CC(Cl)=CC=C3SC2=C1 HRJYGQAACVZSEO-UHFFFAOYSA-N 0.000 abstract 1
- 125000001731 2-cyanoethyl group Chemical group [H]C([H])(*)C([H])([H])C#N 0.000 abstract 1
- HXPVRJJPTDOMFH-UHFFFAOYSA-N 3-[2-chloro-9-(2-cyanoethyl)thioxanthen-9-yl]propanenitrile Chemical compound C(#N)CCC1(C2=CC=CC=C2SC=2C=CC(=CC12)Cl)CCC#N HXPVRJJPTDOMFH-UHFFFAOYSA-N 0.000 abstract 1
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical group C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- -1 carboxylic acid methylester Chemical class 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 150000002081 enamines Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002443 hydroxylamines Chemical class 0.000 abstract 1
- 238000003402 intramolecular cyclocondensation reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- OJURWUUOVGOHJZ-UHFFFAOYSA-N methyl 2-[(2-acetyloxyphenyl)methyl-[2-[(2-acetyloxyphenyl)methyl-(2-methoxy-2-oxoethyl)amino]ethyl]amino]acetate Chemical compound C=1C=CC=C(OC(C)=O)C=1CN(CC(=O)OC)CCN(CC(=O)OC)CC1=CC=CC=C1OC(C)=O OJURWUUOVGOHJZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000002902 organometallic compounds Chemical class 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19691957490 DE1957490A1 (de) | 1969-11-15 | 1969-11-15 | 4-Amino-spiro [cyclohexan-1,9'-thioxanthen]-Verbindungen sowie Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1289209A true GB1289209A (enrdf_load_stackoverflow) | 1972-09-13 |
Family
ID=5751176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1289209D Expired GB1289209A (enrdf_load_stackoverflow) | 1969-11-15 | 1970-10-08 |
Country Status (16)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1434486A (en) * | 1974-02-04 | 1976-05-05 | Ici Ltd | Thioxanthene derivatives |
| GB1447583A (en) * | 1974-02-04 | 1976-08-25 | Ici Ltd | Xanthene derivatives |
| JPS54112874A (en) * | 1978-02-23 | 1979-09-04 | Yoshitomi Pharmaceut Ind Ltd | Thioxanthene derivative |
| JP3152941B2 (ja) | 1996-08-26 | 2001-04-03 | ファイザー インク． | スピロ環式ドーパミンレセプターサブタイプリガンド |
| US7014925B2 (en) * | 2003-04-29 | 2006-03-21 | Canon Kabushiki Kaisha | Heterogeneous spiro compounds in organic light emitting device elements |
| US20080207738A1 (en) * | 2007-02-28 | 2008-08-28 | Cancure Laboratories, Llc | Drug combinations to treat drug resistant tumors |
-
0
- BE BE758919D patent/BE758919A/xx unknown
-
1969
- 1969-11-15 DE DE19691957490 patent/DE1957490A1/de active Pending
-
1970
- 1970-10-08 GB GB1289209D patent/GB1289209A/en not_active Expired
- 1970-10-12 ZA ZA706933A patent/ZA706933B/xx unknown
- 1970-10-13 IL IL35443A patent/IL35443A/en unknown
- 1970-10-23 NL NL7015562A patent/NL7015562A/xx unknown
- 1970-10-23 DK DK539570AA patent/DK126044B/da unknown
- 1970-10-25 CS CS727334A patent/CS162733B2/cs unknown
- 1970-10-25 CS CS727336A patent/CS162735B2/cs unknown
- 1970-10-25 CS CS7199A patent/CS162732B2/cs unknown
- 1970-10-25 CS CS727337A patent/CS162736B2/cs unknown
- 1970-10-25 CS CS727335A patent/CS162734B2/cs unknown
- 1970-11-03 PL PL1970144225A patent/PL83016B1/pl unknown
- 1970-11-04 SE SE7014892A patent/SE370400B/xx unknown
- 1970-11-10 FR FR7040459A patent/FR2073359B1/fr not_active Expired
- 1970-11-12 CA CA097,969A patent/CA954133A/en not_active Expired
- 1970-11-13 AT AT530571A patent/AT300802B/de not_active IP Right Cessation
- 1970-11-13 AT AT530471A patent/AT300801B/de not_active IP Right Cessation
- 1970-11-13 CH CH469673A patent/CH565173A5/xx not_active IP Right Cessation
- 1970-11-13 CH CH1681770A patent/CH564008A5/xx not_active IP Right Cessation
- 1970-11-13 CH CH469573A patent/CH561199A5/xx not_active IP Right Cessation
- 1970-11-13 AT AT530671A patent/AT300803B/de not_active IP Right Cessation
- 1970-11-13 AT AT530371A patent/AT298488B/de active
- 1970-11-13 US US00089489A patent/US3721672A/en not_active Expired - Lifetime
- 1970-11-13 AT AT1025370A patent/AT300799B/de not_active IP Right Cessation
- 1970-11-13 ES ES385518A patent/ES385518A1/es not_active Expired
- 1970-11-13 CH CH469873A patent/CH561201A5/xx not_active IP Right Cessation
- 1970-11-13 CH CH469773A patent/CH561200A5/xx not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |